Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Starting Early Embryogenesis
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:20 pm
"Developmentally Programmed Tankyrase Activity Licenses Progression of Embryonic Genome Activation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Imaging How Cells Choose Their Fate, Shape and Position in the Living Embryo"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Embryonic Origins of Pluripotency"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Stem Cell Maintenance, piRNAs and Monospermic Fertilization"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Gamete Fusion Mechanisms"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"The Molecular Underpinnings of the C. elegans Fertilization Synapse"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Species-Specificity of Fertilization"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"TMEM95 Is Required for Sperm-Egg Membrane Fusion"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Signaling During Gamete Maturation and Fertilization
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"CatSper Regulation by PKA and the Importance of Acrosomal pH for the Acrosome Reaction"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Dissecting Non-Genomic Progesterone-Dependent Signaling Pathways that Induce Frog Oocyte Maturation"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"The Plasma Membrane Compartmentalization of Na/K ATPase During Sperm Activation Modulates Sperm Migration and Fertility in the Nematode C. elegans "
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"A Chloride Channel Provides the First Defense Against Abnormal Fertilization in Xenopus laevis "
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Evolution of Reproductive Strategies and Sperm Competition
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"The Evolutionary Significance of Post-Testicular Sperm Maturation: Insights from Birds, Reptiles and Mammals"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"How Variations in X Chromosome Segregation Support Skewed Sex Ratios in the Nematode Auanema rhodensis "
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Ejaculate Composition: The Roles of Rivals and Ageing"
11:00 am - 11:10 am
Discussion
11:10 am - 11:30 am
"Egg Activation Mechanisms in Drosophila : Uncovering 'Deep Homology'"
11:30 am - 11:40 am
Discussion
11:40 am - 11:45 am
Introduction by Discussion Leader
11:45 am - 11:55 am
"Metalloproteinase Activity Is Required for Release of Oocyte-Zonapellucida Adhesion"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Insights into Reproductive and Intellectual Disorders in Quiescent Oocytes"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Imaging the Structural Organization of Mammalian Spermatozoa from the Cellular to the Supramolecular Level"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Role of the Reproductive Tract During Gametogenesis and Fertilization
7:30 pm - 7:50 pm
"Characterizing Chromatin and Transcriptional States of Germ Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Intrinsic and Extrinsic Forces Are Major Drivers of Wolffian Duct Morphogenesis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Extracellular Vesicles in the Female Tract: Interaction of Exosomes with Sperm"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"A Changing Matrix: Ovarian Hyaluronan, Inflammation and Reproductive Aging"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Meiosis During Sperm and Egg Development
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Crossover Control During Meiosis"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"How Meiosis Ensures Accurate Chromosome Segregation into Sperm"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Oocyte Meiotic Progression in the Jellyfish Model Clytia hemisphaerica "
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"PATL Is Required for Oocyte Meiosis/Maturation and Early Development"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Niche Cells Spatially Restrict Stem-Cell Self-Renewal Signalling via Receptor-Ligand Degradation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Sperm Motility and Finding the Egg
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
"Cryo-Electron Microscopy Studies Provide New Insights into the Structure and Motility of Sperm Flagella"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Sperm Ca2+ Signaling Nanodomains in Motility Regulation: CatSper Channels and Beyond"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"New Insights into Molecular Pathways Leading to Human Sperm Capacitation"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Selected Poster Presentations
Short talks selected from the posters.
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:20 am
"Characterization of Candidate Fusexin-Like Gamete Fusion Proteins on Mammalian Eggs"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Change in Energy Metabolism During Sperm Capacitation in Mouse Strains with Different Fecundity"
9:50 am - 9:55 am
Discussion
9:55 am - 10:05 am
"Novel SLO3 Inhibitors as Blockers of Human Sperm Capacitation"
10:05 am - 10:10 am
Discussion
10:10 am - 10:45 am
Coffee Break
10:45 am - 10:50 am
Introduction by Discussion Leader
10:50 am - 11:00 am
"Intercellular Communication Between the Luteinizing Hormone Receptor and the NPR2 Guanylyl Cyclase in Mouse Ovarian Follicles"
11:00 am - 11:05 am
Discussion
11:05 am - 11:15 am
"Egg Activation in Drosophila "
11:15 am - 11:20 am
Discussion
11:20 am - 11:30 am
"Indirect Sexual Selection Drives Rapid Evolution of an Intrinsically Disordered Sperm Protein"
11:30 am - 11:35 am
Discussion
11:35 am - 11:40 am
Introduction by Discussion Leader
11:40 am - 12:20 pm
"Historical Perspectives: Human Preimplantation Embryos, 1969-2019"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Assisted Reproductive Technologies: New Approaches and Ethical Concerns
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Bringing Andrology into the 21st Century: High Throughput Screening for Motile Human Sperm"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"ART in the Era of Single Cell Genomics"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"The Myth of the Designer Child: Parental Decision Making in an Era of Expanding Reproductive Options"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure