Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Inorganic Nanomaterials in Medicine
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
"Engineered-Surface Metal-Organic Frameworks as Drug Nanocarriers"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Bioorthogonal Catalysis Using Nanoparticle-Embedded Transition Metal Catalysts for Therapeutics and Diagnostics"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Autophagic Silicon Nanoparticles for Targeted Delivery of Therapeutics"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Metal Homeostasis in Health and Disease
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Inhibiting Metal-Mediated Demethylation to Reshape Cancer Epigenetics"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Siderophores and Their Potential Applications as Antimicrobials"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Potentiation of Oncolytic Virotherapy by Vanadium Compounds"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Reprogramming the Chemical Reactivity of Metals in Cancer"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
"Ushering in the Digital Drug Design Revolution with Spherical Nucleic Acid Nanoparticle Conjugates"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Forge Therapeutics: Bioinorganic Directed Drug Discovery"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:25 pm
"From Discovery to Company Formation: Views from a Venture Capital Investor"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Recent Developments in Metallodrugs
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Gadolium Texaphyrins, Platinum and Gold"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Copper Complexes as Anticancer Agents: New Mechanistic Insights"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"A Metal-Containing Drug Repurposed for Neglected Tropical Diseases"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Innovative Metallo-Prodrug Strategies Leading to Multimodal Cancer Therapeutics"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
"Using Synthetic Heparan Sulfate to Treat Acute Liver Injury"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Manganese and Glycosaminoglycans in Tumor Progression: From Cell Migration to Premetastatic Niche Formation"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:25 pm
"Glycans as Ligands in Bioinorganic Chemistry. Chemical and Biological Studies in Metalloglycomics"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Agents for Imaging Applications
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Technetium and Rhenium Complexes with Aromatic Hydrocarbons as π-Ligands: An Entry into Biomimetic Imaging"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"How Chelator Choice Impacts Biodistribution of Radiometal-Labeled Biomolecules"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"From Cell Imaging to Predrug: The Renaissance of Metallosalens in Biological Applications"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Cutting Edge Fluorescence Imaging Strategies for Precise Regulation of Cellular Functions and Localized Theranostics"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Case Studies in Translational Research
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
"Once upon a Time in Vienna: A Story from Ruthenium to Platinum"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Once upon a Time in Vienna: The Power of Activation by Reduction"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Once upon a Time in Vienna: Tumor-Specific Accumulation of Metallodrugs"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Analytical Techniques for Metals in Biological Systems
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Methods for Comprehensive Analysis of Platinum Targets in Yeast and Mammalian Cancer Cells"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Metal Speciation in In Vitro and In Vivo Biological Activities from Drugs to Toxins"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Global Approaches to Metal Speciation: Metallomics"
11:30 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Emerging Proteomics Methods to Elucidate Metallodrugs' Mechanisms of Action in the Cellular Context"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Young Investigator Presentations
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Therapeutic SIMCats: In Pursuit of Catalytic Medicines"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Metal-Chelating Antibiotics and Natural Products"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"A Small Molecule that Transports Iron Promotes Iron Absorption and Hemoglobinization"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Rhenium(I) Complexes as Anticancer Agents: Challenges and Opportunities"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure