SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | New Techniques in the Study of Ion Channels |
| Discussion Leader: Andrea Bruggemann (Nanion Technologies) |
3:45 pm - 4:00 pm | Ivana Martinic (French National Center for Scientific Research)
"Optical Imaging of Potassium Channels by Near Infrared Lanthanide Nanoparticles" |
4:00 pm - 4:05 pm | Discussion |
4:05 pm - 4:20 pm | Hasti Amiri (Columbia University)
"Individual Single-Walled Carbon Nanotubes with Enhanced and Highly Selective Transport Properties Mimic Natural Protein Ion Channels" |
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Ion Channel Regulation and Signaling |
| Discussion Leader: Crina Nimigean (Weill Cornell Medical College) |
7:30 pm - 7:50 pm | Manu Ben Johny (Johns Hopkins University)
"Conservation of Calcium/Calmodulin Regulation Across Sodium and Calcium Channels" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Jens-Peter David (University of Copenhagan)
"N-Glycosylation of KCNE5 Is Crucial for Sorting of the Subunit in Polarized Cells" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Michael Yuchi (University of British Columbia)
"Structural Insight into the Disease Mutations in Ryanodine Receptors" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Xiaowei Hou (Memorial Sloan-Kettering Cancer Center)
"Functional Reconstitution and Structural Flexibility of Orai" |
9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Channel/Ligand Interactions |
| Discussion Leader: Stephen Long (Memorial Sloan-Kettering Cancer Center) |
9:00 am - 9:20 am | Hector Salazar (Leibniz-Institut fur Molekulare Pharmakologie)
"Activation of AMPA-Type Glutamate Receptor Tetramers" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Anke Bill (Novartis Institute for Biomedical Sciences)
"Small Molecule Facilitated Degradation of ANO1 - A New Targeting Approach for Anticancer Therapies" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Reesha Patel (Indiana University School of Medicine)
"Epilepsy-Associated Mutant Voltage-Gated Sodium Channels Alter Resurgent Current Generation that Could Be Preferentially Targeted with Cannabidiol" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Nina Yuan (University of Wisconsin-Milwaukee)
"Development of High-Throughput Assays to Identify New Alpha Subtype-Selective GABAa Receptor Modulators to Treat Anxiety and Depression Disorders" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:45 pm | Biophysics of Ion Channel Gating |
| Discussion Leader: Harley Kurata (University of British Columbia) |
1:30 pm - 1:45 pm | David Posson (Weill Cornell Medical College)
"Calcium-Dependent Gating in MthK K+ Channels Occurs at the Selectivity Filter" |
1:45 pm - 1:55 pm | Discussion |
1:55 pm - 2:10 pm | Robin Kim (University of British Columbia)
"Molecular Basis of Retigabine Actions on the Neuronal M-Current" |
2:10 pm - 2:20 pm | Discussion |
2:20 pm - 2:35 pm | Rene Barro-Soria (University of Miami)
"KCNE3 Shifts the Opening of KCNQ1 Channels by Acting on S4" |
2:35 pm - 2:45 pm | Discussion |
2:45 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |