Causes and Consequences of Mutagenesis Across Species

The 2024 Gordon Research Conference on Mutagenesis will focus on the underlying causes and consequences of mutations. The genomes of all organisms are consistently under attack by both endogenous and endogenous mutagens, which can change the genetic code. These changes can cause various diseases such as cancer and antimicrobial resistance development. One important feature of the conference will be bringing together of scientists studying a wide range of questions in the field of mutagenesis and are employing diverse range of cutting-edge approaches across various species.

The conference will focus on the fundamental molecular and genetic mechanisms that drive various genome alterations. The meeting will explore the physiological and pathological consequences of mutagenesis in human health, antibiotic resistance development, adaptive and innate immunity, neurodegenerative disease, and cancer. The major focus of the meeting will be to explore how major processes such as DNA replication and transcription contribute to mutagenesis. Furthermore, the inherent properties within the DNA itself such as sequence context or secondary structures that make certain regions of the genome more susceptible to mutagenesis and genetic alterations will be discussed. The conference will include talks by established and young investigators that are leaders in the field, as well as talks selected from submitted abstracts. The conference will also include extensive poster sessions coupled with ample time for discussion and networking between participants at all career stages in an inclusive and diverse atmosphere.