Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: The Hypothalamus From Individual Molecules to Sophisticated Behaviors
7:40 pm - 8:20 pm
"Building the Hypothalamus: From Form to Function"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Neuronal Regulation of Pre-Sleep Nesting Behavior"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"A Forebrain Neural Substrate for Behavioral Thermoregulation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"A Novel Neuroendocrine Mechanism Underlying Lactational Hyperprolactinemia and Hyperphagia"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Hypothalamus and Complex Social and Inter-Species Behavior
9:00 am - 9:20 am
"Mapping the Behavioral and Neural Dynamics of Social Dominance and Defeat"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Neural Circuit Mechanism of Prosocial Behavior"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Identification of a Hypothalamic Locus Gating Behavioral Sex-Specificity"
10:15 am - 10:20 am
Discussion
10:20 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Amylin-Calcitonin Receptor Signaling in the cMPOA as a Possible Crossroad of Parental Care, Sociality, and Homeostatic Control"
11:15 am - 11:25 am
Discussion
11:25 am - 11:40 am
"Prior Experience with Insects Reduces Visual Stimulus-Induced Avoidance and Arrest Behavior in Mice"
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Antagonistic Neural Circuits Drive Opposing Behaviors Towards the Young in Females"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"An Approximate Line Attractor in the Hypothalamus that Encodes an Aggressive Internal State"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Rhythms in the Hypothalamus
7:30 pm - 7:50 pm
"Cellular, Molecular, and Physiological Adaptations of Hibernation"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Periodic Neurotransmitter Remodeling in a Collateralized Brainstem Neuron Type Regulates Adaptation to Seasonal Photoperiods"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Hypothalamic Regulation of Zebrafish Sleep"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Hypothalamic Circuitry Underlying the Circadian Control of Sexual Behavior and Reproduction"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Identifying Central Mechanisms of Glucocorticoid Circadian Rhythm Dysfunction in Breast Cancer"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Hypothalamus and Ingestive Behavior
9:00 am - 9:20 am
"Gut-Brain Signaling and the Control of Feeding Behavior"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Gut-Brain Signaling for Fluid Homeostasis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Complementary Lateral Hypothalamic Populations Resist Hunger Pressure to Balance Nutritional and Social Needs"
10:15 am - 10:20 am
Discussion
10:20 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Immune System Modulation of Gut-Brain Dynamics"
11:15 am - 11:25 am
Discussion
11:25 am - 11:40 am
"Conflicting Hunger with Self-Preservation Behavior"
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"A Novel Head-Fixed Behavioral System Reveals Simultaneous Dynamics of Lateral Hypothalamus GABA and Glutamate Cells During Operant and Consummatory Behaviors."
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:10 pm
General Discussion
12:10 pm - 12:25 pm
"A Simple Circuit Regulating Feeding: Connecting Interoceptive Sensing to Motor Actions"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:45 pm
"Oxytocin Neurons Enable Social Transmission of Maternal Behavior"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:10 pm
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
"The Cognitive (Lateral) Hypothalamus"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
"Preoptic BRS3 Neurons Increase Body Temperature and Heart Rate via Multiple Pathways"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Hypothalamic Expression of Threat and Precaution"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Hypothalamic Development, Cell Type Taxonomy and Architecture
9:00 am - 9:20 am
"A Battle of the Sexes in Hypothalamic Development"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Functional Cellular Framework for Sexually Dimorphic Social Behaviors"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Dopaminergic Zona Incerta Cells Release GABA"
10:15 am - 10:20 am
Discussion
10:20 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"A Molecular and Functional Atlas of Paraventricular Hypothalamic Neurons"
11:15 am - 11:25 am
Discussion
11:25 am - 11:40 am
"Single Cell Analysis Reveals Sex-Specific and Cell Type-Specific Features of the Aging Hypothalamus"
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Next-Generation Atlas Mapping of Hypothalamic Cell Types and Chemoarchitecture for Gene-Directed Targeting"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"Neural Control of the Homeostatic Need for Social Interactions"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"The Hypothalamus and Obesity"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Stress Induces Calcium Activity in Oxytocin Neurons and Astrocytes in the Mouse PVN In Vivo"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
"Modulation of Mouse Paraventricular Nucleus of the Hypothalamus Corticotropin Releasing Hormone Neurons in Acute Withdrawal from Chronic Alcohol Consumption"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Control of Feeding by a Bottom-Up Brainstem-Subthalamic Pathway"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Altered Hedgehog Signaling in Adult Neurons Results in Obesity"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Neuroendocrine Hypothalamus
9:00 am - 9:20 am
"Estrogenic Modulation of Homeostatic Neural Circuits"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Plasticity and Dysfunction of Hypothalamic CRH-Expressing Neurons Induced by Early-Life Adversity: Role of Microglia and Single-Cell Transcriptomics"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"AgRP Neuron Epigenomes across Hunger States Reveal Novel Transcriptional Effectors of Leptin"
10:15 am - 10:20 am
Discussion
10:20 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Adaptation to Parenthood by Neuroendocrine Network Reorganization"
11:15 am - 11:25 am
Discussion
11:25 am - 11:40 am
"Microglia-Mediated Pruning of Astrocytes Increases Vasopressin Neuron Activity in High Salt Diet"
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Running on Estrogen: Hormone-Sensitive MC4R neurons in the Ventromedial Hypothalamic Nucleus Drive Sex Differences in Physical Activity"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"Early Adversity Promotes Binge-Like Eating Habits by Remodeling a Leptin-Responsive Circuit that Connects the Lateral Hypothalamus to the Brainstem"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Hypothalamus and the Brain-Body Interface
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
"Visualize Intact Mammalian Bodies to Map the Brain-Body Interface"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Neurovascular Control of Body Weight"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Hypothalamic Mechanisms of Blunted Glucocorticoid Circadian Rhythms in Breast Cancer"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"A Multidimensional Coding Architecture of the Vagal Interoceptive System"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure