Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Function of Lipid Species
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:25 pm
"Novel Dimensions Of Plasma Membrane Asymmetry: Phospholipid And Cholesterol Abundance Imbalances And Their Remarkable Consequences"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
"Discovery of Remodeling PLA2s Involved In The Lands' Cycle"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Disruptions in Sphingolipid Metabolism and Associated Motor Impairments in an iPLA2ß Knock-out Mouse Model of Neuroaxonal Dystrophy"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Lipidomics Technology and Harmonization
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Rapid Lipid Detection Using Direct Mass Spectrometry to Guide Diagnosis and Treatment Options for Patients"
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Illuminating The Dark Lipidome With Isomer-Resolved Mass Spectrometry"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:05 am
"Evaluation of Orbitrap and Astral Mass Analyzers for High-Throughput Untargeted Lipidomics"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
"Status and Perspectives of the Lipidomics Reporting Checklist"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Interlaboratory Trial on Human Plasma Lipidome: Concept and First Data"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Identifying and Addressing Technical Challenges in Alignment of Plasma Lipidomic Datasets Across Platforms and Clinical Studies"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Lipidomics Scoring System for Data Quality Assessment"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Single Cell Lipidomics and Emerging Techniques
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
"Visualizing Lipid Trafficking at Subcellular Resolution"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
"Deep Characterisation of the sn-Isomer Lipidome Using High-Throughput Data-Independent Acquisition and Ozone-Induced Dissociation"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"10-Second Classification of Lung Cancer Subtypes by Picosecond Infrared Laser Mass Spectrometry: Evaluation of Diagnostic Power Across Various Tissue Models"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Understanding the Consequences of Plasmalogen Deficiency at the Synapse"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:50 am
"The Dynamics Of Lipid Metabolism - Alkyne Lipids As Sensitive Tracers"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:00 am
"Betaine Lipid Transport: a New Method to Study Lipid Trafficking in Cells"
11:00 am - 11:10 am
Discussion
11:10 am - 11:25 am
"Comprehensive Isotope Tracing of Fatty Acids in vivo Reveals Differences Between Primary Tumors and Metastatic Sites"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Tracer-Based Lipidomics to Study De Novo Ether Lipid Synthesis in Peroxisomal Disorders"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Tracking Neutral Lipid Metabolism in Hepatocytes and Adipocytes"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Analysis and Quantitation of Metabolically Labeled Phospholipids for Live-Cell Imaging Applications"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Lipid Modification and Derivatives
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
"Lipid Modifications In Cell Life And Death"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
"Lipid Modification as a Fundamental Therapeutic Concept"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Oxidized Lipids Cause Ceramide Accumulation and Insulin Resistance in Skeletal Muscle"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Wide-Scope Targeted Analysis of Bioactive Lipids by LC/MS/MS"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Lipids in Health and Disease
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Application Of Clinical Lipidomics In Diabetes & Neurodegeneration"
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Disentangling Complex Brain Lipid Phenotypes In Parkinson’s Disease"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:25 am
"A3907, A Clinical Systemic Apical Sodium-Dependent Bile Acid Transporter Inhibitor, Reprograms Fatty Acid Utilization Towards Omega-6 Metabolism, Promoting Reduced Liver Inflammation, Fibrosis, and Steatosis"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
"1-Deoxy(DH)Ceramides With Very Long Chain Fatty Acyls (24:0/24:1) are Specific Mediators of Neurotoxicity"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Probabilistic Graphical Modeling Approaches Identify Disease-Specific Features Within Complex Lipidomic Data From Parkinson’s Disease Patient Specimens"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"The Senescence Associated Lipidome of Dermal Fibroblasts Reflects The Mechanistic Cause of Senescence"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
"Adipose-Derived EVs : Lipid Candidates Of Metabolic Dysfunctions Associated With Obesity"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
"Exploring The Regulation of Plasma Lipids in Metabolic Disease"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Direct Targeting of Protein-Lipid Interactions"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Development of An Acylceramide Nanostructured Delivery System To Rescue The Skin Barrier in Patients with Ichthyosis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
"Revisiting The Lipidome Of Escherichia Coli, The Friend And Foe In Human Health"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
"The Gut-Liver Connection: How The Gut Microbiota Regulates Host Lipid Metabolism"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
"Intracellular Warfare: Tracing Lipidome Changes During Infection"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Integrated Analysis of Whole Blood Oxylipin and Cytokine Responses After Bacterial, Viral, and T Cell Stimulation Reveals New Immune Networks"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Bile Acid Analysis in Feces, Evaluation of Normalization Approaches"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Empowering Veterinary Clinical Diagnosis in Industrial Poultry Production by Ambient Mass Spectrometry: Lipidomics of Broilers with Poor Intestinal Absorption Capabilities"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Bioinformatics Tools and Multiomics Data Integration
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
"Lipidomics Tools: From Lipid Identification to Large Scale Lipidome Comparisons"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
"FALCON Powers Insights Into Fundamental Cell Biological Mechanisms"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Integrative Insights into Lipidomics, Genetics, and Disease Progression: Revealing Complexities in Cardiometabolic Disease"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Zooming in: Single-Cell Lipidomics Unveiled with MS Imaging for Deeper Molecular Insights"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure