Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Global Impact of Food Allergy
7:40 pm - 7:55 pm
Opening Remarks
7:55 pm - 8:10 pm
Introduction by Discussion Leader
8:10 pm - 8:20 pm
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:35 pm
"NIAID's Strategic Approach to Food Allergy Research"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Alpha Gal in Rural African Subjects"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"The Five Ds of Food Allergy Prevention – Is There More to the Food Allergy Epidemic than Diet Alone"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Deciphering the Immunological, Molecular and Genetic Components of the Food Allergy Disorder Eosinophilic Esophagitis"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Food Allergy vs Tolerance: Understanding the Balance
9:00 am - 9:20 am
"Lessons We Have Learned from Early Childhood Exposure to Peanut"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Epidemiological Evidence for the Atopic March"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Optimizing Translation Research and Implementation of Best Practice of Care for Food Allergy"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Prevention of Symptoms with Oral Immunotherapy: What Is the Dose Threshold?"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"The Microbiome and Changing Patterns of Food Allergies in Asia"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"The Role of Staphylococcus aureus in Food Allergy"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Mitochondrial Control of Immune Tolerance to Allergens"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Food Surveillance by the Immune System"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Induction of Neonatal Tolerance Through Breast Milk"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Role of T Cells in Food Allergy
7:30 pm - 7:45 pm
"Pre-Immune Influence of Gamma Delta T Cells on B Lymphocytes and Antibodies"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Deconvoluting Heterogeneity in the CD4+ T Cell Responses to Food Allergen"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Mapping Epitope Targets of T Cells in Food Allergy"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Investigation of Peanut-Specific T Effector and T Regulatory Cells in Children Allergic and Tolerant to Peanut"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Regulatory T Cells in Food Allergy"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Immunological Mechanisms of Food Allergy: From Skin to Gut
9:00 am - 9:10 am
"In Pursuit of Immune Tolerance: Perspectives from the Immune Tolerance Network"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Practical Aspects of Early Peanut Introduction: Who Needs to Be Screened and How?"
9:25 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Immune Regulation at Barrier Surfaces"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Regulation of Type-2 Immunity and Inflammation"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Regulation of Allergic Responses to Food by Commensal Bacteria"
11:10 am - 11:20 am
Discussion
11:20 am - 11:30 am
"Innate Lymphoid Cell (ILC) Regulation of Host-Microbe Interactions"
11:30 am - 11:35 am
Discussion
11:35 am - 11:45 am
"Early Diet and Environment's Impact on Microbiome and the Development of Allergies"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Tissue Adaptation: Implications for Gut Immunity and Tolerance"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"The Interplay Between the Gut Microbiota and Food Allergy"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Protein and Peptide Chemistry Involved in Food Allergy
7:30 pm - 7:45 pm
Introduction by Discussion Leader: Probing the Immune Response in Food Allergy Using CyTOF
7:45 pm - 7:55 pm
"Mapping Epitope Targets of T Cells in Food Allergy"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Highly Multiplexed Analysis of Resident and Inflammatory Immune Cell Populations Using Multiplexed Ion Beam Imaging"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Early Life Innate Immune Signatures of Persistent Food Allergy"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Food Allergens: A Molecular Perspective"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Using Proteomics to Investigate Allergen Epithelial Transport and Subsequent Sensitization and Elicitation"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Mass Spectrometry to Complement Standardization of Complex Allergenic Extracts"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"The Role of 2S Albumins in Food Allergy"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Role of B Cells and Immunoglobulins in Food Allergy
9:00 am - 9:20 am
"Induction and Breaking of Allergen Tolerance, Role of T and B Regulatory Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Regulation of IgE B Cells"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Can Specific IgE and IgG4 Responses Help to Explain the Increases in Food Allergy?"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Analysis of B Cell Repertoires in Peanut Allergy"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Analysis of Antigen-Specific Repertoire in Relation to Peanut Allergy Phenotypes"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Inhibition of IgE: Receptor Interactions and Signaling"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"IgG1 Memory Cells Keep the Memory of IgE Responses"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"The Roles of IgE in Food Allergy"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Inhibitors of Histamine Releasing Factor Mitigate Anaphylactic Symptoms of Food Allergy in the Mouse Model"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
The Roles of Basophils, Eosinophils, and Mast Cells in Food Allergy
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 7:55 pm
"Deciphering the Roles of Mast Cells Versus Basophils in Food Allergy and Anaphylaxis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Terminating Mediator Release from Human Basophils and Mast Cells"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Novel Strategies to Prevent Mast Cell Activation in Anaphylaxis"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Two Doses of Ibrutinib Abrogates Skin Test Responses and Basophil Activation in Food Allergic Adults"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"IL-4 Signaling and IL-9-Producing Mucosal Mast Cells in Food Allergy"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Skin Mechanical Injury Promotes ILC2-Dependent Intestinal Mast Cell Expansion"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Role of the Epithelium in Allergic Disease
9:00 am - 9:20 am
"Role of Epithelial Barrier and Allergic Diseases"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Intestinal Epithelial Allergen Sampling and Food Allergy"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Crosstalk Between Intestinal Stem Cells and Immune Cells Modulate Epithelial Cell Fate"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Regulation of IL-33 by Dectin-1"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Mechanisms of Sensitization and Tolerance to Foods Through the Skin"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"What a Rare Immunodeficiency Can Teach Us About the Immunological Mechanisms of Food Allergy"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Immune Dysregulation in Humans and Mice"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"How to Avoid Allergens? Characterizing the Neuroimmune Mechanisms of Food Aversion"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Features of CC027/GeniUnc, an Orally Reacting Peanut Allergy Model"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Adjuvant-Free Intragastric Sensitization to Peanut in CC027/GeniUnc Mice"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Phenotypes and Endotypes in Food Allergy
7:30 pm - 8:00 pm
"IL-13/IL-4 in Allergic Inflammatory Diseases"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Food Allergies: Phenotypes: IgE or Not? Endotypes: Anaphylaxis or Not?"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Molecular Allergology in Diagnosis, Treatment and Prevention of Food Allergy"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Mechanistic Clues to What Makes Oral Immunotherapy Work"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Mucosal Immune Redirection in Food Allergy"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure