The Exploration and Expansion of Chemical Space in Natural Product Discovery

March 9 - 10, 2024

Chairs

and

Four Points Sheraton / Holiday Inn Express

1050 Schooner Drive

Ventura, California, United States

Venue and Travel Information

Conference Description

The Marine Natural Products GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

Related Meeting

This GRS will be held in conjunction with the "Marine Natural Products" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm	Keynote Session: Precision Molecule Editing and GenoChemetics to Accelerate Analogue Generation for Medicinally Relevant Natural Products Discussion Leader:
3:45 pm - 4:15 pm	"Precision Molecule Editing + GenoChemetics to Accelerate Analogue Generation for Medicinally Relevant Natural Products"
4:15 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Unveiling the Unique Role of Natural Products in Biological and Ecological Systems Discussion Leader:
7:30 pm - 7:45 pm	"Metabolomic Characterization of Membrane Vesicles and Their Roles in Mediating Microbial Competition"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Gram-Negative Bacteria-Specific Lipopeptide, Turnercyclamycin Involves Resistance Mechanisms Different to Colistin"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Biochemical Investigation of Piperazinone Biosynthesis in Micromonospora"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Heterologous Expression of Pseudovibriamides Isolated from the Marine Sponge-Associated Bacterium Pseudovibrio brasiliensis"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Characterizing the Mechanisms that Great Salt Lake Microorganisms Use to Adapt to Heavy Metal Concentrations"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Unlocking Animal Specialized Metabolite Biosynthesis: The Case of an Octocoral Briarane Diterpene Gene Cluster Family"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Novel Technologies for Natural Product Discovery Discussion Leader:
9:00 am - 9:15 am	"Machine Learning-Guided Discovery of Bioactive Natural Products"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Environmental Sampling and Affinity Selection Mass Spectrometry Screening of Estuarine Sediments for Natural Products Discovery"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Pseudopterosin Biosynthesis in Soft Corals: Solving a Decades Old Problem"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Discovery of Terpene Synthases in Brown Macroalgae"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Discovery of Pigments in a Deep-Sea Glass Sponge Possibly Made by a Symbiotic Bacterium"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"A Multi-Repository Scale Genomic and Chemical Search Engine to Enable the Discovery, Production, and Function of Natural Products"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Innovative Routes to Metabolite Diversification Discussion Leader:
1:30 pm - 1:45 pm	"New Depsipeptides from Marine Cyanobacteria and Molecular Targets"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:05 pm	"Are the Iron Uptake Mechanisms the Achilles Heel to Fight Against Pathogenic Bacteria?"
2:05 pm - 2:10 pm	Discussion
2:10 pm - 2:25 pm	"New Alkaloids from Millipedes with Ecological Impacts"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the National Center For Complementary & Integrative Health of the National Institutes of Health under Award Number R13AT012723. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health

Conference Links

Conference History Marine Natural Products

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