Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm
Keynote Session: Astrocyte-Microglia Crosstalk Balance Synapse Formation and Elimination During Development
Discussion Leader: Luuli Tran (University of Colorado - Anschutz Medical Campus, United States)
3:15 pm - 3:50 pm
Cagla Eroglu (Duke University Medical Center, United States)
"Astrocyte-Microglia Crosstalk Balance Synapse Formation and Elimination During Development"
3:50 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Cellular Interactions that Sculpt the Nervous System / Spatiotemporal Mechanisms of Neuronal Diversity
Discussion Leaders: Maheva Andriatsilavo (Paris Brain Institute, INSERM, CNRS, France), Prithviraj Rajebhosale (NIH, United States) and Ya'el Courtney (Harvard University, United States)
5:30 pm - 5:45 pm
Harmony Fong (University of Calgary, Canada)
"Investigating the Developmental Impact of Hypothalamic Tanycytes"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:05 pm
Liam Hallada (SJ Graduate School, United States)
"Junctional Adhesion Molecule (JAM)-C Recruitment of Pard3 to Cell Contacts Initiates Neuron-Glia Recognition and Layer-Specific Cell Sorting in Developing Cerebella"
6:05 pm - 6:10 pm
Discussion
6:10 pm - 6:25 pm
Ryan Leung (Murdoch Children's Research Institute, Australia)
"Transcriptional Regulation of Neural-Glial Fate Switch in the Developing Ventral Forebrain Orchestrated by Homeobox Transcription Factors"
6:25 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Steven Decker (University of California Davis, United States)
"Let-7 Regulates Cortical Neuron Migration by Targeting Rbx2"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Mireia Rumbo (Universitat Pompeu Fabra, Spain)
"CXCL14 is a Key Chemokine Involved in Axon Guidance of Pioneer Axons of the Statoacoustic Ganglion"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Emma Thornton-Kolbe (University of Michigan Ann Arbor, United States)
"Promiscuous Wiring of an Expansion Layer via Variable Spatial Sampling of an Orderly Array"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Neural Circuit Diversity, Behavior, and Disease Models
Discussion Leaders: Emma Thornton-Kolbe (University of Michigan Ann Arbor, United States), Ying Zhang (The Francis Crick Institute, United Kingdom) and Harris Kaplan (Harvard University, United States)
9:00 am - 9:15 am
Rio Salazar (The University of Chicago, United States)
"Huckebein is Required for DIP-a Expression and Target Recognition in the Drosophila Neuromuscular Circuit"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Begüm Aydin (The Rockefeller University, United States)
"Microbiota-Induced Cellular Plasticity in the Enteric Nervous System"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Najia Elkahlah (University of Michigan, United States)
"Intersecting Roles for Lineage and Sex in the Development of Innate Behavior Circuits"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Arjun Bharioke (Institute of Ophthalmology Basel (IOB), Switzerland)
"Layer 5 Pyramidal Neurons Assemble into Active Embryonic Circuits Perturbed by Autism-Associated Mutations at the Inception of Neocortex in Living Embryos"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Tery Yun (DGIST, South Korea)
"Single-Cell Transcriptomic Analysis Reveals Differential Proportions of Neuronal Subtypes Correlated with Swimming Patterns"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Marie Payne (UCLA, United States)
"Hyperoxia and Flow Reduce Metabolic Stress and Accelerate Neural Maturation in Brain Organoids"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Neural Development Across Evolution
Discussion Leader: Shreyas Suryanarayana (Duke University, United States)
1:30 pm - 1:45 pm
Sumin Jang (Columbia University, United States)
"Species-Specific Progenitor Domain Extends Neurogenic Timeline and Increases Motor Neuron Production in Humans"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Rafael Soler Ortuño (Institute of Neuroscience - CSIC / UMH, Spain)
"Genetic Mechanisms Regulating Neurogenic Modes in the Cerebral Cortex Across Amniote Evolution"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Aleksandra Recupero (Columbia University, United States)
"Role of Species-Specific Synaptic Maturation Timing in Cortical Circuit and Behavioral Development"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes