Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Function of Lipid Species
Discussion Leader: Jeffrey McDonald (UT Southwestern Medical Center, United States)
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:25 pm
Ilya Levental (University of Virginia, United States)
"Novel Dimensions Of Plasma Membrane Asymmetry: Phospholipid And Cholesterol Abundance Imbalances And Their Remarkable Consequences"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:05 pm
Junken Aoki (University of Tokyo, Japan)
"Discovery of Remodeling PLA2s Involved In The Lands' Cycle"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Irina Alecu (University of Ottawa, Canada)
"Disruptions in Sphingolipid Metabolism and Associated Motor Impairments in an iPLA2ß Knock-out Mouse Model of Neuroaxonal Dystrophy"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Lipidomics Technology and Harmonization
Discussion Leader: Federico Torta (National University of Singapore, Singapore)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
Livia Eberlin (Baylor College of Medicine, United States)
"Rapid Lipid Detection Using Direct Mass Spectrometry to Guide Diagnosis and Treatment Options for Patients"
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
Yu Xia (Tsinghua University, China)
"Illuminating The Dark Lipidome With Isomer-Resolved Mass Spectrometry"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:05 am
Alaa Othman (ETH Zurich /Univesity of Zurich, Switzerland)
"Evaluation of Orbitrap and Astral Mass Analyzers for High-Throughput Untargeted Lipidomics"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
Dominik Kopczynski (University of Vienna, Austria)
"Status and Perspectives of the Lipidomics Reporting Checklist"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
Michal Holcapek (University of Pardubice, Czech Republic)
"Interlaboratory Trial on Human Plasma Lipidome: Concept and First Data"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
Kevin Huynh (Baker Heart and Diabetes Institute, Australia)
"Identifying and Addressing Technical Challenges in Alignment of Plasma Lipidomic Datasets Across Platforms and Clinical Studies"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
Harald Koefeler (Medical University of Graz, Austria) and Nils Hoffmann (IBG-5, Research Center Juelich, Germany)
"Lipidomics Scoring System for Data Quality Assessment"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Erin Baker (University of North Carolina, United States) and Kim Ekroos (Lipidomics Consulting Ltd., Finland)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Single Cell Lipidomics and Emerging Techniques
Discussion Leader: Sarah Hancock (Victor Chang Cardiac Research Institute, Australia)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
Haibo Jiang (The University of Hong Kong, Hong Kong SAR China)
"Visualizing Lipid Trafficking at Subcellular Resolution"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
Christer Ejsing (University of Southern Denmark, Denmark)
"Deep Characterisation of the sn-Isomer Lipidome Using High-Throughput Data-Independent Acquisition and Ozone-Induced Dissociation"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Arash Zarrine-Afsar (University Health Network, Canada)
"10-Second Classification of Lung Cancer Subtypes by Picosecond Infrared Laser Mass Spectrometry: Evaluation of Diagnostic Power Across Various Tissue Models"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
ROBERTO ANGELINI (Swansea University, United Kingdom)
"Understanding the Consequences of Plasmalogen Deficiency at the Synapse"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Tracing Lipid Metabolism
Discussion Leader: Michael Kiebish (BPGbio, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:50 am
Christoph Thiele (University of Bonn, Germany)
"The Dynamics Of Lipid Metabolism - Alkyne Lipids As Sensitive Tracers"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:00 am
Ying-Chen Lin (University of Oxford, United Kingdom)
"Betaine Lipid Transport: a New Method to Study Lipid Trafficking in Cells"
11:00 am - 11:10 am
Discussion
11:10 am - 11:25 am
Thomas Mathews (University of Texas Southwestern Medical Center, United States)
"Comprehensive Isotope Tracing of Fatty Acids in vivo Reveals Differences Between Primary Tumors and Metastatic Sites"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Frederic Vaz (Amsterdam UMC, The Netherlands)
"Tracer-Based Lipidomics to Study De Novo Ether Lipid Synthesis in Peroxisomal Disorders"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Ondrej Kuda (Institute of Physiology, Czech Academy of Sciences, Czech Republic)
"Tracking Neutral Lipid Metabolism in Hepatocytes and Adipocytes"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Caroline Knittel (University of California San Diego, United States)
"Analysis and Quantitation of Metabolically Labeled Phospholipids for Live-Cell Imaging Applications"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Lipid Modification and Derivatives
Discussion Leaders: Jetty Chung-Yung Lee (The University of Hong Kong, Hong Kong SAR China) and Martin Giera (Leiden University Medical Center, The Netherlands)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
Maria Fedorova (Technical University Dresden, Germany)
"Lipid Modifications In Cell Life And Death"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
Martin Giera (Leiden University Medical Center, The Netherlands)
"Lipid Modification as a Fundamental Therapeutic Concept"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Karin Zemski Berry (CU Anschutz, United States)
"Oxidized Lipids Cause Ceramide Accumulation and Insulin Resistance in Skeletal Muscle"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Takeshi Bamba (Kyushu University, Japan)
"Wide-Scope Targeted Analysis of Bioactive Lipids by LC/MS/MS"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Lipids in Health and Disease
Discussion Leader: Peter Meikle (Baker Heart and Diabetes Institute, Australia)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
Cristina Legido-Quigley (King's College London, United Kingdom)
"Application Of Clinical Lipidomics In Diabetes & Neurodegeneration"
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
Kim Ekroos (Lipidomics Consulting Ltd., Finland)
"Disentangling Complex Brain Lipid Phenotypes In Parkinson’s Disease"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:25 am
Peter Åkerblad (Ipsen Pharma, Sweden)
"A3907, A Clinical Systemic Apical Sodium-Dependent Bile Acid Transporter Inhibitor, Reprograms Fatty Acid Utilization Towards Omega-6 Metabolism, Promoting Reduced Liver Inflammation, Fibrosis, and Steatosis"
11:25 am - 11:35 am
Discussion
11:35 am - 11:45 am
Thorsten Hornemann (University Hospital Zurich, Switzerland)
"1-Deoxy(DH)Ceramides With Very Long Chain Fatty Acyls (24:0/24:1) are Specific Mediators of Neurotoxicity"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
Nathan Hatcher (Merck & Co., Inc., United States)
"Probabilistic Graphical Modeling Approaches Identify Disease-Specific Features Within Complex Lipidomic Data From Parkinson’s Disease Patient Specimens"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
Michaela Schirato (Medical University of Vienna, Department of Dermatology, Austria)
"The Senescence Associated Lipidome of Dermal Fibroblasts Reflects The Mechanistic Cause of Senescence"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Functional Lipidomics
Discussion Leader: Edward Dennis (University of California, San Diego, United States)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
Soazig Le Lay (Inserm, France)
"Adipose-Derived EVs : Lipid Candidates Of Metabolic Dysfunctions Associated With Obesity"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
Judith Simcox (University of Wisconsin, Madison, United States)
"Exploring The Regulation of Plasma Lipids in Metabolic Disease"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Johannes Morstein (UCSF, United States)
"Direct Targeting of Protein-Lipid Interactions"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Lukas Opalka (Charles University, Faculty of Pharmacy in Hradec Kralove, Czech Republic)
"Development of An Acylceramide Nanostructured Delivery System To Rescue The Skin Barrier in Patients with Ichthyosis"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Lipids and Microbiota
Discussion Leader: Gwendolyn Barceló-Coblijn (Health Research Institute of the Balearic Islands, Spain)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
Xue Li Guan (Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore)
"Revisiting The Lipidome Of Escherichia Coli, The Friend And Foe In Human Health"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
Josef Ecker (University Hospital Regensburg, Germany)
"The Gut-Liver Connection: How The Gut Microbiota Regulates Host Lipid Metabolism"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:35 am
Fikadu Tafesse (Oregon Health & Science University, United States)
"Intracellular Warfare: Tracing Lipidome Changes During Infection"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
Cecile Gladine (INRAE, France)
"Integrated Analysis of Whole Blood Oxylipin and Cytokine Responses After Bacterial, Viral, and T Cell Stimulation Reveals New Immune Networks"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Hans-Frieder Schött (National University of Singapore (NUS), Germany)
"Bile Acid Analysis in Feces, Evaluation of Normalization Approaches"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Alessandra Tata (Istituto Zooprofilattico Sperimentale delle Venezie-PIVA00206200289, Italy)
"Empowering Veterinary Clinical Diagnosis in Industrial Poultry Production by Ambient Mass Spectrometry: Lipidomics of Broilers with Poor Intestinal Absorption Capabilities"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Bioinformatics Tools and Multiomics Data Integration
Discussion Leader: Thao Nguyen-Tran (University of Ottawa, Canada)
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:40 pm
Robert Ahrends (University of Vienna, Austria)
"Lipidomics Tools: From Lipid Identification to Large Scale Lipidome Comparisons"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:20 pm
Anna Greka (Harvard Medical School; Mass General Brigham; Broad Institute of MIT and Harvard, United States)
"FALCON Powers Insights Into Fundamental Cell Biological Mechanisms"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Christian Klose (Lipotype GmbH, Germany)
"Integrative Insights into Lipidomics, Genetics, and Disease Progression: Revealing Complexities in Cardiometabolic Disease"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Sara Tortorella (Mass Analytica SL, Italy)
"Zooming in: Single-Cell Lipidomics Unveiled with MS Imaging for Deeper Molecular Insights"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure
