| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leader: Adan Guerrero (Instituto Gulbenkian de Ciência) |
| 3:45 pm - 4:15 pm | David Page (Whitehead Institute, MIT, HHMI)
"Mouse oogenesis: Genetically dissociating cell differentiation from meiosis" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Mediating Fertilization and Egg Activation |
| Discussion Leaders: Julia Floehr (University Hospital Aachen) and Mariana Wolfner (Cornell University) |
| 7:30 pm - 7:50 pm | Ingrid Carvacho (Boston Children's Hospital - Harvard Medical School)
"A TRP-channel mediates Ca2+ and Sr2+ influx in mouse eggs"
|
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Miranda Bernhardt (National Institutes of Environmental Health Sciences)
"Role of CACNA1H-mediated calcium influx in the mouse egg"
|
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Eileen Dietzel (University Hospital Aachen)
"Fetuin-B inhibits zona pellucida hardening"
|
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Matteo Avella (National Institutes of Health, NIDDK)
"ZP2 is the ligand for fertilization in mice and humans"
|
| 9:20 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Understanding Sperm Function |
| Discussion Leaders: Melissa Miller (University of California, Berkeley) and Takuya Nishigaki (Instituto de Biotecnologia-UNAM) |
| 9:00 am - 9:20 am | Veronica Aguirre (Pontificia Universidad Catolica de Chile)
"Role of Metalloproteases ADAM17 and ADAM10 and reactive oxygen species (ROS) in germ cell in diabetic rat testes: A possible explanation for infertility in diabetes"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Nadja Mannowetz (University of California, Berkeley)
"Characterization of the principal potassium channel of human spermatozoa"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Burak Ozkosem (McGill University)
"Absence of peroxiredoxin 6 impairs the fertilizing ability of DNA-damaged spermatozoa"
|
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Maria Gervasi (Center for Pharmacological and Botanical Studies)
"The endocannbinoid anandamide (AEA) regulates oviductal sperm selection in bovines by inducing sperm calcium release"
|
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Session |
| Discussion Leader: Matthew Marcello (Waksman Institute - Rutgers University) |
| Discussion with Former Fertilization and Activation of Development GRC Chairs |
| 1:30 pm - 2:30 pm |
Mentors:
- Janice Evans (Johns Hopkins Bloomberg School of Public Health)
- Alberto Darszon (Instituto de Biotecnologia-UNAM)
- George Gerton (University of Pennsylvania)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
