Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
The Biological Genesis of Motion
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
"How Is Integrated Tissue Architecture Established? Lessons from Body Axis Elongation in Vertebrates"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Hox Genes Distinguish Long from Short Bones: Origins of the Wrist and Ankle"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Movements in Morphospace: How Are Shape and Variation Generated in the Embryonic Face?"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Molecular Energetics and Control
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Muscle Signaling to Other Tissues: Bone and Beyond"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Metabolic Regulation of Skeletal Cells"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Cellular Senescence in Carpal Tunnel Syndrome: Restoring Function and Mobility"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Implications of Cell Senescence for the Aging Skeleton"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Bone and Brain Communications: Regulation of Appetite"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Sensory Nervous System Impact on Subchondral Bone Pathology in a Murine OA Model"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cellular Organization and Behavior
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Meniscus Morphogenesis: Development in Motion"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Making Cartilage: Lessons (Not) Learned"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Skeletal Stem Cell Contributions to the Mechanoadaptation of Bone: Direct and Indirect Biophysical Regulation"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Macrostructural Musculoskeletal Elements
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Functional Adaptation of the Maternal Skeleton to Pregnancy and Lactation"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Menisci and Their Ligamentous Attachments in Health and Disease"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Quantifying the Mechanical Environment Throughout Bone Repair: An Implantable Strain Sensor Platform for Non-Invasive Monitoring"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Muscle Force Production Across the Agespan"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Insights into Mechanisms Underlying Spontaneous, Early Onset Intervertebral Disc Degeneration"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Central and Peripheral Neurological Control Systems
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Autonomic Regulation of Bone Remodeling"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Neuropeptide Regulation of Skeletal and Muscular Responses to Altered Energy Balance"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Peripheral Mechanisms of Joint Nociception"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"How Does Joint Injury Lead to Osteoarthritis, Dysfunction and Disability?"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Ectopic Calcification of the Spine: The What, Where and Why of Diffuse Idiopathic Skeletal Hyperostosis"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Lifting the Breaks on Bone Shape"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Role of Bone-Derived TGF-Beta on Muscle Function and Glucose Metabolism"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Atrogenes as Common Mediators of Glucocorticoid-Induced Bone and Muscle Atrophy and Weakness"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
The Restoration of Musculoskeletal Function
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Bridge-Enhanced ACL Repair: From Concept to Clinical Trial"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"Functional Restoration Following Complex Musculoskeletal Trauma"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Biologically Inspired Concepts Guiding Lower-Limb Exoskeleton Design"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Perfecting Musculoskeletal Coordination
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Perfecting Cellular Motion, Promoting Repair"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Use of Regenerative Peripheral Nerve Interfaces for Closed Loop Neural Control of Prosthetics"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Functional Integration of a Tissue Engineered Intervertebral Disc and Translation to a Large Animal Model"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"A Gene Therapeutic Approach to Inhibiting Articular Inflammation and Restoring Joint Function"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Biological and Biomechanical Studies of Human Muscle Contractures"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Reconsidering the Origin of the TMJ Articular Disc"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: The Musculoskeletal System and the Machine
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:45 pm
"Wounded Warfighters Deserve More than a Hook on the End of a Stick: Moving Toward Restoring Form and Function"
8:45 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure