Molecular Mechanisms and Regulation of Sexual Reproduction

June 4 - 5, 2022

Chairs

and

Colby-Sawyer College

541 Main Street

New London, New Hampshire, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Meiosis is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The primary focus of this meeting is to explore the molecular mechanisms by which diploid progenitor cells give rise to haploid gametes (like sperm or egg) during the specialized cellular division called meiosis. The research presented throughout this seminar will encompass multiple aspects of meiosis through the use of various model organisms and novel experimental techniques, with special emphasis on mechanisms and control of meiotic regulation, mechanisms of chromosome segregation, meiotic DNA repair through homologous recombination, and quality control during gametogenesis.

Related Meeting

This GRS will be held in conjunction with the "Meiosis" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Molecular Mechanisms and Regulation of Sexual Reproduction Discussion Leader:
3:45 pm - 4:20 pm	"PCH-2 Both Promotes and Limits Crossover Recombination to Execute Crossover Control"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Mechanisms and Control of Meiotic Recombination Discussion Leader:
7:30 pm - 7:45 pm	"Investigating Age-Dependent Regulation of Recombination in Mammalian Spermatocytes"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Identification of Meiotic Recombination Nodule Proteins Utilizing Proximity Labeling"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"R-Loop-Induced Irreparable DNA Damage in C. elegans Meiosis"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"MLH1-Independent Roles of FANCJ in Mammalian Meiosis"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Meiotic Crossover Patterning: The Centromere Effect in Drosophila melanogaster"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Two Ways by Which C. elegans Male Parents With Crossover Failure Produce More Viable Progeny"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Mechanisms of Chromosome Segregation Discussion Leader:
9:00 am - 9:15 am	"SYPrisingly Separable Functions of the C. elegans Synaptonemal Complex"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Oligopaint DNA FISH Reveals Telomere-Based Meiotic Pairing Dynamics in the Silkworm, Bombyx mori"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Mammalian Spermatocytes Have the Capacity to Segregate Chromosomes Without Centriole Duplication and Centrosome Separation"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"The Spindle Checkpoint is Silenced in Budding Yeast Meiosis"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"The Role of Clb4 in S. cerevisiae Meiosis"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"Protein Diffusion Within the Synaptonemal Complex Spatially Coordinates Crossover Signals"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Quality Control During Gametogenesis Discussion Leader:
1:30 pm - 1:45 pm	"Interrogating Meiotic Quality Control Mechanisms Using Chemically-Induced Proximity"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:05 pm	"Investigating the Relationship Between Ime1 and Ume6 to Understand Early Meiotic Gene Regulation"
2:05 pm - 2:10 pm	Discussion
2:10 pm - 2:25 pm	"The DNA Damage Checkpoint Blocks Meiotic Progression Under Heat Stress Conditions"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health under Award Number R13HD102047. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Meiosis

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