Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Cell-ECM Adhesion From Structure and Function
7:40 pm - 8:10 pm
"Global Responses to Extracellular Rigidity in Pancreatic Cancer"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Protein Organization in Adhesions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"β1 Integrin–FAK–Piezo1 Signaling Axis Drives In-Situ Stiffening Mediated ECM Remodeling and Invasion of 3D Breast Epithelium"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Study of Integrin Structure
9:00 am - 9:20 am
"In Vitro Structural Reconstitution of Focal Adhesion Complexes"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Mechanical Control of Enzymatic Processes via Talin"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Mechanosensitive Integrins: Structural Dynamics and Cellular Adaptation to External Stiffness"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:20 pm
General Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Mechanobiology: Molecules and Cells
6:00 pm - 6:20 pm
"LIM Domain Proteins Recognize Strained Actin in Adhesions"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"The Impact of ECM Viscoelasticity on Tissue Organization and Dynamics"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
ECM in Tissue Development in Fibrosis
9:00 am - 9:20 am
"Piezo-Dependent Surveillance of Matrix Stiffness Generates Transient Cells that Repair the Basement Membrane"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Dynamic Regulation of ECM Stability During Drosophila Development"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Collagen Binding Receptors Regulate Mitochondrial Function in Kidney Injury"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
General Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell-ECM Based Regulation of the Stem Cells and Tissue Homeostasis
6:00 pm - 6:20 pm
"Extracellular Matrix Regulates the Post-Injury Switch Between Fibrosis and Regeneration"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Epithelial Stem Cell-Matrix Interactions Confer Mechanical Resilience to the Peridermal Tissue"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Integrins, ECM and Cancer
9:00 am - 9:20 am
"Translation of Secretory mRNAs must Be Restrained During Early Oncogenesis to Enable α5β1-Integrin Mediated Generation of Fibronectin-Rich Tumour Initiation Niches"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Understanding 3D Cell Motility in Low-Viscosity Matrix"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"MET Endosomal Signalling and Cancer Cell Invasion"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:20 pm
General Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell-ECM Adhesion in the Immune System
6:00 pm - 6:20 pm
"Stromal/Immune Crosstalk Maintaining Lymph Node Structure and Function"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Adhesive Migration Strategies in the Immune Cell World"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Tension-Sensing Membrane Domains in Mechanoadaption and Mechanotransduction"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Imaging Cell-ECM Adhesion
9:00 am - 9:20 am
"On the Role of Talin as an Evolutionary Conserved Regulator of Cell Adhesion"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Unveiling the Dynamic Nanoscale Landscape of Integrins and Regulators"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
Short Talk Selected from Poster Abstracts
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
Short Talk Selected from Poster Abstracts
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
General Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
The Dynamic World of Cell-ECM Adhesion
6:00 pm - 6:20 pm
"Cross-Talk Between Cell Mechanics, Cell Shape and Cell Fate"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Morphogenetic Control of Mouse Germline Entry"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure