Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Synapse Development and Organization
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:50 pm
"Molecular Underpinnings of Sex-Specific Synapse Development in Central and Peripheral Circuits"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Mechanisms of Neurodevelopment and Synaptic Signalling
5:30 pm - 5:45 pm
"Long-Range Axonal Wiring by Adult Hippocampal Neurons After Transcriptional Programing by Id2"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
"Functional Specificity of Liquid-liquid Phase Separation at The Synapse"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
"Identification of dmPAG Tac2+ Neurons in Regulating Mouse Aggression Behaviors"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"The Essential Role of Latrophilin-1 Adhesion GPCR Nanoclusters in Inhibitory Synapses"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
"Spatially Resolved Single-Cell Analysis Reveals Early Prenatal Specification of Human Cortical Layers and Areas"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
"The Inhibitory Postsynaptic Scaffold as a Controller of Episodic Memory Content and Precision"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cellular and Molecular Mechanisms of Nervous System Disease
9:00 am - 9:15 am
"VAV2 Suppression Mitigates Disease Processes in Models of Diverse Forms of ALS/FTD"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"The Function of TDP43 through The Lens of Protein Interactions"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Investigating the Impact of LRRK2-G2019S on Ultrafast Endocytosis at Hippocampal Presynapses"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Schizophrenia Genetic Risk Converges on Parvalbumin-Expressing Interneuron Wiring"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Nucleotide Dyshomeostasis Contributes to Cognitive Aging and Alzheimer's Disease"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"Circuit-Mediated Vulnerability in SCA1, Its Not Only About Purkinje Neurons"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Novel Tools to Study the Nervous System
1:30 pm - 1:45 pm
"Electrophysiological Mechanisms and Validation of Ferritin-Based Magnetogenetics for Remote Control of Neurons"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
"Developing New Tools to Investigate Neuronal Connectivity of A Novel Myenteric Neuron Class"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
"Identification of Cell Type Specific Enhancers and Evaluation of Cross-Species Conservation of Transcriptomic Cell Types in The Cerebral Cortex"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes