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Metals in Biology

Gordon Research Conference

Chemical, Energetic and Metabolic Transformations

January 19 - 24, 2025

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chair

Vice Chair

Four Points Sheraton / Holiday Inn Express

1050 Schooner Drive

Ventura, California, United States

Venue and Travel Information

Application Information

The application deadline for this meeting was December 22, 2024. You may still submit an application, which may be considered by the conference chair if there is still room available.

Conference Description

The Metals in Biology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Bioinorganic Chemistry" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Non-Heme Iron Transformations Discussion Leader:
7:40 pm - 7:45 pm	Introduction by Discussion Leader
7:45 pm - 8:10 pm	"Advanced Spectroscopic Studies of Homogeneous and Enzymatic Catalysts"
8:10 pm - 8:20 pm	Discussion
8:20 pm - 8:45 pm	"Expanding the Reaction Space of Nonheme Enzymes"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	"Control of Reaction Outcome in C–H Activation by Iron Enzymes"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Metals and H₂S Signaling Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:30 am	"Signaling through Sulfide"
9:30 am - 9:40 am	Discussion
9:40 am - 10:05 am	"Model Systems for Investigating Sulfur and Selenium Bioinorganic Chemistry"
10:05 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:10 am	"Metal Thiolate Interactions and Divergent Sulfur Speciation"
11:10 am - 11:20 am	Discussion
11:20 am - 11:45 am	"The Role of Metal Centers in Protein Persulfidation"
11:45 am - 12:00 pm	Discussion
12:00 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. Organizers: and
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	COx and NOx Signaling and Poisoning Discussion Leader:
7:30 pm - 7:35 pm	Introduction by Discussion Leader
7:35 pm - 8:00 pm	"Polysaccharide Monooxygenases: Mechanism and Function"
8:00 pm - 8:15 pm	Discussion
8:15 pm - 8:40 pm	"CO Sensing Transcription Factors"
8:40 pm - 8:50 pm	Discussion
8:50 pm - 9:15 pm	"Progress in the Development of a Small-Molecule Antidote for Carbon Monoxide Poisoning"
9:15 pm - 9:30 pm	Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Metals in Signaling, Regulation and Storage Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:30 am	"Copper in Cell Signaling"
9:30 am - 9:40 am	Discussion
9:40 am - 10:05 am	"National Science Foundation Inorganic Phenotypes via Quantitative Element Mapping: Case Studies in Immunology, Reproduction and Cancer"
10:05 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:10 am	"The Amazing Facets of the Regulators of Metal Homeostasis of the FUR Family"
11:10 am - 11:20 am	Discussion
11:20 am - 11:45 am	"Multifunctional Zn Metallochaperones for Reactivation of Mutant p53"
11:45 am - 11:55 am	Discussion
11:55 am - 12:20 pm	"How Iron Enzymes Trigger Redox Sensing and Signaling"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Harnessing Bioinorganic Chemistry for Energy Storage and Transduction Discussion Leader:
7:30 pm - 7:55 pm	"Bacterial Redox Circuits Mediated by Cytochromes"
7:55 pm - 8:05 pm	Discussion
8:05 pm - 8:30 pm	"Multiheme Cytochromes c Enable Photocatalytic Hydrogen Production in a Nano-Bio System"
8:30 pm - 8:40 pm	Discussion
8:40 pm - 9:05 pm	"Magnetic Resonance Studies of Metalloenzymes"
9:05 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	"How Bacteria Manage the 2-Electron Oxidation of Mn(II) to MnO2 Bio-Mineral, Using a 1-Electron Multi-Copper Oxidase"
9:25 pm - 9:30 pm	Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Using Metal Coordination Chemistry to Target and Understand Disease Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:30 am	"Metal Compounds that Disrupt the Nucleolus"
9:30 am - 9:40 am	Discussion
9:40 am - 10:05 am	"Engineering Intracellular Iron Sequestration to Inhibit Cancer Growth"
10:05 am - 10:15 am	Discussion
10:15 am - 10:40 am	Coffee Break
10:40 am - 11:00 am	"Metallomics for Human Health: Uncovering the Biological Roles of Biometals and Discovery of Drug Candidates"
11:00 am - 11:10 am	Discussion
11:10 am - 11:30 am	"Tools for Photocontrol Over Endogenous Metals"
11:30 am - 11:40 am	Discussion
11:40 am - 12:00 pm	"Multifaced Organogold Chemistry for Therapy and Imaging"
12:00 pm - 12:10 pm	Discussion
12:10 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Proton Coupled Electron Transfer in Metalloproteins Discussion Leader:
7:30 pm - 7:35 pm	Introduction by Discussion Leader
7:35 pm - 8:00 pm	"PCET is the Engine of Radical Enzymology: The RNR Paradigm"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:35 pm	"Proton-Coupled Electron Transfer: Fair, but Maybe Not Square"
8:35 pm - 8:50 pm	Discussion
8:50 pm - 9:15 pm	"O₂ Binding, Activation and Cleavage within Single Crystals"
9:15 pm - 9:30 pm	Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Metallomics, Proteomics and Genomics Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:30 am	"Chirality in Siderophores: Genomic Origins and Bioinorganic Consequences"
9:30 am - 9:40 am	Discussion
9:40 am - 10:05 am	"Molecular Mechanism of Transmembrane Transport of Iron"
10:05 am - 10:15 am	Discussion
10:15 am - 10:45 am	Coffee Break
10:45 am - 11:10 am	"Applications of Machine Learning to Metalloproteins"
11:10 am - 11:20 am	Discussion
11:20 am - 11:45 am	"Mn-Based Catalytic Antioxidants Known as Superoxide Dismutase Mimics: Evaluation in Cells: Bioactivity, Quantification, Speciation, Location"
11:45 am - 11:55 am	Discussion
11:55 am - 12:20 pm	"Expanding the Toolbox to Track Metals in Cells: Optical and Vibrational Probes"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Bioinorganic Chemistry in Nature Discussion Leader:
7:30 pm - 7:35 pm	Introduction by Discussion Leader
7:35 pm - 8:00 pm	"Nitrite Reduction by Polynuclear Iron Compounds"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:35 pm	"Abiotic Reactions Catalyzed by Engineered Hemoprotein"
8:35 pm - 8:45 pm	Discussion
8:45 pm - 9:10 pm	"Radical SAM Enzymes: Nature’s Choice for Initiating Radical Reactions"
9:10 pm - 9:20 pm	Discussion
9:20 pm - 9:30 pm	General Discussion
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

The Agouron Institute

The Saltman Lecturer Fund

The Stiefel Young Investigator Fund

American Chemical Society (ACS)

Conference Links

Conference History Bioinorganic Chemistry (GRS) Contribute Financially to This Conference

Conference Fees

Similar Conferences

Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Diversity Funding

Financial assistance is available for qualified applicants through the GRC Carl Storm Underrepresented Minority Fellowship Program. This program provides a grant to underrepresented minority graduate students, postdocs, faculty and scientists to help fund their attendance at their first GRC meeting. Learn more.

Registration Fees

Conferee Single Room:

$1,720.00

Conferee Shared Room:

$1,375.00

Conferee Off-Site:

$945.00

Guest Single Room:

$1,530.00

Guest Shared Room:

$1,185.00

Guest Off-Site:

$755.00

Child 4-12 yrs Shared Room:

$593.00

Child 4-12 yrs Off-Site:

$378.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Additional Fee Info

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