SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:40 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:40 pm - 4:30 pm | Intracellular roles of ion channels and transporters |
| Discussion Leader: Merritt Maduke (Stanford University School of Medicine) |
3:40 pm - 4:00 pm | Lilia Leisle (MDC/FMP Berlin)
"ClC-7 is a slowly voltage-gated 2Cl-/1H+-exchanger" |
4:00 pm - 4:05 pm | Discussion |
4:05 pm - 4:25 pm | Stefanie Weinert (MDC Berlin)
"Biological advantage of Cl- transport coupled to H+ gradient over a simple chloride channel for endosomal/lysosomal physiology" |
4:25 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Lipid modulation of ion channel function |
| Discussion Leader: Andrea Bruggemann (Nanion Technologies GMBH) |
7:30 pm - 7:50 pm | Shizhen Wang (Washington University School of Medicine)
"Inter-subunit interactions determine PIP2 sensitivity of KirBac1.1" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Mark Zaydman (Washington University School of Medicine)
"PIP2 potentiates voltage-dependent gating by coupling voltage-sensor activation and pore opening in Kv7.1" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Helgi Ingolfsson (University of Groningen)
"Changes in membrane protein function through drug/amphiphile effects on membrane properties" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Amy Eastwood (Stanford University)
"Models of Mechanotransduction Channel Activation" |
9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Ion channel regulatory proteins |
| Discussion Leader: Shai Silberberg (National Institute of Health - NINDS) |
9:00 am - 9:20 am | Ademuyiwa Aromolaran (Columbia University)
"Illuminating Trafficking of KCNQ1/KCNE1 Channels In Heart" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Elke Bocksteins (University of Antwerp)
"The silent K+ channel subunit Kv6.4 induces hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Jenny Li (University of British Columbia)
"Essential Aspartate Anchor for ATP-sensitive potassium channels Gating" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Amanda Lewis (Northwestern University)
"Interaction between fast inactivation, DIVS4 movement, and open-channel block in expressed sodium channels" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | High resolution approaches for ion channel structure |
| Discussion Leader: Lesley Anson (Nature Communications) |
1:30 pm - 1:50 pm | Qufei Li (University of Chicago)
"Structural Basis of Lipid-driven Conformational Transitions In The KvAP Voltage Sensing Domain" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Jun Liao (UT Southwestern Medical Center)
"Structural Insight into the Ion-Exchange Mechanism of the Sodium/Calcium Exchanger" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |