| SATURDAY |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Keynote Session |
| Discussion Leaders: Ramon Trullas (CSIC/CIBERNED) and Petar Podlesniy (CiberNed) |
| 3:15 pm - 3:45 pm | Elizabeth Jonas (Yale University)
"Role of Mitochondrial ATP Synthase in Permeability Transition and Synaptic Plasticity: Two Sides of the Same Coin?"
|
| 3:45 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Homeostasis in Neurological Disease: From Gene Expression to Mitochondria |
| Discussion Leader: Lorena Saelices Gomez (University of California, Los Angeles) and Orly Lazarov (UIC) |
| 5:30 pm - 5:50 pm | Anna Emde (Weizmann Institute of Science)
"Hijacked Stress-Granule Formation Leads to Global Down-Regulation of miRNAs in Amyotrophic Lateral Sclerosis"
|
| 5:50 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:20 pm | Celine Huynen (University of Liege)
"Role of Non-PolyQ Regions on the Different Steps of the Amyloid Fibril Formation Process by PolyQ Proteins"
|
| 6:20 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:50 pm | Laura Haas (Yale University, School of Medicine)
"The Interaction of Brain Cellular Prion Protein with Metabotropic Glutamate Receptor 5 is Regulated by Endogenous Ligands and Therapeutic Molecules"
|
| 6:50 pm - 7:00 pm | Discussion |
| 7:00 pm - 7:20 pm | Courtney Lane-Donovan (University of Texas Southwestern Medical School)
"Reelin Protects Against Aβ-Mediated Memory Impairment"
|
| 7:20 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Aging and Age Related Disease |
| Discussion Leaders: Jongkyun Kang (Brigham and Women's Hospital) and Michael Ward (UCSF Memory and Aging Center) |
| 9:00 am - 9:20 am | Rosalia Ortega (Univeristy of Texas at El Paso)
"Mapping Glycinergic Circuitry in the Nigrostriatal Pathway"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Tatyana Shelkovnikova (Cardiff University)
"Dysfunction of Paraspeckle Proteins as a Possible Pathogenic Factor in ALS"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Sanghun Lee (Brigham and Women's Hospital)
"γ-Secretase in Hippocampal Schaffer Collateral and Mossy Fiber Synapses" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | General Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Treatment of Neurological Disease |
| Discussion Leaders: Peter Tsvetkov (Whitehead Institute) and Amantha Thathiah (Catholic University of Leuven/VIB) |
| 1:30 pm - 1:50 pm | Arnaldo Parra (Universitat Autonoma de Barcelona)
"Crtc1 Nuclear Translocation Is Critical for Hippocampal-Dependent Associative Memory"
|
| 1:50 pm - 2:00 pm | Discussion |
| 2:00 pm - 2:20 pm | Florian Plattner (University of Texas Southwestern Medical School)
"Memory Enhancement by Targeting NR2B Cell Surface Regulation"
|
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
