SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Matrix Metalloproteinases |
3:45 pm - 4:15 pm | Sharon Stack (University of Missouri) |
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Biochemistry and Biology of MMPs |
| Discussion Leader: Judith Bond (University of Pennsylvania) |
7:30 pm - 7:50 pm | Hsueh-Liang Fu (Wayne State University) "Regulation of Discoidin Domain Receptor-1 by Membrane-type 1 Matrix Metalloproteinase (MT1-MMP)" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Laurent Devel (CEA) "Exploiting The P2' Position Of Simple Pseudo-Dipeptides Leads To A Novel Family Of Potent Inhibitors Of MMPs And Other Metzincins" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Zhuoxin Yu (University of Medicine and Dentistry of New Jersey) "Matrix metalloproteinase (MMP) cleavage in a bacterial collagen system: Mechanism and Specificity" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Robichaud K Trista (University of Texas Health Science Center) "Exosite Interactions Determine Matrix Metalloproteinase Collagen Cleavage Specificities" |
9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | From Basic to Clinic I |
| Discussion Leader: Sean Gill (University of Washington) and Shuo Wei (University of Virginia) |
9:00 am - 9:20 am | Manisha Shah (St. Vincent's Institute of Medical Research) "An emerging role of MMP13 (Collagenase-3) in breast cancer angiogenesis" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Alisha Mendonsa (Vanderbilt University) "The role of MMP13 in the Steatotic Liver Microenvironment" |
9:50 am - 10:00 am | Discussion |
10:00 am - 11:00 am | Panel session: Jonathan Larkin (GlaxoSmithKline), Ariadne Letra (University of Pittsburgh School Dental Medicine), and Judith Bond (University of Pennsylvania) "I have my Ph.D...now what?" |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | From Basic to Clinic II |
| Discussion Leader: Major Gooyit (University of Notre Dame) |
1:30 pm - 1:50 pm | Sean Gill (University of Washington) "Tissue inhibitor of metalloproteinases 3 moderates the pro-inflammatory status of macrophages" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Jeffrey Lakritz (Ohio State University) "Novel Hp-MMP 9 Protein Complexes In Cattle-A Marker Of Systemic Neutrophil Activation" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |