Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Exploring the Chemistry and Molecular Biology of Nitric Oxide and Sulfur Species
3:45 pm - 3:55 pm
"Labile NO-Ferroheme Specific Detection In Vitro and Ex Vivo Plasma"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"The Function of Sulfite Oxidase in Mitochondrial Supersulfide Metabolism"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Nitrite Reductase-Like Activity of Bovine Serum Albumin Mediated by Sodium Ascorbate"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Discovery to Therapy: Nitric Oxide and Sulfur Species in Clinical Application
7:30 pm - 8:00 pm
"Keynote Talk: It’s just an ‘N’ and an ‘O’. How Difficult Can It Be?"
8:00 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Novel Ubiquinone-Based Small Molecule Nitroalkene Inhibits Ferroptosis in Parkinson's Disease"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Coping with Thin Air: Physiological Responses and Adaptations to Environmental Hypoxia"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"The Na+/I- Symporter as a Nitrate Transporter in Salivary Glands"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Exploring the Clinical Role of Reactive Sulfur Species in Tumour Hypoxia"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Increased Anion Exchanger-1 (Band 3) on the Red Blood Cell Membrane Accelerates Scavenge of Nitric Oxide Metabolites and Predisposes Hypertension Risks"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Nitric Oxide Signaling Across Physiology
9:00 am - 9:10 am
"Effect of eNOS in RBCs on the Distribution of NO Metabolites After Oral Administration of 15 N-Labelled Nitrate"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Exogenous and Diet-Derived Formation of DNIC Prevents Cardiometabolic Dysfunctions Induced by a Western Diet in Mice"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"From the Culture Dish to Asthma: Redirecting Myeloid Cell Substrate Utilization with Nitro-oleic Acid"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Cardioprotective Metabolic Reprogramming Regulated by the Denitrosylase S-Nitroso-CoA Reductase 2"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Autophagy Regulation by Sulfide Metabolic Pathway in Ischemic Peripheral Vascular Remodeling"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Thioredoxin: A Key Regulator of Nitric Oxide in Autism Spectrum Disorder"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Mechanical Force Enhances NO-Induced cGMP Generation in Vascular Smooth Muscle Cells"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Loss of NO-GC in Periostin+ Myofibroblasts Accelerates Ang II-Mediated Cardiac Remodeling"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: How to Build a Scientific Career
1:30 pm - 2:30 pm
Panel Discussion
Career Opportunities in Science
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes