Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Metabolite Signaling in Macrophages
Discussion Leader: Denis Mogilenko (Vanderbilt University Medical Cente, United States)
3:45 pm - 4:20 pm
Evanna Mills (Dana-Farber Cancer Institute, Harvard Medical School, United States)
"Metabolite Signaling in Macrophages as a Regulator of Thermogenesis"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metabolic Regulation of Cellular Processes in Immunity
Discussion Leader: Evanna Mills (Dana-Farber Cancer Institute, Harvard Medical School, United States)
7:30 pm - 7:45 pm
Hayeon Chung (Seoul National University, South Korea)
"Cholesterol Metabolism in Dendric Cells Regulates Neutrophilic Asthma via Control of PPARy"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Kristine Bertheussen (Leiden University, The Netherlands)
"Studying Nutrient Uptake at the Single-Cell Level"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Krishna Chinta (University of Alabama at Birmingham, United States)
"Mycobacterium Tuberculosis Infection Elicits Glucose-Dependent Changes in Neutrophil Immunometabolism and Effector Functions"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Julia Drolet (SUNY Upstate Medical University, United States)
"Serine is a Facilitator of Macrophage Adaptation to Hypoxia that Promotes Lactate Accumulation and Efferocytosis"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
David Ngai (Columbia University Medical Center, United States)
"Efferocytosis-Induced Trans Inflammatory Signaling is Necessary for Inflammation Resolution and Tissue Repair"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Michael Dahabieh (Van Andel Institute, United States)
"The Prostacyclin Receptor is a NRF2-Regulated Immune Checkpoint in CD8 T Cells"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Immune-Metabolic Targeting in Disease
Discussion Leader: Will Bailis (Children's Hospital of Philadelphia, United States)
9:00 am - 9:15 am
Felix Nettersheim (La Jolla Institute for Immunology, United States)
"Diet-Related Glycolytic Reprogramming Induces the Formation of Pro-Atherogenic Autoreactive CD4+ T Cells"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Margaret Bohm (University of Tennessee Health Science Center, United States)
"Bariatric Surgery-Associated Modulation of the Gut Microbiome Improves Immunotherapy Efficacy in Breast Cancer through Microbially Derived Metabolites"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Marcos Munoz (University of Illinois at Chicago, United States)
"Fructo-Oligosaccharides Supplementation Prevents Western Diet-Induced Hypothalamic Inflammation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Julia Chini (University of Pennsylvania, United States)
"Liver-Derived CD9 Regulates Adipose Tissue Inflammation and Metabolic Dysfunction during Obesity"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Marah Runtsch (Medical University of Graz, Austria)
"Lung Tumor Neutrophils Undergo Heterogeneic Metabolic Reprogramming during NSCLC"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Abhirami Thumsi (case western reservre university, United States)
"Inverse-Vaccine for Rheumatoid Arthritis Re-Establish Metabolic and Immunological Homeostasis in Joint Tissue"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Entrepreneurship in Immunometabolism
Discussion Leader: Dequina Nicholas (University of California Irvine, United States)
1:30 pm - 2:15 pm
Vasanthi Viswanathan (Vasanthi Viswanathan, United States)
"Ferroptosis: Basic Science, Drug Discovery and Entrepreneurship"
2:15 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes