Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Gene Delivery and Miniature Microscopy for Functional Circuit Interrogation
Discussion Leader: Karl Deisseroth (Stanford University, United States)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
Ilana Witten (Princeton University, United States)
"Mapping Learning Algorithms onto Brain Circuitry"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
Denise Cai (Icahn School of Medicine at Mount Sinai, United States)
"Memory Stability and Flexibility Across the Lifetime"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Optics, Genetics, and Optogenetics
Discussion Leader: Olivia Masseck (University of Bremen, Germany)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Elena Govorunova (McGovern Medical School, University of Texas Health, United States)
"The Development of Channelrhodopsin-Based Inhibitory Optogenetic Tools"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Shiqiang Gao (University Würzburg, Germany)
"Chromophore-Independent Channel Activity of Channelrhodopsins"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Tommaso Fellin (Istituto Italiano di Tecnologia, Italy)
"Aberration Correction in GRIN Microendoscopes through Three-Dimensional Printed Polymer Microlenses"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
J. Simon Wiegert (University Heidelberg, Germany)
"A New Look at an Old Concept: Optogenetic Investigation of Brain Stem-Driven Pupil Dynamics"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Christiane Grimm (Vision Institute, Paris, France)
"Manipulating and Observing Neural Activity with Scanless Two-Photon Illumination"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Janos Fuzik (Karolinska Institute, Dept. of Neuroscience, Sweden)
"Voltage-Seq: All-Optical Postsynaptic Connectome-Guided Single-Cell Transcriptomics"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Thiago Arzua (Columbia University, United States) and Moriel Zelikowsky (University of Utah, United States)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Optical Readouts of Neural Activity
Discussion Leader: Li Ye (Scripps Research Institute, United States)
6:00 pm - 6:20 pm
Tommaso Patriarchi (University of Zurich, Switzerland)
"Next-Generation Optical Tools to Probe Neuromodulators In Vivo"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
Christina Kim (University of California, Davis, United States)
"Molecular Probes for Activity-Dependent Protein Tagging in the Brain"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Ryohei Yasuda (Max Planck Florida Institute for Neuroscience, United States)
"Imaging and Manipulating Synaptic Plasticity"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Kiryl Piatkevich (Westlake University, China)
"New Molecular Tools for Scalable Recordings of Neuronal Activity"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Yaroslav Sych (Institute of Cellular and Integrative Neuroscience, France)
"Reward Experiences Shape Norepinephrine Release During Task-Learning and Consolidation During Sleep"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Brain-Body Optogenetics
Discussion Leader: Anna Beyeler (INSERM U1215, France)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Yoav Livneh (Weizmann Institute of Science, Israel)
"Non-Invasive Gut Optogenetics Reveal Interoceptive Sensations and Predictions"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Ritchie Chen (University of California, San Francisco, United States)
"Heartfelt Emotions: How Cardiac Sensations Influence Affective Behavior"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Sung-Yon Kim (Seoul National University, South Korea)
"How Does Ingestion Rapidly Shape Motivation?"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
Nadine Gogolla (Max Planck Institute of Psychiatry, Germany)
"Neuromodulation in the Visceral Insular Cortex Gates Fear Extinction Balance"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Sarah Stern (Max Planck Florida Institute, United States)
"Insular Cortex Circuits Mediating Flexible Feeding Behaviors"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Minel Arinel (Duke University, United States)
"Mapping the Gut-Brain Neural Circuitry in Larval Zebrafish"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Interpreting Neural Manipulations
Discussion Leader: Dmitry Rinberg (Neuroscience Institute, New York University , United States)
6:00 pm - 6:20 pm
Bing Brunton (University of Washington, United States)
"Quantity Has a Quality All its Own: On Developing Quantitative Predictive Models of Perturbations with Feedback"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
Jim Heys (University of Utah, United States)
"Attractor Dynamics and Neural Sequences: Understanding the Mechanisms of Flexible Temporal Memory"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Daniel O'Shea (Stanford University, United States)
"Direct Neural Perturbations Reveal a Dynamical Mechanism for Robust Computation"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Amit Vinograd (California Institute of Technology, United States)
"Causal Evidence of a Line Attractor Encoding an Affective State"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Gabe Loewinger (National Institute of Mental Health, United States)
"Causal Inference for Optogenetics Behavioral Experiments"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Neural Circuits for Complex Behavior
Discussion Leader: Moriel Zelikowsky (University of Utah, United States)
9:00 am - 9:20 am
Robert Froemke (New York University Grossman School of Medicine, United States)
"Love, Death, and Oxytocin: The Challenges of Mouse Maternity"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Valery Grinevich (Central Institute of Mental Health, Heidelberg University, Germany)
"Distinctiveness of Neuroendocrine Cells Revealed by Optogenetics: Oxytocin Neuron as an Example"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Francesco Papaleo (Istituto Italiano di Tecnologia, Italy)
"Interbrain Circuits of Emotion Recognition"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Camilla Bellone (University of Geneva, Switzerland)
"Dissecting the Role of Ventral Striatum in Social Threat Avoidance"
11:05 am - 11:15 am
Discussion
11:15 am - 11:35 am
Tatiana Korotkova (University of Cologne, Germany)
"State-Dependent Regulation of Nutritional and Social Needs by Inputs from Prefrontal Cortex to the Lateral Hypothalamus"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Hugo Tejeda (National Institute of Mental Health, United States)
"Prefrontal Cortical Neuropeptidergic Control of Threat Processing"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Oded Klavir (University of Haifa, Israel)
"Neural Circuits of Fear Memory-Driven Actions"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Precision Optogenetics
Discussion Leader: Ian Oldenburg (Rutgers University, United States)
6:00 pm - 6:20 pm
Rosa Cossart (INMED, INSERM u1249, France)
"Shedding Light on the Functional Wiring of the Hippocampus"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
Mark Histed (National Institute of Mental Health, National Institutes of Health, United States)
"Recurrent Networks of the Cerebral Cortex: Patterned Inputs, Computations, and Sequences"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Dmitry Rinberg (Neuroscience Institute, New York University , United States)
"Probing Perception with Optogenetics"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Amy Monasterio (Boston University, United States)
"Engram Cell Dynamics Before and After Learning"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Harshida Pancholi (University of Texas Southwestern Medical Center, United States)
"Singing in the Brain: A Window Into Motor Control Using in vivo Holography"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Circuit Dynamics Transforming Moments to Engrams
Discussion Leader: Yaniv Ziv (Weizmann Institute of Science, Israel)
9:00 am - 9:20 am
Gisella Vetere (ESPCI, Paris, France)
"Memory Engram Dissection Reveals Distinct Ensembles Recruited at Encoding"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Laura DeNardo (University of California, Los Angeles, United States)
"Temporal Evolution of Cortical Ensembles Promoting Remote Memory Retrieval"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Inbal Goshen (Hebrew University of Jerusalem, Israel)
"Astrocytes in High Brain Function"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Kazumasa Tanaka (Okinawa Institute of Science and Technology University, Japan)
"Heterogeneous Representations in the Hippocampus"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Anna Gillespie (University of Washington, United States)
"A Neurofeedback Approach to Manipulating Hippocampal Replay"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Tomás Ryan (Trinity College Dublin, Ireland)
"Cold Sensitive Engrams Control Whole-Body Thermoregulatory Responses"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Megha Sehgal (The Ohio State University, United States)
"Role of Neuronal and Dendritic Plasticity within Retrosplenial Cortex in Memory Organization"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Clinical Applications of Optogenetics
Discussion Leader: Camilla Bellone (University of Geneva, Switzerland)
6:00 pm - 6:40 pm
Botond Roska (Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland)
"Restoring Vision Using Optogenetics"
6:40 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Karine Fenelon (University of Massachusetts, Amherst, United States)
"Deciphering Brainstem Synaptic Mechanisms Underlying Prepulse Inhibition of Startle Relevant to Schizophrenia"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
Tobias Moser (University Medical Center Göttingen, Germany)
"Toward Optogenetic Hearing Restoration"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure