| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Keynote Lecture |
| Stanley Korsmeyer, Harvard University
"Mitochondrial Gateway to Apoptosis" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Photo |
| 9:00 am - 12:30 pm | Signal Transduction I: Kinase Cascades |
| Discussion Leader: Jacques Drouin, University of Montreal |
| Marc Montminy, Salk Institute
"Transcriptional activation via PKA" |
| Melanie Cobb, University of Texas, Southwestern
"Map kinase cascades" |
| Coffee Break |
| Bing Ren, University of California, San Diego
"Dissecting gene regulatory networks using promoter microarrays" |
| Inez Rogatsky, University of California, San Francisco
"Role of GRIP1/TIF2 in glucocorticoid-mediated transrepression: |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Signal Transduction II: Signal-dependent transcription factors |
| Discussion Leader: Reed Graves, University of Chicago |
| Bruce Spiegelman, Dana Farber Cancer Institute
"Regulation of Glucose and Oxidative Metabolism through the Coactivator PGC-1" |
| Viroj Boonyaratanakornkit (Dean Edwards laboratory), University of Colorado Health Sciences Center
"Human Progesterone Receptor Activation of Cytoplasmic Signaling Pathways Through Direct SH3 Domain Interaction" |
| Paul Brindle, St Jude Hospital
"Functional analysis of CBP-dependent gene expression in vivo"
Sung-Hee Baek (Rosenfeld laboratory) University of California San Diego
"Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF- B and beta-Amyloid Precursor Protein" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Transcriptional Mechanisms I |
| Discussion Leader - Myles Brown, Dana Farber Cancer Institute |
| Bob Roeder, Rockefeller University
"The TRAP/mediator complex" |
| Tony Kozarides, Wellcome/CRC Institute
"Histone Modifications" |
| Coffee Break |
| Dino Moras, Laboratoire de Biologie et Genomic Structuales ICBMC
"Ligand binding in RORs and ERRs" |
| Eric Xu, Van Andel Research Institute
"Nuclear receptor: corepressor complexes" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Transcriptional Mechanisms II |
| Discussion Leader: Sophia Tsai, Baylor College of Medicine |
| Myles Brown, Dana Farber Cancer Institute
"Mechanisms of Estrogen receptor action" |
| Mitch Lazar, University of Pennsylvania
"Nuclear receptor corepressors" |
| Anastasia Kralli, University of Basel
"PGC-1 as a regulator of the orphan nuclear receptor ERRa" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Development I |
| Discussion Leader: Mona Nemer, Univeristy of Montreal |
| Jacques Drouin, University of Montreal
"Roles of t-Pit and Pitx factors in pituitary development" |
| Philip Lowry, University of Reading
"Proteases in the regulation of adrenal growth and development" |
| Coffee Break |
| Napoleone Ferrara, Genentech, Inc.
"Regulation of endocrine gland angio genesis by EG-VEGF" |
| Francis Sladek, University of California, Riverside
"How to repress a constitutively active nuclear receptor" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Development II |
| Discussion Leader: Ming-Jer Tsai, Baylor College of Medicine |
| Thomas Perlman, Ludwig Institute
"Orphan receptors in CNS development" |
| Orla Conneely, Baylor College of Medicine
"New Roles for Nurrs in development and homeostasis" |
| Catherine Thompson, Johns Hopkins Univeristy School of Medicine
"The mammalian hairless gene encodes a novel nuclear receptor corepressor" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Metabolic control I |
| Discussion Leader: Mitch Lazar |
| Chih-Hao Lee (Ron Evans laboratory), Salk Institute
"PPARs as integrators of lipid homeostasis" |
| Peter Tontonoz, UC Los Angeles
"Role of LXRs in macrophage gene expression and atherosclerosis" |
| Coffee Break |
| Richard Heyman, X-Ceptor Therapeutics
"Exploring the roles of LXRs and FXRs with synthesis ligands" |
| Yoonkwang Lee, Baylor College of Medicine
"Role of SHP in bile acid metabolism" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Metabolic control II |
| Discussion Leader: Chris Glass (University of California, San Diego) |
| Eleftheria Maratos-Flier, Research Division of the Joslin Diabetes Center
"Signaling by melanin concentrating hormone in the CNS and the periphery" |
| Michael Karin, University of California, San Diego
"Ikappa B kinase signaling: |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
