Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Organization of Membranes and Proteins in Endocytosis
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:05 pm
"Intrinsic Disorder as an Organizing Principle for Membrane Traffic"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
"Dynamic Interplay Between Force and Membrane Geometry During Actin-Mediated Vesicle Formation"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Dynamic Remodeling of the Endolysosomal System
7:30 pm - 7:45 pm
"Multi-Functional ARF1 Compartments Mediate Secretory and Endocytic Trafficking by Maturing into Recycling Endosomes"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Mechanism and regulation of cargo entry into the Commander recycling pathway"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"EndoMAP, the Structural Proteome Landscape of the Endosomal System"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Visualization of how Cholesterol is Sequestered by Sphingomyelin in Membranes"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Spatial Organization of Adenylyl Cyclase and its Impact on Dopamine Signaling in Neurons"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"A Peroxisome-Derived Lipid and Its Regulation of Lysosomal Function"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Endosomes and Lysosomes in Human Physiology and Disease
9:00 am - 9:15 am
"From Recognition to Uptake: Unveiling a Key-Lock System that Drives the Capture of Biological Particles"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Characterizing the Signaling Pathways and Machinery that Regulate the Extracellular Digestion of Lipoprotein Aggregates by Macrophages"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Inside-Out Endosome Signaling: Proton Efflux via NHE6 Regulates the Rab7 GTPase-Activating Protein TBC1D5 Governing Endosome Maturation in Neurons"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"JIP4 Controls Cystinosin Stability at Lysosomes"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Subversion of Host Lysosomal Proteolysis by Coxiella Burnetii "
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"Dysfunctional Lysosomes in Batten Disease Impact the Lipid Composition of the Nuclear Envelope and Activate Apoptotic Signaling Pathways"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Endocytosis and Membrane Remodeling
1:30 pm - 1:45 pm
"BLTP2/KIAA0100, A Bridge-Like Lipid Transfer Protein, Functions at the Interface Between Endo- and Exocytosis"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
"DNA Nanotechnology for Spatiotemporal Omics of Endocytic Processes"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
"Deciphering the Intricate Hierarchy: Subtleties in Clathrin Heavy Chain Binding Boxes provide selectivity among Adaptor Proteins of Budding Yeast"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
