Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Chemical Synthesis to Unlock Natural Product Potential
Discussion Leader: Jeff Kerkovius (Neurocrine Biosciences, United States)
3:45 pm - 4:20 pm
Louis Barriault (University of Ottawa, Canada)
"Sculpting Simplicity: Navigating the Twisties in Total Synthesis of Natural Products"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Natural Product Discovery, Biosynthesis and Bioactivity
Discussion Leader: Christiana Aruwa (Durban University of Technology, South Africa, South Africa)
7:30 pm - 7:50 pm
Neil Grenade (Queen's University, Canada)
"Uncovering Convergent Evolution in the Biosynthesis of Bipyrrolic Natural Products"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
Favour Achimba (Graduate Center/Hunter College, City University of New York, United States)
"Characterizing the Activity and Function of Transient Receptor Potential Channels in Liver Tumor Cells Using New Terebrid Snail Venom Peptide"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
Yaoyu Ding (King's College London, United Kingdom)
"Rapid Peptide Cyclisation Provides Insight into the Structural Logic Encoded in Non-Ribosomal Peptide Synthetases"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
Ryosuke Hirozumi (Tohoku University, Japan)
"Synthetic Studies for Elucidation of Saxitoxin Biosynthesis"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Emebet Getaneh Damessa (Adama Science and Technology University, Ethiopia)
"Exploring Medicinal Plants from Ethiopian Flora: Isolation, Characterization, and Bioactivity Assessment of Natural Compounds"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Modification and Total Synthesis of Complex Natural Products
Discussion Leader: Shambhu Chandra (University of British Columbia, Canada)
9:00 am - 9:20 am
Luca McDermott Catena (UCLA, United States)
"Strain-Promoted Reactions of Anti-Bredt Olefins"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
Carly Schissel (University of California, Berkeley, United States)
"Post-Translational Acyl Rearrangement in Ribosomal Products"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
Brandon Alexander (Yale University, United States)
"An Oxidative Photocyclization Approach to the Synthesis of Securiflustra Securifrons Alkaloids"
10:10 am - 10:15 am
Discussion
10:15 am - 10:35 am
Colin Tichvon (University of Michigan, United States)
"Synthesis of Bufadienolide Steroids via Late Stage Singlet Oxygen Oxidation/Rearrangement Approach"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Jiaqi Li (University of Melbourne, Australia)
"Total Synthesis of Nargenicin A1"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Careers in Complex Molecule Synthesis
Discussion Leader: Linna An (University of Washington, United States)
1:30 pm - 2:30 pm
Panel Discussion
Careers in Complex Molecule Synthesis
Cheryl Hayward (Pfizer, United States)
Dirk Trauner (University of Pennsylvania, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes