Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Lessons Learned From Genetic Interventions Used in the Environment
7:40 pm - 8:00 pm
"Friendly™ Insects: Self-Limiting Male Deployments Delivering Targeted Biocontrol of Invasive Pests"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Use of the Boosted Sterile Insect Technique to Control Invasive Aedes Mosquitoes in Europe"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Debug at 9 Years: Successes, Failures and Lessons Learned From the Release of 100s of Millions of Mosquitoes"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Wolbachia for Reducing Aedes Aegypti Population and Dengue in Singapore"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Gene Drives, Genetics and Genetic Engineering
9:00 am - 9:15 am
"Ifegenia and pgSIT in Anopheles Gambiae: Novel Daughter-Killing, Genetic Sexing, and Male Sterilization Systems for Scalable, Non-Driving, Vector Control"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Mice Against Ticks: Engineering White-Footed Mice to Resist Lyme Disease Using Camera-Based Reproductive Monitoring"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Controlling Aedes Aegypti Population and How They Sense People"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Maleness-Associated Transgenes for the Control of Aedes Albopictus "
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Cleave and Rescue Gene Drive in Animals and Plants"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
"Recoded Mosquito Midgut Immunity and Gene Drive for Malaria Elimination in Africa"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Developing Safeguarding CRISPR-Cas9 Gene Drive in the Plant Pathogenic Fungus, Sphaerulina Musiva, to Mitigate Populus Diseases"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Expanding the Toolkit for Genetic Biocontrol of the Malaria Mosquito Anopheles Gambiae"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Design Features of the TP13 Gene-Drive System for Population Modification of Anopheles Malaria Vectors"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Manipulating Microbiomes to Affect Host Phenotypes and Control Populations
6:00 pm - 6:15 pm
"Manipulating the Human Skin Microbiome to Prevent Mosquito Bites and Pathogen Transmission"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:35 pm
"Novel Anti-Virals and Mosquitocidals From Mosquito-Associated Fungi"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 6:55 pm
"Modifying the Sperm Epigenome Aids A Maternally-Inherited Symbiont (Wolbachia )"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:15 pm
"Mitigating Candidatus Liberibacter Asiaticus Transmission Using Genetic Biocontrol"
7:15 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"Symbionts Technologies for Control of Mosquito-Borne Diseases"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"The Microbiome and Mosquito Vectorial Capacity: Rich Potential for Discovery and Translation"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:15 am
"Innovative Strategies for Sustainable Vector Control"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Progress Towards Germline Transformation of Ticks"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Engineering New CRISPR-Mediated Population Control Measures for Tephritid Pests"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Development and Testing of a Self-Limiting Gene Drive in Aedes Aegypti"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"pgSIT: An Improved Sterile Insect Technique for Insect Biocontrol"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
"Optimized Genetic Tools to Decode and Manipulate Mosquito Chemosensory Biology"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Leveraging DNA Repair for Scarless Transgene Removal"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Identifying Anopheles Genetic Target Candidates For Malaria Control Under Climate Change"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Social and Regulatory Science
6:00 pm - 6:15 pm
"Public Engagement for Gene Drive Technology"
6:15 pm - 6:25 pm
Discussion
6:25 pm - 6:40 pm
"International Governance of Gene Drive Research: Reconciling Divergent Priorities to Create an Enabling Environment for Innovation"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
"Stakeholder Engagement for Genetic Biocontrol"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
"Community Agreement for Gene Drive Research: Lessons Learned from a Phased Development Pathway in Preparations for a Gene Drive Field Trial"
7:30 pm - 7:40 pm
Discussion
7:40 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Manipulating Sex Determination
9:00 am - 9:15 am
"Engineering Repressible Female-Specific Lethality for Insect Population Biocontrol"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Insights From the Sex Determination Mechanism of the Model Parasitoid, Nasonia Vitripennis , and Their Application for Biocontrol"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Conditional Sex Transformation Systems in Lucilia Cuprina for Improved Screwworm Control"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"A Link to the Past: Using CRISPR/Cas9 Genome Editing Technology to Alter Sex Ratios Outside of the Sex Determination Pathway"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Making Males: From Medfly Biology to Medfly Control"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
"Developing a Novel Sex Ratio Distortion System in Anopheles Gambiae"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Generic Markers and Temperature-Sensitive Lethal Systems for Insect Pest Control"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Developing Gene Drives for Population Suppression of the Malaria Vector Anopheles Funestus "
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Sex Conversion and Selection Tools for Aedes Aegypti Population Control"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Mathematical Modeling to Predict Outcomes
6:00 pm - 6:15 pm
"Close-Kin Mark-Recapture Methods to Estimate Demographic Parameters of Mosquitoes and Implications for Control"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:35 pm
"Target Product Profiles for Replacement Drives and Biocontrol Using EMOD Malaria, an Agent-Based Mathematical Model of Malaria Transmission"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 6:55 pm
"Modeling Malaria Interventions to Inform Policy"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:15 pm
"Developing Strategies for Efficient Localisable Genetic Biocontrol"
7:15 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"Multistage Spatial Model for Informing Release of Wolbachia -Infected Mosquitoes as Disease Control"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"Investigating the Role of Different Ecological Density-Dependent Feedback on a 2-Locus Underdominance Gene Drive System"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Elucidating Vector-Pathogen Interactions with an Aim to Engineer Anti-Pathogen Effectors
9:00 am - 9:15 am
"Harnessing Gene Functions in Dengue Infection: Exploring Gene Drive as A Promising Genetic Control Strategy"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Curbing Vector-Borne Diseases: Versatile Combinations of Genetic Modifications for Pathogen Suppression in the Mosquitoes"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Making Mosquitoes Resistant to Virus Transmission"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Gut Binding Peptide-Mediated Identification of Insect and Pathogen Binding Domains"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Arthropod Salivary Proteins as Modulators of Vertebrate Vascular Biology and Pathogen Transmission"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
"Feeding Them Information: Regulation of Parasite Transmission by Host Genetics and Allergic Inflammation in Malaria"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"New Genetic Tools to Study Culex Mosquito-Virus Interactions"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Anopheles Melanization-Based Refractoriness to Plasmodium "
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Using CRISPR/Cas9 to Knock Out the Aedes aegypti SGS1 and Unveil their Interaction with Pathogens"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Population Genetics, Ecology, Field Work, and Monitoring
6:00 pm - 6:15 pm
"Patterns of Evolution in Invasive Arboviral Vectors: From Genomics to Physiology"
6:15 pm - 6:25 pm
Discussion
6:25 pm - 6:40 pm
"Island and Islet Specific Populations of Aedes Albopictus Across the Pacific"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
"Long Distance Transport Method of Sterile Male Mosquitoes"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
"Gene Drives Under Ecological Pressure"
7:30 pm - 7:40 pm
Discussion
7:40 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure