Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Biogenesis and Function of Membranes
7:40 pm - 7:50 pm
"Translocation In and Out of Organelles"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:30 pm
"Control of Secretion at the Immunological Synapse"
8:30 pm - 8:45 pm
Discussion
8:45 pm - 9:15 pm
"The Biogenesis of Multipass Membrane Proteins"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Mechanisms Driving Lipid Droplet Biogenesis during Adipocyte Differentiation"
9:25 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Size Matters: Unveiling the Unique Exocytosis Mechanism of Large Vesicles in Exocrine Tissues"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"Regulation of COPI Vesicle Fission by Short Lipids Transferred through ER-Golgi Membrane Contact"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
"Tethering Fat: Lipid Droplet-Organelle Contact Sites"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:15 am
"Lipid Transport at Organelle Contact Sites"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Intrinsically Disordered Regions in Sec24 Paralogs Tune COPII Vesicle Size and Occupancy"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Two RNA-Binding Proteins Mediate the Sorting of miR223 from Mitochondria into Exosomes"
11:50 am - 11:55 am
Discussion
11:55 am - 12:10 pm
"Function of ER Membrane Contact Sites"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metabolism and Signaling at Membranes
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:50 pm
"Metabolic Control of TORC1"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Mechanisms of Cellular Response to Stress"
8:15 pm - 8:25 pm
Discussion
8:25 pm - 8:40 pm
"Metabolism Control at the Lysosome"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Biogenesis of Peroxisomes: From Yeast to Man"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Growth Factor Induced Desialylation for the Fast Control of Endocytosis"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Protein Biogenesis and Quality Control at Membranes
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"The Defective for SREBP Cleavage (Dsc) Ubiqutin Ligase Complex Mediates Membrane Quality Control for Golgi and Endosomes"
9:25 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Competition for Calnexin Binding Regulates Secretion and Turnover of Misfolded GPI-Anchored Proteins"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"The Role of UFMylation in 60S Ribosomal Subunit Recycling"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
"An ERAD-Independent Role for Derlin Dfm1 in Regulating Sphingolipid Metabolism"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:15 am
"How Mitochondria Control Cellular Protein Homeostasis"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Role of Ubiquitin Ligases in Peroxisome Homeostasis"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Mapping the ER-Mitochondria Contact Site Proteome Uncovers New Players in Mitochondrial Homeostasis"
11:50 am - 11:55 am
Discussion
11:55 am - 12:10 pm
"Organized Aggregation of Mitochondrial Proteins as a Strategy to Protect Cellular Proteostasis"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lipid Homeostasis at Membranes
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:50 pm
"The role of Pex30-containing complexes in linking the ER to multiple organelles"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Roles of ER-PM Cross Talk and the PI Kinase-TORC2 Signaling Nexus in Cell Integrity"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Mechanism of Secretory Granule Biogenesis"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Triggering Neutral Lipid Condensation Within the ER Membrane"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Membrane Remodeling, Fission and Fusion
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Mechanisms Underlying the Exquisite Regulation of Neurotransmitter Release"
9:25 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Reconstituted Vacuole Fusion; Updating the Membrane Fusion Paradigm"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"Exocyst Undergoes Multiple Conformational Changes to Regulate SNARE Binding, Complex Formation and Fusion"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
"Membrane Remodeling at Endosomes and Lysosomes"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:15 am
"Role of AP-1 Isoforms in Recycling Endosome Biogenesis and Polarized Sorting"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Recruitment of the SNX17-Retriever Recycling Pathway Regulates Synaptic Function and Plasticit"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"An Inside Job: A Mitochondrial Intermembrane Space Protein Facilitates Completion or Organelle Division"
11:50 am - 11:55 am
Discussion
11:55 am - 12:10 pm
"Electron Microscopy in Membrane Research"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Disease, Infections and Treatments
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:50 pm
"Evolution of the Outer Mitochondrial Membrane during Infection"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Legionella Hijacks Host Cell Peroxisomes for Replication Vacuole Membrane Expansion and Integrity"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:30 pm
"The Invisible Network: How Extracellular Vesicles Help Malaria Parasites Thrive and Survive"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
"Ceramide-Dependent Regulation of Mitochondrial Function in Metabolism"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:20 pm
"Organelle Degradation in the Eye Lens"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Mechanisms of Organelle Identity
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Oocytes Sequester Aggregated Proteins in Degradative Super-Organelles"
9:25 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Cell Structure Organization and Polarized Trafficking"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"Molecular Role of Tepsin in Membrane Trafficking and Autophagy"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
"Mitochondrial Remodeling During Nutrient Stress"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:15 am
"Transport Vesicle Targeting to Membranes"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Tether: SNARE Collaboration in Membrane Trafficking"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"P4-ATPase Control over PI4P Membrane Asymmetry and Neomycin Resistance"
11:50 am - 11:55 am
Discussion
11:55 am - 12:10 pm
"Mitochondria, Metabolism, and Cellular Decisions"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Novel Techniques in Molecular Membrane Biology
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 7:55 pm
"Membrane Remodeling in the CO2-fixing Organelle, the Pyrenoid"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
"Flexible Protein Networks Organize and Remodel Membranes During Clathrin-Mediated Endocytosis"
8:15 pm - 8:25 pm
Discussion
8:25 pm - 8:40 pm
"Peptide Delivery Across Membranes"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Structural and Functional Analysis of Sphingolipid Metabolism Enzymes"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Spatial Map of the Human Proteome from Systematic Immuno-Capture of Native Organelles"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure