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Immunology of Fungal Infections (GRS)

Gordon Research Seminar

Modeling Host-Fungal Interactions for Fundamental and Translational Discovery

January 18 - 19, 2025

Chairs

and

Ventura Beach Marriott

2055 Harbor Boulevard

Ventura, California, United States

Venue and Travel Information

Conference Description

The Immunology of Fungal Infections GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

Globally, fungi are responsible for over one billion infections each year, causing approximately 1.5 million deaths yearly. Despite their impact on human health and healthcare costs, fungi have been largely overlooked and understudied. The WHO has recently released a fungal priority pathogens list to aid in the identification of fungal threats, underscoring the local and global relevance of fungal pathogens. Understanding the immunological mechanisms behind fungal infections permits the development of novel therapeutics and treatment strategies that can alleviate loss of life and the healthcare burden.

The GRS has a dynamic and diverse panel of speakers, representing the depth and breadth of the field of fungal immunology. Additionally, time is allocated for a mentorship session for attendees to meet with established career scientists. The seminar spans two days, beginning midday January 18, 2025 and concluding January 19, 2025. This is a seminar that is attended in addition to the Immunology of Fungal Infections Gordon Research Conference (GRC).

Related Meeting

This GRS will be held in conjunction with the "Immunology of Fungal Infections" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Keynote Session: Uncovering Immunological Frontiers in Fungal Pathogenesis Discussion Leader:
3:45 pm - 4:15 pm	"Across the Sands of Time: The Immunology of Latent Cryptococcus Infections"
4:15 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Host Control of Fungal Pathogens Discussion Leader:
7:30 pm - 7:40 pm	"A Novel Pair of C-Type Lectin Receptors that Inversely Regulate Antifungal Immunity"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	"Understanding the Role of Alveolar Macrophage Peroxisomes in the Antifungal Response Against A. Fumigatus"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 8:10 pm	"A Novel Dual-Reporter Strain Reveals Host Metabolism as a Key Driver Facilitating Aspergillus Fumigatus and Airway Epithelial Cell Interactions"
8:10 pm - 8:15 pm	Discussion
8:15 pm - 8:25 pm	"GM-CSF Orchestrates Granulocyte and Monocyte Responses During Cryptococcus Gattii Infection"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:40 pm	"Non-Canonical Functions of Macrophage IRE1a Promote Fungicidal Activity"
8:40 pm - 8:45 pm	Discussion
8:45 pm - 8:55 pm	"Innate B Cells Promote Anti-Fungal Immunity in Aspergillus Pneumonia"
8:55 pm - 9:00 pm	Discussion
9:00 pm - 9:10 pm	"Lung Epithelium-Endothelium Dynamics Responsible for the Rapid Recruitment of Neutrophils Following Coccidioides Posadasii cts2/ard1/cts3 Infection"
9:10 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	"Epitranscriptomic Signaling in Mucosal Defenses Against Candida Albicans"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Fungal Avoidance and Defense from Immunological Control Discussion Leader:
9:00 am - 9:10 am	"Chronic Production of IL-23 Activates a Functional Heterogeneity of IL-17F-Producing Cells, Which Untangle the Immunological Signature in Young Adult Cystic Fibrosis Patients with Early ABPA Diagnosis"
9:10 am - 9:15 am	Discussion
9:15 am - 9:25 am	"Coordination of Type 2 Immunity by Oxysterols Promotes Persistent Infection in Fungal Granulomas"
9:25 am - 9:30 am	Discussion
9:30 am - 9:40 am	"Copper Driven Mutualism of Pathogenic Fungal: Bacterial Interactions"
9:40 am - 9:45 am	Discussion
9:45 am - 9:55 am	"Tumor Necrosis Factor-A Coordinates the Macrophage Innate Immune Response to Histoplasma Capsulatum"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Metabolic Imprinting Regulates Protective Epithelial Memory During Candida Albicans Infections"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	"Unveiling Immune Evasion: How HCMV and cmv-IL-10 impair Dendritic Cell Responses to Aspergillus Fumigatus Co-Infection"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	"Interkingdom Interactions with Candida Albicans Promote Group B Streptococcal Fitness"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	"The Gut-Lung Axis: Absence of a Gut Microbiome Significantly Affects Pulmonary Immune Responses to Aspergillus Fumigatus"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Advancing Careers in Fungal Immunology and Collaborative Science Discussion Leader:
1:30 pm - 2:30 pm	Panel Discussion Building Careers Through Mentorship
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Tulane School of Medicine CTRII

Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number 1R13AI188921-01. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Conference History Immunology of Fungal Infections

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