Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Initiation and Modulation of the Immune Response
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:10 pm
"Immune System and Tissue Homeostasis"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Imaging the Immune System to Reveal Its Functional Organization and Principles of Operation"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Germinal Centers in Humoral Immunity"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Gene Programming of Immune Cells
9:00 am - 9:20 am
"The Power of ONE: Immunology in the Age of Single Cell Genomics"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Multiple Mechanisms of T Cell Preparedness for Rapid Activation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"xCT and Cystine Uptake Regulates Th17 and Treg Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Novel Insights into Regulatory T Cell Differentiation and Function"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Regulatory Networks in the Differentiation of Effector and Regulatory T Cells"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"IgA Plasma Cells Express Unique Transcriptional Programs in the Gut and Bone Marrow"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Macrophage Diversity and Function in Human Tissue Affected by Autoimmunity"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Development, Function and Regulation of Innate Lymphoid Cells
7:30 pm - 7:50 pm
"Innate Lymphoid Cells and the Second Brain"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"How the Innate Adapts: Generating Diverse Human Innate Lymphoid Cells 'On Demand'"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Development and Specificity of Homeostatic Intestinal IgA"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Towards the Human Co-Receptome: A Systematic Exploration of the Immunoglobulin Superfamily Interactome"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Heterogeneity in the Pre-Immune CD4+ T Cell Repertoire"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Tissue Determinants of T Cell Differentiation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Epigenetic Regulation of Self-Antigen Expression in the Thymus"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Chronic Inflammation Permanently Reshapes the Tissue-Resident γδ Compartment"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Tools for T Cells: Decoding the T Cell Response Repertoire in Cancer, Autoimmunity and Infectious Diseases"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Quantifiable Predictive Features of Epitope-Specific Repertoire: Understanding TCR Repertoire Structure, Specificity and Plasticity"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Clonal Analysis of Salmonella-Specific Effector T Cells Reveals Serovar Specific and Cross-Reactive T Cell Responses"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cell-Cell Communications in Immunity
7:30 pm - 7:50 pm
"Mechanical Control of Cytotoxic T Cell Function"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Understanding T:B Synapses in Human Germinal Centers"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Stromal Activation in Cancer Immunology and Immunotherapy"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Neutrophil Extracellular Traps in Immunity and Disease"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Immune Regulation and Inflammation
9:00 am - 9:20 am
"Immunogenomics One Cell at a Time"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Regulatory T Cell Choreography Directed by Endogenous Self-Ligands"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Intravital Imaging of NFAT Signaling Reveals that Short-Lived Activation of Tumor-Associated T Regulatory Cells Instructs Cancer Immune Escape"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Mitochondrial Biology in T Cells"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Using Machine Learning and Systems Immunology to Predict Immune Diseases"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Pathogenic Th2 (Tpath2) Cells in Airway Inflammation: Fibrosis Inducing Tpath2 Cells"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Applications of Immunoengineering in Tissue Engineering and Regenerative Medicine"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Microbial Interactions at Barrier Surfaces
7:30 pm - 7:50 pm
"Dendritic Cells in Immune Regulation and Inflammation"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Microbial Regulation of Innate Immunity at Mucosal and Systemic Sites"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Microbiota-Immune Cell Interplay in Local and Systemic Disease"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Heterogeneity of Tissue-Resident Memory T Cells"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Imaging T Cell Responses in the Liver"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"T Cell Immunity in Acute and Chronic Viral Infection"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"IL-4Ra Expressing B Cells Govern CXCL13 Production by Fibroblastic Reticular Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Lessons from the Analysis of the Immune Response to Plasmodium falciparum "
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Novel Inborn Errors of Immunity and Syndromic Chronic Mucocutaneous Candidiasis"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Highly Multiplexed Epitope Tetramer Screening and Deep Phenotyping of T Cells over the Course of Natural Dengue Infection Using Mass Cytometry"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"The C-Type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Antibodies, Vaccines and Immunotherapies
7:30 pm - 7:50 pm
"New Vaccine Strategies Using Cytomegalovirus"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"From Data to Understanding Through Systems Vaccinology"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Potency-Reduced IL15/IL15Ra Heterodimeric Fc-Fusions Display Enhanced In Vivo Activity Through Increased Exposure"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Chlamydia-Activated B Cells as Cancer Immunotherapy"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Decoding Immune Recognition"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure