Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: The State of Food Allergy Research and Lessons from Other Immunology Research
To facilitate discussion about the current state of food allergy research and how we define the most pressing unmet needs we will juxtapose a talk on emerging therapies in food allergy and their mechanistic underpinnings with one focused on another clinical immunological disease.
7:40 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:40 pm
"Epithelial Barrier Hypothesis for the Development of Allergic and Other Inflammatory Diseases"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:25 pm
"Immune Modulation in IBD: A History of Basic Science Leading Clinical Transformations"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Innate and Adaptive Th2 Immunity in Neurodevelopment, Oncology and Autoimmunity
9:00 am - 9:20 am
"Role of TSLP in Oncology"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"IL-33 in Neurodevelopment"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"IL-4+ BATF+ T Follicular Helper Cells in IgG4-RD"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Peripheral and Follicular Helper T Cells"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Role of IgE in Tumor Immunology"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Galactose-a-1,3-Galactose Specific IgE Antibody"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lessons from Vaccinology for the Development of Rational Interventions in Food Allergy
7:30 pm - 7:40 pm
"Investigating Regulatory T Cell Control of Allergic Gut Inflammation"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:05 pm
8:05 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Transcriptomic Insights on Food Allergy"
8:40 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"B Cells Responses in Allergic Children During Oral Immunotherapy in Comparison to Natural Tolerance"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Eicosanoid Dysregulation and Pathogenic Th2 Immunity
9:00 am - 9:20 am
"Regulation of IL-9 Expression in T Helper Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"CRTh2 Regulation and Role in Th2 Cells and Type 2 Inflammatory Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"The Epithelial Unit in Eosinophilic Esophagitis and Food Allergy"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Eicosanoid Dysregulation in AERD"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"PGDM as a Specific Maker of Food Allergy"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"PPAR-Gamma+ CD4 Th2 Cells"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Neurosensory Pathways Relevant to Aversive Food Responses
7:30 pm - 7:40 pm
"Single-Cell RNA Sequencing Identifies Metabolic Characteristics of T Cells in Eosinophilic Esophagitis"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:05 pm
"Gut-Brain Axis and Potential Relevance to Food Allergy"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"IgE Dependent Taste Preference"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"House Dust Mites Activate Nociceptor-Mast Cell Clusters to Drive Type 2 Skin Inflammation"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Cutaneous Neuroimmune Interactions Control the Initiation of the Allergic Immune Response"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Regulation and Maintenance of Type 2 Immunity: Adaptive
9:00 am - 9:20 am
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"IL-4 Signaling and Allergen-Specific T Cells"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Allergen-Specific T Cell Phenotype Diversity"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"B Cell Regulation in Milk Allergy in Response to OIT"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Novel Approaches to Treating Allergic Disorders with Monoclonal Antibodies"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Risk Assessment Using Basophil Activation to Differentiate Reaction Severity and Threshold During Oral Peanut Challenges in the LEAP Studies"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Optimal TH2A Effector Function Requires Local Epithelial Cytokine Signaling"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation and Maintenance of Type 2 Immunity: Innate
7:30 pm - 7:50 pm
"Antigen-Specific Regulation of Mucosal Tolerance Versus Inflammation"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"IL-33 in Mucosal Immunity"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"iNKT Cells and Enteral Lipid Antigens"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Unknown Intestinal Epithelial Immunological Responses and Food Allergen Sampling"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Food Allergy Risk Determinants
9:00 am - 9:20 am
"Breast Milk as an Immune Modulator"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Food Allergy Risk Factors and Prevention"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"IgA, Microbiome and Food Allergy Risk"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"The IgEhi Endophenotype in Peanut Oral Immunotherapy"
11:10 am - 11:15 am
Discussion
11:15 am - 11:30 am
"The MALT1 Locus and Progression of Allergic Immunity"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Atopic Dermatitis Phenotypes in Childhood and the Development of Other Allergic Diseases"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"Baseline Characteristics of Peanut-Allergic Individuals During the Dupilumab as Adjunct to AR101 Clinical Trial"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Food Allergy Prevention: Clinical Science and Best Practice
7:30 pm - 7:40 pm
"Perinatal Factors and Food Allergy Development in Early Childhood"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:05 pm
"Oral Tolerance as Food Allergy Prevention"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Translating LEAP into Public Health"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Limitations of Oral Tolerance and Approaches Targeting the Skin"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure