Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Stress of Being in a Host
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Persisting in Macrophages"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"How H-NS and the Core Transcriptional Machinery Collaborate to Regulate Foreign Genes"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
"Role of Stressosomes in the Regulation of Listeria Monocytogenes Virulence"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"The Transcriptional and Phenotypic Landscape of Streptococcus Pneumoniae During Infection"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Replication and Nutrient Stress
9:00 am - 9:20 am
"The E. coli “Leucine-responsive Regulatory Protein” Integrates Host and Microbial Stress Signals to Reshape DNA and Gene Expression"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Replication Stalling and Transcription Termination Conflicts Induce the RpoS General Stress Response through the Regulation of iraD by DnaA and SspA"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Predicting the Effect of Gene Expression and Environmental Variation on E. coli Growth Rate"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Expression-Fitness Relationships in Essential Genes"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Regulation of the DNA Damage Checkpoint"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Sound the Alarmone: The role of CdnL in the Caulobacter Stringent Response"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Restraining Rho Termination During Stress"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Exploring Uncharted Territory in Streptomyces Growth and Development"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
"Development and Mechanisms of Pyocyanin Resistance in Staphylococcus aureus"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Adapting to Cell Envelope Stress as a Cooperative Microbial Community"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
"Subversion of Mitochondrial Metabolism Supports Intracellular Bacterial Expansion Inside the Host Cell"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"Cyclic Di-Nucleotide Signaling and Adaptation in Microorganisms"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Role of Translational Fidelity in Bacteria-Host Interactions"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Oxidative, Metal and Antibiotic Stress
9:00 am - 9:20 am
"Metabolic Remodeling in Response to Antibiotic Stress in Mycobacteria"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Bacterial Response and Adaptation to Host-Targeting Chemotherapies Alters Drug Metabolism"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"The Genetics of Antibiotic Function in Acinetobacter baumannii"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Fe-S Cluster-Based Biology and Redox Adaptation"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Bacillus Subtilis Stress Responses"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
"How Drugs and Gambling Promote Antibiotic Resistance Evolution and Drugs to Stop Them"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Universal Protein Chaperone Hsp70 Advances Bacterial Survival During Magnesium Starvation by Inhibiting Protein Synthesis"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Clostridioides difficile Adapts to Iron Stress Through Intracellular Iron Biomineralization"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Polyunsaturated Fatty Acids Potentiate Aminoglycoside Killing of S. Aureus Small Colony Variants"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Energy and Metabolic Stress
7:30 pm - 7:50 pm
"The Effect of Light on Biofilm Metabolism in Pseudomonas Aeruginosa"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Unraveling Lanthanide Transport, Storage, and Usage in Methylorubrum Extorquens"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"TrmB Targets Anaplerotic Enzymes from Diverse Evolutionary Lineages to Regulate Gluconeogenesis in Halophilic Archaea"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Alternative Glycolytic Isozymes Facilitate Glucose Consumption by Pathogens When Metal-starved by the Host"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Regulatory Systems for Stress
9:00 am - 9:20 am
"How C-Di-GMP Controls Progression Through the Streptomyces Life Cycle"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Morphological Coupling Between Coat Assembly and Transcription During Sporulation"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Microcompartment-Related Structures Exhibit Dynamic Behavior"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Coordinate Regulation of Stress Response and Surface Adhesion"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Novel Regulatory Loops for Turning On and Off the RpoS Response"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Characterization of B. burgdorferi Regulatory RNAs Detected by Transcriptome Mapping"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Spontaneous and Triggered Antibiotic Persistence by (p)ppGpp-GTP Antagonism in Bacillus Subtilis"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Regulating Stress Responses From Inside Genes"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Stress of Phage and Mobile Genetic Elements
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Bacterial Sex is Stressful"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:15 pm
"Exploring the Impact of Type III CRISPR-Cas Immunity on Bacterial Variation"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Direct Activation of a Fused Toxin-Antitoxin System by the Major Capsid Protein of Bacteriophages"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
"The Condensin-like Wadjet Defense System Impairs Bacterial Plasmid Transformation by Recognition and Cleavage of Closed-Circular DNA"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Bursting at the Seams: Characterization of a Novel Phage Lysis Gene in Actinophages"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
Late-Breaking Topic
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Proteotoxic and Translational Stress
9:00 am - 9:20 am
"Protecting Nascent Polypeptides from Premature Aging"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"Mapping Functional Regions of Essential Bacterial Proteins with Dominant-negative Protein Fragments"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Making and Breaking Ribosome Dimers"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Pseudomonas aeruginosa Induces Aggregation in the Co-Infecting Pathogen Stenotrophomonas maltophilia"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:00 am
Short Talk Selected from Poster Abstracts
11:00 am - 11:05 am
Discussion
11:05 am - 11:25 am
"Are You Stressed? Functional Roles of Di-Adenosine Nucleotides"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Extraribosomal Role of Hibernation Promoting Factor in Staphylococcus Aureus"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Dual Functions of a Biosynthetic Enzyme (QueE) in tRNA Modification and Bacterial Stress Response"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Adaptor-Mediated Lon Proteolysis in Bacillus Subtilis"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Visualizing the Bacterial Stress Sensing Machinery in Action"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:05 pm
"Long-Chain Fatty Acid Metabolism is Intricately Interconnected to the Cpx Envelope Stress Response"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Building an Outer Membrane – How Stressful!"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:45 pm
"Cold Stress as an Instrument to Elucidate the Unique Role of YhdP in E. coli Cell Envelope Biogenesis"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"How the Environment Shapes E. coli"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure