Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Fundamental Discoveries in Fungal Systems
7:40 pm - 8:10 pm
"Exploiting Fungal Pathogenesis for the Developments of Immunotherapies"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:50 pm
"A Tale of Two Cytokines: How Type 17 Cytokines Coordinate Immunity to Candida Albicans "
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Cutaneous Innate Lymphoid Populations Drive IL-17A-Mediated Immunity in Nannizzia Gypsea Dermatophytosis"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Candida Albicans Induces Metabolic Reprogramming of Intestinal Epithelial Cells to Affect Innate-Like Lymphocytes"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Tackling and Treating New and Neglected Pandemics
9:00 am - 9:20 am
"Host-Pathogen Interactions and Immune Responses in the Emergomyces Africanus Mouse Model of Infection"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Macrophages Promote the Development of Coccidioides Spores into the Parasitic Morphology"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Identification of Coccidioidomycosis Immunoreactive Peptides that Recall T-Cell Responses Indicating Past Exposure"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 10:50 am
"Innovation in the Diagnosis and Treatment of the Southeast Asian Fungal Infection Talaromycosis"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Nutritional Composition of the Histoplasma-Containing Phagosome"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Mgl2+ cDC2 Mediated Anti-Fungal Allergic Inflammatory Responses are Highly Dependent on a Glycolytic Switch, Orchestrated by Spore Uptake and the Local Lung Nutrient Environment"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Protective Efficacy of Nucleic Acid Vaccines Against Coccidioidomycosis"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Characterizing the Role of Vaginal Antifungal Immunity in Health and Diabetes"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Novel Insight into the Host-Fungal Interface by Young Investigators in Fungal Immunology
7:30 pm - 7:40 pm
"Targeting the Troublemakers: IgA Regulation of Commensal Fungi in the Gut"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Towards Understanding of Cryptococcus Neoformans Cell Surface Immune Modulators that Influence Pathogenesis and Disease Outcome"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Interleukin 4-Induced Gene 1 Tryptophan Metabolism in Type 2 Immunity: Tissue Specificity Matters"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Barrier Tissue Immunity to Fungi"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Fungi Rising: From Microbiome Dysbiosis to Infections"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Nutritional Immunity in Post-Viral 2° Mold Infection"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Strain-Specific Fungal Factors in the Regulation of Intestinal Immunity"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Characterization of an Atypical Cryptococcal ABC Transporter that Modulates the Immune Response Towards Pulmonary Infection"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Endogenous Fungal Communities in Health and Disease
9:00 am - 9:20 am
"Cross-Kingdom Interaction: A Commensal Yeast Promotes Salmonella Virulence"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Candida Fitness in on Mucosal Surfaces: Intra-Species Competition is Niche-Dependent"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"How Fungal Symbionts Evolved to Thrive in the Gastrointestinal Tract: Implications for Immunity and Inflammation"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Phagocytosis, New Technologies, Receptors, and Surprises"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Gastrointestinal Colonization by Candida Albicans Modulates Host Defense in Sepsis"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Identifying Gut Microbiota and Microbiota-Derived Metabolites which Modulate Candida Gastrointestinal Colonization"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"A Tale of Two: An IL-17-DUOX2 Axis and Gastrointestinal Colonization by Candida Albicans "
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"The Intratumor Mycobiome Promotes Lung Cancer Progression via Myeloid-Derived Suppressor Cells"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Fungal Regulation of Immune Homeostasis and Disease
7:30 pm - 7:50 pm
"Dissecting Human Candida Albicans-Reactive Th17 Responses in Health and Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Early-Life Intestinal Fungi as Regulators of Metabolic Inflammation and Energy Metabolism"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The Gut Mycobiome as Therapeutic Target in Liver Diseases"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Fungal Microbiota Promotes Immune Activation via the Gut-Lung Axis"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Nod2 as a Key Regulator of Kidney Th17 Immunity to Candida Albicans "
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Fungi at the Crossroads of Neurology and Immunology
9:00 am - 9:20 am
"Shape-Shifting into the Brain: Cryptococcus Morphotypes and Their Role in Dissemination"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Host Neuroimmunological Responses Against Cryptococcus Infection"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Fungus-Associated Itch Mechanism in Atopic Dermatitis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Focusing on the Brain: CNS-Specific Host-Candida Albicans Interactions"
11:10 am - 11:15 am
Discussion
11:15 am - 11:45 am
"Immunology of Human HIV-Related Cryptococcal Meningitis"
11:45 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metabolism at the Host-Fungal Interface
7:30 pm - 7:50 pm
"Host Response and Pathogenesis of Diverse Aspergillus Fumigatus Biofilm Morphotypes"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Microbiota Inter-Species Metabolic Interactions Connect Indole Metabolism, Immunity, and Tissue Regeneration to the Severity of Oral Candidiasis in Cancer"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Albumin Orchestrates a Natural Host Defense Mechanism Against Mucormycosis"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Skin Commensal Malassezia Promote Skin Homeostasis via the Aryl Hydrocarbon Receptor"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"An Intercellular IFN-STAT1-Cybb Axis Defines Protective Plasmacytoid DC to Neutrophil Crosstalk During Respiratory Aspergillus Fumigatus Infection"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"The Role of Fungal Trehalose-6-PhosphateSynthase (tps1) in Cryptococcus Neoformans -Murine Immune Interactions"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Fungal-Host Communication and Crosstalk
9:00 am - 9:20 am
"Dectin-1 and its Role in Adaptive Immunity"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Candida Auris Induces IFNg to Colonize Mammalian Skin"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Single-Cell Analysis of Human Airway Epithelium Identifies Cell Type-Specific Responses to Aspergillus and Coccidioides "
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Manipulation of Host Phagocytosis by Aspergillus Fumigatus and Therapeutic Opportunities"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Complement C3 Promotes Sterilizing Pulmonary Antifungal Immunity"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Crossing Kingdoms: Deciphering Fusarium Oxysporum’s Adaptation to Mammalian Hosts and Its Immune Modulation Strategies"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
A Tight Grip: Fungal Adhesion and Implications for Pathogenesis
7:30 pm - 7:50 pm
"Solving a Sticky Problem: Genetic Approaches to Target the Emerging Pathogen Candida Auris "
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Tight Grip or Loose Hold? Investigating the Adhesion Properties of Candida Parapsilosis and Candida Auris "
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Single Cell Transcriptomics Unveils Cell Type-Specific Immune Responses to Candida Auris Skin Infection"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"GPI-Anchored Aspartyl Proteases Target the Host Actin Nucleator Complex Protein to Suppress Epithelial Innate Immunity"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Commensal Training Ground of Candida Albicans "
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure