Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Physio-Pathological Role of Extracellular Vesicles
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:15 pm
"Extracellular Vesicles in Cancer Biology"
8:15 pm - 8:35 pm
Discussion
8:35 pm - 9:10 pm
"Tissue Injury and Repair"
9:10 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Biogenesis, Composition and Characterization of Extracellular Vesicles
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Triggers for the Release of Extracellular Vesicles from Dendritic Cells"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Monitoring and Facilitating Functional Delivery of Extracellular Vesicle Cargo"
10:20 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
"Emerging Themes in the Budding of Proteins, Exosomes and Viruses"
11:35 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Epstein-Barr Virus LMP1 Hijacks the Host ESCRT-Dependent Cellular Machineries for Exosomal Excretion"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Glycine tRNA Halves Are Intrinsically Stable Entities Which Can Be Secreted NON-Selectively in EVs and Incorporated in Recipient Cells in a Homotypic Human Cell Model"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Extracellular Vesicles as Delivery Vehicles
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Engineered Extracellular Vesicles in Biomedical Applications"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Extracllular Vesicle Mimetics"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Production and Storage Parameters for Therapeutic Extracellular Vesicles"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Activity-Composition Analysis of MiRNA-Enriched Exosomes"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Modulation of Inflammatory Response by Extracellular Vesicles
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"HLSC-Derived EV Modulation of Inflammation and Fibrosis"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Extracellular Vesicles and Transplantation"
10:20 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
"Secretion of Extracellular Vesicle Surface-Associated DNA"
11:35 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Clinical Scale Production of Extracellular Vesicles in a Hollow Fiber Bioreactor"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Development of EV-Based Drug Formulations for Treatment of Neurodegenerative Disorders"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Role of Extracellular Vesicles in Infectious Diseases
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"HIV-1 Nef Secretion and Extracellular Vesicles"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"The Multiple Faces of Naked Virus-Induced Extracellular Vesicles"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Extracellular Vesicles from Cell-Walled Microbes: Fungi and Gram Positive Bacteria"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Malaria Parasites Regulate Secretion of Exosomes Carrying Distinct Cargo"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
The Role of Extracellular Vesicles in Cancer Microenvironment and Metastasis
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Exploiting Exosomes for Treatment of Cancer"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Extracellular Vesicle MicroRNAs in the Tumor Microenvironment"
10:20 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
"Extracellular Vesicles and Cancer Stem Cells"
11:35 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Prostate Cancer Sheds avβ3 Integrin In Vivo Through Exosomes that Are Transferred to Other Cells in the Tumor Microenvironment"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Molecular Subtypes and Differentiation of Glioma Stem Cells as Determinanants of Extracellular Vesicle Profiles and Endothelial Cell Stimulating Activities"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Diagnostic and Therapeutic Applications of Extracellular Vesicles
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Dissection of the Heterogeneity of Extracellular Vesicles in Supernatants of Mesenchymal Stem/Stromal Cells"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Imaging and Quantification of Extracellular Vesicles"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Production of Functionally Bioactive Extracellular Vesicles from Immortalized Human Neural Stem Cells"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"A Highly Diverse and Scalable Progenitor Stem Cell Bank for Identifying and Producing Therapeutic Extracellular Vesicles"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
The Role of Extracellular Vesicles in Neurobiology
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Exosome Signaling in Brain Development"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"The Role of Extracellular Vesicles in Neurodegenerative Diseases"
10:20 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
"Defining Exosome Properties for Neuronal Trafficking"
11:35 am - 11:50 am
Discussion
11:50 am - 12:20 pm
"RNA Transfer Across Synaptic Boutons Using Extracellular Vesicles and a Viral-Like Mechanism"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
The Role of Extracellular Vesicles in Stem Cell Biology and Potential Clinical Applications
5:30 pm - 5:35 pm
Introduction by Discussion Leader
5:35 pm - 5:50 pm
"Extracellular Vesicles from Potent and Non-Potent Cardiosphere-Derived Cells and from Mesenchymal Stem Cells Elicit Different Immunomodulatory Properties"
5:50 pm - 5:55 pm
Discussion
5:55 pm - 6:10 pm
"Human Amnion Cell-Derived Extracellular Vesicles in the Treatment of Bronchopulmonary Dysplasia and Associated Pulmonary Hypertension"
6:10 pm - 6:15 pm
Discussion
6:15 pm - 6:45 pm
"Extracellular Vescicles and Acute Kidney Injury"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:15 pm
General Discussion
7:15 pm - 7:30 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure