Deciphering Extracellular Vesicles: Unlocking the Mysteries of EV Biogenesis, Cargo, and Therapeutic Potential with New Technologies

July 27 - 28, 2024

Chairs

and

Grand Summit Hotel at Sunday River

97 Summit Road

Newry, Maine, United States

Venue and Travel Information

Conference Description

The Extracellular Vesicles GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The Gordon Research Seminar on Extracellular Vesicles is a unique opportunity for graduate students, postdoctoral fellows, and other early-career scientists to present their ideas and techniques, share their exciting research findings, and build collaborative relationships with colleagues and peers in a supportive and non-intimidating environment. The seminar is structured to allow ample time for networking and interactions with fellow researchers to promote professional growth and success.

Related Meeting

This GRS will be held in conjunction with the "Extracellular Vesicles" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Elucidating Extracellular Vesicle Modulation of Disease and Clinical Potential Discussion Leader:
3:45 pm - 3:55 pm	"Delivery of Proteolysis Targeting Chimeras Through Extracellular Vesicles for Treating Triple Negative Breast Cancer"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 4:10 pm	"The Role of Keratinocyte-Derived Exosomes in Painful Diabetic Neuropathy"
4:10 pm - 4:15 pm	Discussion
4:15 pm - 4:25 pm	"Investigating the role of Non-Small Cell Lung Cancer Extracellular Vesicles in Altering Neutrophil Function and Metabolism"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Deciphering Extracellular Vesicle Biogenesis and Functionality Discussion Leader:
7:30 pm - 7:45 pm	"Plasma Extracellular Vesicles Dampen Neutrophil Inflammatory Responses and Allow Macrophage Imprinting with an Anti-Inflammatory Signature"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Morphine Limits Neural-Bone Crosstalk via Suppression of Extracellular Vesicles"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Identifying Molecular Drivers of Extracellular Vesicle-Mediated RNA Transfer"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Tailoring Extracellular Vesicles with Notch Ligands to Treat Vascular Injuries"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Exploring Extracellular Vesicles in Skeletal Muscle Under Varying Conditions for Therapeutic Nanomedicine in Space"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Rab GTPases Cooperate with the Exocyst Complex to Release Skeletal Muscle Extracellular Vesicles upon Ca2+ Flux"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Methods to Develop Extracellular Vesicle Rigor and Analysis Discussion Leader:
9:00 am - 9:35 am	"Enrichment of Extracellular Vesicles and Viral-Like Particles by Tetraspanin Engineering and Immuno-Capture to Improve Payload Delivery"
9:35 am - 9:45 am	Discussion
9:45 am - 9:55 am	"Cell Culture Mechanics are Important for EV Generation and Cargo Loading"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Pipeline for Novel Neuron Extracellular Vesicle Marker Discovery and Measurement of Internal Cargo Proteins"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	"Engineering MRI-Detectable EVs to Study Breast Cancer Metastasis Organotropism in vivo"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	"pH-Responsive Biomaterials for the Isolation of Extracellular Vesicles from Biofluids"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	"Isolation of EVs and Viruses Using Microfluidic TFF-Based Methods"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	The Impact of Extracellular Vesicles from Non-Model Systems Discussion Leader:
1:30 pm - 1:45 pm	"From Bacteria with Love: Extracellular Vesicles as Mediators of Bacterial and Immune System Communication"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:05 pm	"Characterizing Probiotic Yeast Extracellular Vesicles"
2:05 pm - 2:10 pm	Discussion
2:10 pm - 2:25 pm	"Follow the Fate of Tumor Derived EVs"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Conference Links

Conference History Extracellular Vesicles

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