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Matrix Metalloproteinases (GRS)

Gordon-Kenan Research Seminar

Everything You Wanted to Know about MMPs and You Were Afraid to Ask

August 6 - 7, 2011
Chairs and
Bryant University
1150 Douglas Pike
Smithfield, Rhode Island, United States
 Venue and Travel Information

Conference Description

The Gordon-Kenan Research Seminar on Matrix Metalloproteinases is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The first MMP GRS will focus on the basic and clinical research of Matrix Metalloproteinases, including their structure, functions in physiological and pathological processes and the research of novel MMP-based therapies. The GRS meeting seeks to attract graduate students and post-doctoral fellows, working in the MMP arena, to present and discuss their research projects with other young scientists and learn about the new advances in the field through a comfortable setting of their peers.

Related Meeting

This GRS will be held in conjunction with the "Matrix Metalloproteinases" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

SATURDAY
1:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmMatrix Metalloproteinases
3:45 pm - 4:15 pmSharon Stack (University of Missouri)
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmBiochemistry and Biology of MMPs
Discussion Leader: Judith Bond (University of Pennsylvania)
7:30 pm - 7:50 pmHsueh-Liang Fu (Wayne State University)
"Regulation of Discoidin Domain Receptor-1 by Membrane-type 1 Matrix Metalloproteinase (MT1-MMP)"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmLaurent Devel (CEA)
"Exploiting The P2' Position Of Simple Pseudo-Dipeptides Leads To A Novel Family Of Potent Inhibitors Of MMPs And Other Metzincins"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmZhuoxin Yu (University of Medicine and Dentistry of New Jersey)
"Matrix metalloproteinase (MMP) cleavage in a bacterial collagen system: Mechanism and Specificity"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmRobichaud K Trista (University of Texas Health Science Center)
"Exosite Interactions Determine Matrix Metalloproteinase Collagen Cleavage Specificities"
9:20 pm - 9:30 pmDiscussion
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amFrom Basic to Clinic I
Discussion Leader: Sean Gill (University of Washington) and Shuo Wei (University of Virginia)
9:00 am - 9:20 amManisha Shah (St. Vincent's Institute of Medical Research)
"An emerging role of MMP13 (Collagenase-3) in breast cancer angiogenesis"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amAlisha Mendonsa (Vanderbilt University)
"The role of MMP13 in the Steatotic Liver Microenvironment"
9:50 am - 10:00 amDiscussion
10:00 am - 11:00 amPanel session: Jonathan Larkin (GlaxoSmithKline), Ariadne Letra (University of Pittsburgh School Dental Medicine), and Judith Bond (University of Pennsylvania)
"I have my Ph.D...now what?"
11:00 am - 12:30 pmPoster Session II
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmFrom Basic to Clinic II
Discussion Leader: Major Gooyit (University of Notre Dame)
1:30 pm - 1:50 pmSean Gill (University of Washington)
"Tissue inhibitor of metalloproteinases 3 moderates the pro-inflammatory status of macrophages"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmJeffrey Lakritz (Ohio State University)
"Novel Hp-MMP 9 Protein Complexes In Cattle-A Marker Of Systemic Neutrophil Activation"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill out GRS Evaluation Forms
3:00 pmGordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm.

Contributors

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Conference History Matrix Metalloproteinases
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