Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Health Equity in Musculoskeletal Science
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:15 pm
"Sex/Gender Differences in the Diagnosis of Pain"
8:15 pm - 8:25 pm
Discussion
8:25 pm - 8:50 pm
"Partnering with Community Based Organizations to Increase Genetic Diversity in the Pediatric Skeletal Muscle Cell Atlas"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Exploring Intersectionality in Motion Analysis and Motor Control"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Impact of Aging on Musculoskeletal Health
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Mediators of Youthfulness in Skeletal Muscle"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Endogenous Glucocorticoids and Their Receptors in Skeletal Aging"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"A Deep Learning Model to Map Osteocyte Networks Can Successfully Distinguish Between Young and Aged Bone"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Non-Pharmacological Strategies to Maintain Skeletal Muscle Mass and Function in Later Life"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"I Really Gotta Get Out More: A First Step Out of the Lab to Study Older Adult Falls in the Real World"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Multiscale Biomechanics and Mechanobiology
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Mechanobiology of Bone Development and Repair"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Predicting Disc Failure: A Finite Element Modeling Approach"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Treatment of Meniscal Tear: Outcomes of Mechanically-Focused Interventions on a Pain Syndrome of Uncertain Origin"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Multi-Modal Imaging to Assess Musculoskeletal Health
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Imaging of Osteoarthritis: Insights and Open Questions"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Can We Predict Outcomes of Joint Disease by Imaging Cartilage Biomechanics?"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Radiomics-Based Ultrasound Image Analysis for Evaluation of the Thoracolumbar Fascia in Patients with Low Back Pain"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"The Power of Synchrotron-Based Imaging for Unraveling Structure-Function Relationships in Musculoskeletal Tissues"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"I've Looked at Bones from Both Sides Now. Somehow, I Really Don't Know Bones at All"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Defining the Spatial Relationship and Interactions Between Different Tendon Compartments with Combined in situ Multiphoton Imaging and scRNA-Sequencing"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Impact of Spaceflight on Musculoskeletal Health
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Interventions to Preserve Musculoskeletal Health During Spaceflight"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Countermeasures to Protect Gait, Performance and Joint Health in Rodents During Spaceflight"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Impact of Space Travels on Bones: Our Skeleton Adapts to the Conditions of Space Flight but the Return to the Earth is Challenging"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Musculoskeletal Tissue Regeneration
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"From Feedback to Function: Understanding Proprioception's Role in Musculoskeletal Biology"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Cellular Dynamics of Skeletal Muscle Regeneration"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"The Role of Joint Motion as a Mechanical Force in Tendon Development and Wound Healing"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Designing Hybrid Photopolymeric and Degradable Biomaterials for Musculoskeletal Regeneration"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Understanding the Development of Orthobiologic Products"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"A Novel Role for CXCL16 in Joint Inflammation and Nociception"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chronic Joint Pain and Lessons from the Knee, Spine and TMJ
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Developing More Representative and Replicable Small Animal Models of Low Back Pain"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Pain in Different Models of TMJ-OA"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Exploring the Utility of Social Vulnerability Indices to Better Understand and Address Disparities in Osteoarthritis Pain Mechanisms and Outcomes"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Genetic Regulation of Musculoskeletal Disease
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Are Sex Differences in Chondrocyte Mechanoresponse a Link to Sex Disparities in Osteoarthritis?"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Potential Mechanisms of Idiopathic Condylar Resorption of the Temporomandibular Joint"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"A New Mouse Model to Understand Pathogenesis of Heterotopic Ossification in Tendon"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Regulation of Tendon Regeneration"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Systems Genetics Approaches to Unravel the Genetics of Osteoporosis"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Bone Loss and Bone Marrow Dysregulation in the Keratinocyte-Specific Tie2 (KC-Tie2) Mouse Model of Psoriasis"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Computational Methods and Big Data in Musculoskeletal Health
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Multi-Omic Profiling in Osteoarthritis"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Deciphering Cellular Atlases for Skeletal Tissues"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Machine Learning-Based Analysis of Cells and Tissues following Joint Injury"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure