SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Electron Transfer, Proton Transfer, Role of Water in Proteins |
7:40 pm - 7:55 pm | Discussion Leader: Marilyn Gunner (CUNY, NY, US) |
7:55 pm - 8:20 pm | P. Leslie Dutton (University of Pennsylvania, PA, US)
"Natural Selection and Variance in Engineering Electron Transfer Chains and Oxidation-reduction Catalysis" |
8:20 pm - 8:25 pm | Discussion |
8:25 pm - 8:50 pm | Sharon Hammes-Schiffer (Penn State, PA, US)
"Proton-Coupled Electron Transfer in Proteins: Dynamics and Kinetic Isotope Effects" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | David Beratan (Duke University, NC, US)
"Bridges and Switches: Protein Motion and Electron Transfer" |
9:20 pm - 9:30 pm | General Discussion (Colin Wraight) |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Assembly of Multi-subunit, Multi-cofactor Membrane Proteins |
9:00 am - 9:30 am | Discussion Leader: Sabeeha Merchant (UCLA, CA, US) |
9:30 am - 9:55 am | Michael K. Johnson (University of Georgia, GA, US)
"Iron-sulfur Cluster Biosynthesis" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:25 am | Stuart J. Ferguson (University of Oxford, UK)
"The Thioether Bonds in c-type Cytochromes; the Puzzles of Why and How" |
10:25 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:25 am | H-Georg Koch (Albert-Ludwigs University, Freiburg, Germany)
"Membrane Protein Assembly in Bacteria: Defining the Route from the Ribosome to the Formation of Oligomeric Complexes" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Egbert J. Boekema (University of Groningen, Netherlands)
"Structure of Plant Mitochondrial Supercomplexes by Electron Microscopy" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | General Discussion (Bernd Ludwig) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | F0-F1 ATP Synthase: Structure and Function |
7:30 pm - 7:50 pm | Discussion Leader: Wolfgang Junge (University of Osnabruck, Germany) |
7:50 pm - 8:15 pm | John E. Walker (MRC, Cambridge, UK)
"Inhibitors of ATPase as an Aid to Understanding Function" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Stanley D. Dunn (University of Western Ontario, Canada)
"Structure and Function of the ATP Synthase Peripheral Stalk" |
8:45 pm - 8:50 pm | Discussion |
8:45 pm - 9:10 pm | Paola Turina (University of Bologna, Italy)
"The H+/ATP Ratio and its Subtleties" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion (Wayne Frasch) |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Complex II and Complex IV: Structure-Function and Biology |
9:00 am - 9:15 am | Discussion Leader: Hartmut Michel (Max Planck Institute, Germany) |
9:15 am - 9:40 am | Gary Cecchini (VA Medical Center, CA, US)
"The Heme of Complex II - What is it Good for?" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Marten Wikstrom (University of Helsinki, Finland)
"Proton Translocation by Cytochrome c Oxidase" |
10:10 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:00 am | Discussion Leader: Bob Gennis (University of Illinois, IL, US) |
11:00 am - 11:25 am | Jon Hosler (University of Mississippi, MS, US)
"Subunit III as the Anti-inactivation Component of Cytochrome c Oxidase" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Maik Huttemann (Wayne State University, MI, US)
"Regulation of Cell Respiration through Cell Signaling" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | General Discussion (Roy Lancaster) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mitochondrial Links to Apoptosis, Cancer and Aging |
7:30 pm - 7:50 pm | Discussion Leader: Takao Yagi (Scripps Research Institute, CA, US)
|
7:50 pm - 8:15 pm | Craig B. Thompson (University of Pennsylvania, PA, US)
"The Bioenergetics of Cell Growth" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Paul M. Hwang (NHLBI/NIH, MD, US)
"Cytochrome c Oxidase Regulation by p53" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Lenny Guarente (MIT, MA, US)
"Sirtuins, Disease and Aging" |
9:15 pm - 9:30 pm | General Discussion (Bernard D. Lemire) |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Poster discussion / Workshop sessions |
9:00 am - 10:30 am | Electron Transport and Redox |
| Discussion Leaders: Tony Crofts (University of Illinois, IL, US) & Blanca Barquera (Rensselear Polytech. Inst., NY, US) |
| ATPase |
| Discussion Leader: Stephan Wilkens (SUNY Upstate Medical Univ, NY, US) |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 12:30 pm | Molecular and Cellular Bioenergetics Workshop |
| Discussion Leader: Shelagh Ferguson Miller (MSU, East Lansing, MI, US) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | V-ATPase Structure-Function and Cell Biology |
7:30 pm - 7:50 pm | Discussion Leader: Patricia M. Kane (SUNY Upstate Medical Univ., NY, US) |
7:50 pm - 8:15 pm | Michael D. Forgac (Tufts University, MA, US)
"Structure, Function and Regulation of the Vacuolar ATPases" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Tom H. Stevens (University of Oregon, OR, US)
"Assembly and Sorting of the Yeast V-ATPase" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | G.H. Sun-Wada (Doshisha Women College, Kyoto, Japan)
"Tissue-specific Subunit Isoforms of Proton Pump V-ATPase" |
9:15 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion (Nathan Nelson) |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Complex I and Complex III: Structure-Function and Biology |
9:00 am - 9:15 am | Discussion Leader: Tomoko Ohnishi (University of Pennsylvania, PA, US) |
9:15 am - 9:35 am | Leo Sazanov (MRC, Cambridge, UK)
"The Structures of the Hydrophilic and Membrane Domains of Respiratory Complex I" |
9:35 am - 9:40 am | Discussion |
9:40 am - 9:55 am | Judy Hirst (MRC, Cambridge, UK)
"New Insights into the Iron-sulfur Clusters of Complex I from EPR Spectroscopy" |
9:55 am - 10:10 am | Uli Brandt (University of Frankfurt, Germany)
"Structural and Functional Insights into Mitochondrial Complex I" |
10:10 am - 10:15 am | Discussion |
10:15 am - 10:45 am | Coffee Break |
10:45 am - 11:00 am | Discussion Leader: William A. Cramer (Purdue University, IN, US) |
11:00 am - 11:25 am | Di Xia (NIH/NCI, MD, US)
"Cytochrome bc1 Structures and Implication for Function" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Akhil Vaidya (Drexel University, PA, US)
"Electron Transport in the Minimalist Mitochondrion of Malaria Parasites" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | General Discussion (Carola Hunte) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | From Omics and Imaging to Mitochondrial Frontiers |
7:30 pm - 7:50 pm | Discussion Leader: Britton Chance (University of Pennsylvania, PA, US) |
7:50 pm - 8:15 pm | Vamsi K. Mootha (Harvard Medical School, MA, US)
"Mitochondrial Systems Biology" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Orian Shirihai (Tufts University, MA, US)
"Photoactivatable GFP: a Window into the Social Life of Mitochondria within the Individual Cell" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Terry G. Frey (San Diego State University, CA, US)
"Correlated Light and Electron Microscopy in Four Dimensions Reveals Structural Changes in Mitochondria During Apoptosis" |
9:15 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion (Roger C. Prince) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |