Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Cell-ECM Adhesion From Structure and Function
7:40 pm - 8:10 pm
"Global Responses to Extracellular Rigidity in Pancreatic Cancer"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Protein Organization in Adhesions"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"β1 Integrin–FAK–Piezo1 Signaling Axis Drives In-Situ Stiffening Mediated ECM Remodeling and Invasion of 3D Breast Epithelium"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Study of Integrin Structure
9:00 am - 9:20 am
"In Vitro Structural Reconstitution of Focal Adhesion Complexes"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Mechanical Control of Enzymatic Processes via Talin"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Mechanosensitive Integrins: Structural Dynamics and Cellular Adaptation to External Stiffness"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:20 pm
General Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Mechanobiology: Molecules and Cells
6:00 pm - 6:20 pm
"LIM Domain Proteins Recognize Strained Actin in Adhesions"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"The Impact of ECM Viscoelasticity on Tissue Organization and Dynamics"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
ECM in Tissue Development in Fibrosis
9:00 am - 9:20 am
"Piezo-Dependent Surveillance of Matrix Stiffness Generates Transient Cells that Repair the Basement Membrane"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Dynamic Regulation of ECM Stability During Drosophila Development"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Collagen Binding Receptors Regulate Mitochondrial Function in Kidney Injury"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
General Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell-ECM Based Regulation of the Stem Cells and Tissue Homeostasis
6:00 pm - 6:20 pm
"Extracellular Matrix Regulates the Post-Injury Switch Between Fibrosis and Regeneration"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Epithelial Stem Cell-Matrix Interactions Confer Mechanical Resilience to the Peridermal Tissue"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Integrins, ECM and Cancer
9:00 am - 9:20 am
"Translation of Secretory mRNAs must Be Restrained During Early Oncogenesis to Enable α5β1-Integrin Mediated Generation of Fibronectin-Rich Tumour Initiation Niches"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Understanding 3D Cell Motility in Low-Viscosity Matrix"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"MET Endosomal Signalling and Cancer Cell Invasion"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:20 pm
General Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell-ECM Adhesion in the Immune System
6:00 pm - 6:20 pm
"Stromal/Immune Crosstalk Maintaining Lymph Node Structure and Function"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Adhesive Migration Strategies in the Immune Cell World"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Tension-Sensing Membrane Domains in Mechanoadaption and Mechanotransduction"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Imaging Cell-ECM Adhesion
9:00 am - 9:20 am
"On the Role of Talin as an Evolutionary Conserved Regulator of Cell Adhesion"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
Short Talk Selected from Poster Abstracts
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Unveiling the Dynamic Nanoscale Landscape of Integrins and Regulators"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
Short Talk Selected from Poster Abstracts
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
Short Talk Selected from Poster Abstracts
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
General Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
The Dynamic World of Cell-ECM Adhesion
6:00 pm - 6:20 pm
"Cross-Talk Between Cell Mechanics, Cell Shape and Cell Fate"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
Short Talk Selected from Poster Abstracts
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Short Talk Selected from Poster Abstracts
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Morphogenetic Control of Mouse Germline Entry"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure