Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Biology of the Endoplasmic Reticulum
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:25 pm
"Mechanism of ER-Associated Protein Degradation (ERAD)"
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:15 pm
"ER-Mitochondria Contact Sites Are Platforms for Morphological Decision Making"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organelle Interactions and Communication
9:00 am - 9:20 am
"Spatial Organization of Lipid Droplets at Organelle Contacts in Yeast and Metazoans"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Function of the Vacuole Mitochondria Contact Site (vCLAMP) Organelle Contact Site"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Lipid Droplet Assembly Factor-1 and Seipin Form a Lipid Droplet Assembly Complex"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"New Routes for Targeting Proteins to Organelles"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Fatty Acid Channeling Drives Autophagic Membrane Formation at Phagophore-ER Contacts During Autophagy"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Countertransport of Lipids at Membrane Contact Sites and Its Role in Membrane Trafficking"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"The Function of VPS13 and Chorein-N Motif Proteins in Lipid Transfer"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Shaping, Fusing and Dividing Membranes
7:30 pm - 7:50 pm
"ESCRT Function in Membrane Repair"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Phenotypic Classification of Early Acting EAPs Using a Novel Disassembly Asymmetry Score Analysis"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The ESCRT Pathway in Cytokinetic Abscission and the Abscission Checkpoint"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Tethering Controls the Functionality of Trans-SNARE Pairing"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Biosynthesis and Quality Control at Membranes
9:00 am - 9:20 am
"Membrane Protein Quality Control: Writing and Reading the Ubiquitin Code in ESCRT-Mediated Protein Turnover"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Phosphorylation of Mitofusin GTPase Domain Regulates Fusion Activity"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"A Novel Translocon for Biogenesis of Multi-Pass Membrane Proteins"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Co-Translational Quality Control of Membrane Protein Biogenesis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Protein Biogenesis at the ER Studied In Situ "
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Structural Basis for pH-Dependent Retrieval of ER Proteins from the Golgi Apparatus by the KDEL Receptor"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Structure of the AAA Protein Msp1 Elucidates Its Mechanism of Extracting Mislocalized Membrane Proteins"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Mechanism of Ca2+ and Sphingomyelin Dependent Protein Secretion"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lipid Homeostasis and Regulation
7:30 pm - 7:50 pm
"Emerging Roles for Phosphoinositide-Binding Proteins in Cell Signaling"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Linking Membrane Architecture and Function by Correlative Microscopy"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The Structural Determinants and Functional Consequences of Transmembrane Protein Affinity for Ordered Membrane Domains"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Lipid-Dependent Signaling at the Ciliary Membrane"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Membrane Specialization in Cells
9:00 am - 9:20 am
"Mechanisms of Vesicle Tethering at the TGN"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Mammalian Retromer Is an Adaptable Plastic Scaffold for Cargo Sorting from Endosomes"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Plasma Membrane Tension Regulates Eisosome Structure and Function"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Quality Control of the Primary Cilia Proteome"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Wnt Signaling Proteins at Dendrite Branch Points Control Neuronal Microtubule Organization"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"ATP-Dependent Membrane Remodeling Links EHD1 Functions to Endocytic Recycling"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Rab GTPase Phosphorylation Blocks Ciliary Hedgehog Signaling in the Brain"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Regulation of Lysosomal mTORC1 Signaling by Inter-Organelle Contacts"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Maintenance of Organelle Identity
7:30 pm - 7:50 pm
"Targeting Proteins to Membrane Contact Sites"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"SNARE Mimicking Factors: A Threat to Membrane Fusion"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Regulation of GTPases at the Golgi Complex"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Activation of the Exocyst Tethering Complex for SNARE Complex Regulation and Membrane Fusion"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Compartmentalisation in the Endosomal System"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Pathogen Manipulation of Host Membranes
9:00 am - 9:20 am
"Viral Exploitation of Extracellular Vesicles for Transmission"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Mixing of Parental Genomes After Fertilization in C. elegans Requires Pronuclear Membrane Fusion that Generates a Novel Membrane Structure"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"AP-1B Facilitates Endocytosis During Cell Migration"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Structural Basis for Selective Endosomal Sorting by BAR Domain-Containing Sorting Nexins"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Lessons Learned from Intracellular Bacteria: How to Remodel Rhe Host Cell"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Regulation of Endolysosomal Membrane Permeability in Dendritic Cells"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"CRISPR Screening Reveals an ER Resident Antiviral Protein that Suppresses Flavivirus Replication"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Global Approaches to Understanding Membrane Biology"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Visualizing Cells and Molecules in Context
7:30 pm - 7:50 pm
"Cryo-Electron Tomography: The Cell Biology that Came in from the Cold"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Native ESCRT Dynamics as Revealed by Lattice Light Sheet Imaging of CRISPR/Cas9-Modified Human Cell Lines"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Rapid Protein-Specific Nanoscale Imaging of Neural Circuits Across Cortical Columns and Whole Brains"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Sec Bodies Form in Response to Sodium Stress and Ire1 Activation, both Triggered by Nutrient Starvation"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"New Approaches for Imaging the Spatial and Temporal Dynamics of Organelles and Molecules Within Cells"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure