Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Evolution and Dynamics of Organelles and Their Genomes
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:10 pm
"The Identity Crisis of the Mitochondrion - on Retaining a Bacterial Regulatory Heritage Versus Adaptation to the Host"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Mechanisms of Mutation Rate Variation and Heteroplasmic Sorting in Plant Mitochondrial and Plastid Genomes"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Experimental Endosymbiotic Models to Investigate Molecular Drivers of Chloroplast Evolution"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
"Redesigning the Chlamydomonas reinhardtii Chloroplast Genome"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organelle Gene Expression
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Errors in Mitochondrial Gene Expression"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Coordination of Mitochondrial Gene Expression with Mitoribosome Biogenesis"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Mechanisms of Mitochondrial Promoter Recognition in Humans and Other Mammalian Species"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:05 am
"Involvement of alpha-solenoid proteins and peptidases in gene expression and protein import in organelles: diversity and evolution"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
"Most Dual-Origin Complexes Are Regulated Asynchronously During Chloroplast Biogenesis"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Identification and Characterization of Mitoribosome Interactome in Standard and Oxidative Conditions"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"RNA Flow Analysis Reveals How Differential Turnover, Transcription Termination and Ribosome Engagement Set Mitochondrial Transcript Levels"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Mitochondrial mRNA Structure as a Driver of Leigh Syndrome"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
"Angel2 Phosphatase Activity is Required for Non-Canonical Mitochondrial RNA Processing"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Protein Import, Sorting and Assembly
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Protein Import into Chloroplasts and its Regulation by the Ubiquitin-Proteasome System"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Role of TIM23 in Protein Import and Sorting"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Chloroplast-Localized Translation for Protein Targeting in Chlamydomonas"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"How protein import may have evolved from antimicrobial attack and defence during endosymbiosis"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Organelle Dynamics: Division, Differentiation and Contacts
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Deciphering the Dynamism of Chloroplast Nucleoids"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Targeting Proteins to Mitochondria - the Long and Winding Road"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Mitochondrial Genome Integrity and Inheritance"
11:00 am - 11:10 am
Discussion
11:10 am - 11:20 am
"The ER Membrane Complex (EMC) Can Functionally Replace the Oxa1 Insertase in Mitochondria"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Interorganellar communication sites within plant cells"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"A Unusual Mitofusion is Involved in Mitochondrial Membranes Fusion in Trypanosoma brucei "
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Mitonuclear Translational Control by the Peptide in Mitochondrial Ribosomal RNA"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
"The role of SLC25A46 in mitochondrial fission and fusion through oligomerization of MFN2 and OPA1"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Structure and Function of Organelle Complexes
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Structural Basis of Mitochondrial Inner Membrane Curvature"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Structures of Yeast Respiratory Supercomplexes"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Coordination of Metal Center Biogenesis in Human Cytochrome C Oxidase"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Structure and Assembly of the Mammalian Mitochondrial Supercomplex CIII2CIV"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"Structure and Biogenesis of the Eukaryotic CO2 -Concentrating Organelle, the Pyrenoid"
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Understanding and Correcting Energy Failure in Vulnerable Cells"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Adaptations of C4 Decarboxylases to Their Function in C4 Photosynthesis"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"A Spatial Map of Hepatic Mitochondria Uncovers Functional Heterogeneity and Plasticity at the Tissue Scale"
11:00 am - 11:10 am
Discussion
11:10 am - 11:20 am
"Making a fresh starch: Biochemical regulation of starch granule initiation is distinct in Arabidopsis and wheat"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"DUF3411 Defines a New Class of Plastidial Amino Acid Transport Proteins"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Tales of Mitochondria: How Have the Roles of Mitochondria in C4 Photosynthesis Affected Respiratory Metabolism?"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Agrobacterium-Mediated Transformation of the Plastid Genome"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:15 pm
General Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Proteostasis, Mitophagy and Chlorophagy
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"The Role of Protein Phosphorylation Within the Mitochondrial Matrix in Regulating the Specificity of Mitophagic Degradation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Development of Novel Oral Drug Aiming at Disease-Free Aging"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:35 pm
"A Non-Canonical Role for Mitochondrial Morphogen TMEM11 as an Inhibitor of the Mitophagy Receptor BNIP3"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"In Vivo Trapping of Substrates and Adaptors of the Chloroplast Clp Chaperone-Protease System"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Ubiquitination Acts Inside Chloroplasts to Directly Regulate Photosynthesis"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Signaling and Stress Response
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Probing Excess Light Response Using Photosynthetic Mutants of Chlamydomonas reinhardtii "
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"OMA1 Mediates Local and Global Stress Responses Against Protein Misfolding in CHCHD10 Mitochondrial Myopathy"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Diurnal Cycle in the Green Alga Chlamydomonas reinhardtii at Different Light Intensities"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:05 am
"Spatially Resolved Mitochondrial Phospho-Proteomics in Intact Liver Tissue"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
"An Enigmatic Chloroplast Kinase Interacts With the Chloroplast Ribosomal Assembly Factor, mTERF9 and is Important for Arabidopsis Plant Acclimation to Higher Light"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Altered tRNA Processing Activates the Mitochondrial Unfolded Protein Response"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Mitochondrial Unfolded Protein Response is Essential for Cancer Cell Survival and Represents a Therapeutic Vulnerability"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"The Sensory Plastid is a Discrete Class of Environment-Sensing Plastids That Trigger Epigenetic Phenotypes in Plants"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Organelle Biology Translated into Medicine and Agriculture
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Engineering the Plastid for Higher Photosynthetic Efficiency and Food Security - From Math to Field"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Mitochondria and Degenerative Diseases"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Identification of Differentially Expressed Genes in Friedreich’s Ataxia Patients"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Chloroplast Biotechnology and Synthetic Biology"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure