Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Channels and Transporters in Chloroplasts
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:05 pm
"Metabolite Fluxes Between Cytosol and Chloroplast"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Role of the Magnesium Transporter MGT10 in Chloroplast Development and Photosynthesis"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Metabolite Transport in Photosynthesis"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Isolation of Acidocalcisomes from Dunaliella bardawil "
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Channels and Transporters in Mitochondria
9:00 am - 9:20 am
"Structure and Function of Mitochondrial Complexes: The Molecular Mechanism of Complex I"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Spatiotemporal Dynamics of OXPHOS Complexes in Live Cells"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"NAD+ Transport into Mitochondria"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Mitochondrial Carboxylate Transporters and Regulation of Macronutrient Metabolism"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Mitochondrial Import of S-Adenosyl Methionine and the Mitochondrial Methylproteome"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Molecular Identity and Regulatory Mechanisms of the Mitochondrial Uncoupling Protein of Regular Somatic Tissues"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Unique Functional Properties of Mitochondria Bound to Lipid Droplets"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Ion Homeostasis Established by Organelle Transporters
7:30 pm - 7:50 pm
"Physiological Roles of Endo-Lysosomal Chloride/Proton Exchangers"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Organellar Transporters Controlling Iron and Manganese Homeostasis in Plants"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Ion Homeostasis in Rice"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Roles of Vacuolar NHX-Type Transporters in Plant Growth and Development"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Channels and Transporters in Vacuoles and Endo-Lysosomes
9:00 am - 9:20 am
"Structure and Regulation of the Yeast Vacuolar H+ -ATPase"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Control of Phosphate Homeostasis by Acidocalcisome-Like Vacuoles"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"A New Pathway for Degrading Lysosomal Transporters"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Agonist-Selective Permeability in an Intracellular Ion Channel"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Down-Regulation of Lysosome Membrane Transporters in Yeast"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"PQLC2 Signals Lysosomal Cationic Amino Acid Abundance to the C9orf72 Complex"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Organellar DNA Reporters for Discovery Biology"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Organelle Membrane Transport in Calcium Signaling
7:30 pm - 7:50 pm
"Cryo-EM Study of the Mitochondrial Calcium Uniporter"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"X-Ray and Cryo-EM Study of the Mitochondrial Calcium Uniporter"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Unique Mode of Regulation of the Mitochondrial Na+ /Ca2+ Exchanger NCLX"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Calcium and Long-Distance Signaling in Plants"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Transferring Lipids Across and Between Organelle Membranes
9:00 am - 9:20 am
"VPS13 and Chorein_N Motif Proteins Function in Lipid Transfer"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Lipid Transporting ABC Transporters in Plant"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Structural Investigation of SSD Proteins in Sterol Sensing and Transport"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Transduction of the Hedgehog Signal from Patched to Smoothened"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Structural Basis for Sterol Transporter-Like Activity of the Hedgehog Receptor PTCH1"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Remote Control of Inter-Organellar Membrane Contact Sites Using Optogenetic Tools"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Structural Insights and Autoregulation of a P4-ATPase Lipid Flippase"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Channels and Transporters in the Nucleus and Secretory Pathway
7:30 pm - 7:50 pm
"Molecular Insights into the Regulation of the TRP Channel Polycystin-2"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A Calcium/cAMP Signaling Loop at the ORAI1 Mouth Drives Channel Inactivation to Shape NFAT Induction"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Comparison of the Vacuolar and Golgi V-ATPases from Saccharomyces cerevisiae "
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Vesicular Nucleotide Transporter (VNUT) as a Target for Drug Discovery"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Different Modes of Ionic Coupling by a Family of Organic Anion Transporters"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Organellar Transport Proteins in Human Diseases
9:00 am - 9:20 am
"The Role of Primary Cilium Ion Channels in Cancer"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Why Succinate? A Model for Systemic Bioenergetic Signaling"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"The Mitochondrial Protein VDAC1 as a Target for Cancer, Neurodegenerative, Diabetes and Autoimmune Diseases"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Pathophysiology of Endolysosomal Disorders in the Kidney"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"SK Channel Activation Prevents Ferroptosis by Metabolic Reprogramming"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Endosomal pH Regulator Sodium Hydrogen Exchanger Isoform 9 Maintains Glioblastoma Stem Cells by Stabilizing Multiple Receptor Tyrosine Kinases"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Protons to Patients: Insights into ClC-7 Function from a Novel Disease Mutation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Organelle Integration of Metabolism and Signaling
7:30 pm - 7:50 pm
"Dynamic Organization of Intracellular Organelle Networks"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Integration of Retrograde, ROS and ABA Signalling Across Evolutionary Scales"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Crosstalk Between Lysosomes and Mitochondria in mTOR Signaling"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Metabolic Control of Sleep"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure