Sunday, Aug 5
7:30 p.m. | Opening Special Lecture: |
Roger Tsien, Professor and HHMI Investigator, Univ. of California at San Diego
Genetically encodable reporters of signal transduction and protein interactions
Monday, Aug 6
9:00 a.m. | Endocrine Regulation of Phosphorylation Cascades |
Session Chair - JoAnne Richards, Baylor College of Medicine
G. Stanley McKnight, Univ. of Wash
Protein Kinase A signaling
Natalie Ahn, Univ. of Colorado
Proteinomics and MAPK signal transduction
John Blenis, Harvard Medical School
Regulation of Cell Motility, Survival and Proliferation by MAP kinase and RSK
Morris White, Joslin Diabetes Ctr and HHMI Investigator
Insulin receptor signaling through IRS-1
Monday, Aug 6
7:30 pm | Mechanisms of Signal Transduction |
Session Chair - Thomas Gelehrter, University of Michigan Medical School
Kunxin Luo, Univ. California at Berkeley
TGF-beta regulation of Smad signaling and Ski/Sno interactions
Bernd Groner, Inst. Biomed. Research, Frankfurt Germany
STAT5 signaling pathways
Michel Sanders, University of Minnesota
"Estrogen opposes apoptosis through transcriptional and post-transcriptional mechanisms"
Cynthia Kenyon, UCSF
Endocrine regulation of Aging in C. elegans
Tuesday, Aug 7
9:00 a.m. | Hormone Signaling and Integration of Physiological Control |
Session Chair - Diane Robins, University of Michigan Medical School
JoAnne Richards, Baylor College of Medicine, Houston
New kinase signaling pathways in the ovary
Mona Nemer, Clinical Research Inst. Montreal
Nuclear signaling by G-protein coupled receptors during cardiac cell growth
Holly Ingraham, Univ. of California at San Francisco
Hormone signaling and neuroendocrine control
David Moore, Baylor College of Medicine
Natural products and nuclear receptors in cholesterol regulation
Tuesday, Aug 7
7:30 pm | Hormones and Development |
Session Chair - Holly Ingraham, University of California, San Francisco
Pamela Mellon, Univ. of California, San Diego
Homeodomain proteins controlling the gonadotropin-releasing hormone gene in hypothalamic neurons
Ming-Jer Tsai, Baylor College of Medicine
Neural Development and the Nuclear Orphan Receptor COUP-TF
Carl Thummel, Univ. of Utah and HHMI Investigator
Molecular mechanisms of steroid hormone action in Drosophila
Wednesday, Aug 8
9:00 a.m. | Endocrine Control of Cell Growth and Differentiation |
Session Chair - John Nilson, Case Western Reserve Univ. School of Medicine
Axel Thomson, MRC Human Reproductive Sciences Unit
Androgens and Regulation of Prostatic Organogenesis and Growth
Carol Lange, University of Minnesota Cancer Center
Regulation of Progesterone Receptor Stability and Transcriptional Activity in Breast Cancer
Aubrey Thompson, University of Texas Medical Brance
Regulation of intestinal epithelial cell proliferation: protein kinase C, TGF-betaRII, dietary lipids, and colon cancer
Jeff Rosen, Baylor College of Medicine
Mammary gland development and breast cancer: Insights from transgenic and knockout mouse models
Wednesday, Aug 8
7:30 pm | Transcription Complexes and Chromatin Structure |
Session Chair - Michel Sanders, University of Minnesota
Leonard P. Freedman, Memorial Sloan-Kettering Cancer Center
Mediating Transcriptional Activation by Nuclear Hormone Receptors
E. Brad Thompson, University of Texas Medical Branch
Role of AF-1 Transactivation Domain Folding and the Control of Glucocorticoid Receptor Transcriptional Activity
Shelley Berger, Wistar Institute
Chromatin Structure and histone phosphorylation
Gordon Hager, NIH
The dynamics of nuclear receptor interactions with genomic targets
Thursday, Aug 9
9:00 a.m. | Nuclear Receptors and Associated Factors |
Session Chair - Christopher Glass, University of California, San Diego
Ching-yi Chang (McDonnel laboratory), Duke University Medical Center
Targeting Receptor:Cofactor interactions for new Drug Discovery
Paolo Sassone-Corsi, University of Strasbourg
Coupling Signaling to Transcription: A Physiological Outlook
Jae Woon Lee, Chonnam National University, Korea
A Novel Transcription Coactivator ASC-2 and its Physiological Functions
Michael Rosenfeld, UCSD/HHMI, CA
Molecular and physiological functions of NcoR and SMRT
Thursday, Aug 9
7:30 pm | Special Symposium: Mechanisms of Hormone Networking |
Discussion leader: Gary Firestone, Conference Chair
Keith Yamamoto, UCSF, CA
Receptors as Components of Transcriptional Regulatory Complexes: Mechanisms, Composition, and Continuous Recycling
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