Sunday
2:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Viruses, Cancer and Stem Cell
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
"Why Do Viruses Cause Cancer?"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
"Normal and Neoplastic Stem Cells"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
EBV Infection and NPC Pathogenesis
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"EBV Genome Sequence Variation: Geography, Function and Disease"
9:35 am - 9:50 am
Discussion
9:50 am - 10:20 am
"How EBV Prevails During Productive Infection"
10:20 am - 10:35 am
Discussion
10:35 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:20 am
"Regulation of Host Signaling Pathways by EBV miRNAs"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"NPC Epigenetic Landscapes and Super-Enhancers"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Nasopharyngeal Carcinoma Susceptibility Gene TNFRSF19 Inhibits TGFβ Signaling and Promotes Tumorigenesis"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Genome Sequencing Analysis Identifies Epstein-Barr Virus Subtypes Associated with the Risk of Nasopharyngeal Carcinoma"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation of Lytic and Latent EBV Infection
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:05 pm
"Differentiation-Dependent Lytic EBV Reactivation in Epithelial Cells"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:45 pm
"New Functions for EBV Proteins in Manipulating Cellular Processes Important for Cancer"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"The Key Cellular Factors in EBV Infection of Epithelial Cells"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Risk Factors and Novel Markers for NPC
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Genetic Predisposition of Nasopharyngeal Carcinoma: Evidence from GWAS and Sequencing Studies"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Application of Plasma EBV DNA Assay in Daily Practice of NPC Management"
9:55 am - 10:05 am
Discussion
10:05 am - 10:35 am
"Plasma EBV DNA for Screening Nasopharyngeal Carcinoma"
10:35 am - 10:45 am
Discussion
10:45 am - 11:10 am
Coffee Break
11:10 am - 11:40 am
"New Insights in NPC Detection Utilizing Circulating Tumor Cell Enumeration and NGS Analysis"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
"Circulating Tumor DNA: Detection and Applications in Curable Cancers"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
2:00 pm - 4:00 pm
Poster Session
4:00 pm - 6:00 pm
Molecular Profiling of NPC
4:00 pm - 4:05 pm
Introduction by Discussion Leader
4:05 pm - 4:25 pm
"Acquired Genomic Changes in Nasopharyngeal Carcinoma"
4:25 pm - 4:35 pm
Discussion
4:35 pm - 4:55 pm
"Genetic Susceptibility in Nasopharyngeal Carcinoma"
4:55 pm - 5:05 pm
Discussion
5:05 pm - 5:35 pm
"Translational Aspects of DNA Methylation in Cancer"
5:35 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"The M81 Epstein-Barr Virus Associated RNA2 Enhances CXCL8 Production and Spontaneous Virus Lytic Replication in Primary B Lymphocytes"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 7:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Tumor Microenvironment of NPC
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Galectin-9 and Other Factors of Immune Escape in NPC Tumor Microenvironment: How to Bring Them Under Control?"
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
"A Role of Bacterial Co-Infection in the Pathogenesis of NPC?"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:10 am
"A Novel Mechanism of Induction of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-Positive Epithelial Malignancies Through Intracellular Iron Chelation"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Are Exposure to Sunlight, Dietary Vitamin D Intake, Serum and Genetically Derived 25-Hydroxyvitamin D Risk Factors of Nasopharyngeal Carcinoma (NPC)?"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"ISNLx Regulates Cellular Metabolic Reprogramming and Is a Potential Therapeutic Target for Nasopharyngeal Carcinoma"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Epstein-Barr Virus-Encoded LMP1 Reprograms Glucose Metabolism to Drive Cell Motility Through mTORC2/PDHE1α-Mediated Histone Acetylation in Nasopharyngeal Cells"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Patient-Derived Cell Models and Next Generation Living Biobanks (NGLB) for Precision Medicine"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"NPC Strip G: Rapid Test Strip Detecting IgG Against EBV Antigens in NPC"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Challenges and Novel Approaches in NPC Treatment
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Role of Chemotherapy in NPC: Not Novel, but Still Challenging"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Comprehensive Treatment Strategy in Locoregionally Advanced Nasopharyngeal Carcinoma"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Challenges and Novel Approaches in Radiotherapy for Nasopharyngeal Carcinoma"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Development of an EBNA1 Inhibitor for the Treatment of NPC: Toward First-in-Human Studies"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
"Immune and Other Biomarkers of Resistance to Anti-PD1 Therapy in NPC"
9:35 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Adoptive T Cell Therapy for NPC: Immune Correlates to Immune Contexture"
10:15 am - 10:25 am
Discussion
10:25 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
"The NPC Immunotherapy Landscape"
11:10 am - 11:20 am
Discussion
11:20 am - 11:45 am
"Cellular Immunotherapy for Nasopharyngeal Cancer: Learning from the Past for a Better Tomorrow"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Immune Checkpoint Inhibitor in the Treatment of Nasopharyngeal Carcinoma: A Clinical Overview"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Keynote Session: Future Perspectives in NPC Research and Treatment
4:00 pm - 4:05 pm
Introduction by Discussion Leader
4:05 pm - 4:45 pm
"Beyond Targeting Oncogenes: Future Anti-Cancer Strategies"
4:45 pm - 5:00 pm
Discussion
5:00 pm - 5:40 pm
"The Future of NPC Research: Opportunities and Challenges"
5:40 pm - 5:55 pm
Discussion
5:55 pm - 6:00 pm
Closing Remarks
6:00 pm - 7:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure