| SATURDAY |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Common biological pathways in oxidative stress and disease |
| Discussion Leaders: Tomas Prolla (University of Wisconsin Madison, USA) and Donald A. McCarthy (Albany Medical College, USA) |
| 3:45 pm - 4:00 pm | Christine Vogel (New York University, USA)
"Global and specific proteome changes in response to oxidative stress" |
| 4:00 pm - 4:05 pm | Discussion |
| 4:05 pm - 4:20 pm | Eric L. Bell (Department of Biology, MIT, Cambridge, USA)
"SirT3 negatively regulates hypoxia inducible factor 1 alpha through mitochondrial ROS production" |
| 4:20 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Oxidative stress, protein and organelle dysfunction, and disease |
| Discussion Leaders: Julie K. Andersen (Buck Institute for Research on Aging, USA) and Elizabeth Alli (Stanford University, USA) |
| 7:30 pm - 7:45 pm | Joungil Choi (University of Maryland, Baltimore, USA)
"Mitochondrial dysfunction linking metabolic alteration and neurodegeneration" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Martin Jastroch (Buck Institute for Research on Aging, USA)
"Physiological significance of mitochondrial uncoupling protein 1 in the control of reactive oxygen species and oxidative capacity" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Sulay Rivera-Sanchez (University of Puerto Rico, USA)
"Increases in mitochondrial DNA damage and silencing of APE1 are associated with mitochondrial collapse in Huntington's disease" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Qaisar Ali (College of Pharmacy, Houston, USA)
"Role of angiotensin II AT2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker rats" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Kathryn Page (Buck Institute for Research on Aging, USA)
"Aluminium toxicity, metallostasis and aging" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Suzanne Angeli (Buck Institute for Research on Aging, USA)
"Manganese toxicity in Caenorhabditis elegans: implications for Parkinson's disease" |
| 9:25 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Cutting edge technologies for studying oxidative stress and disease |
| Discussion Leader: Victoria Lunyak (Buck Institute for Research on Aging, USA) and Dario C. Ramirez (University of Oklahoma, USA) |
| 9:00 am - 9:18 am | Yuval Aluf (Technion, Israel)
"Novel multifunctional marker molecule detects dopamine-derived oxidative stress in a pre-clinical Parkinson's disease model" |
| 9:18 am - 9:24 am | Discussion |
| 9:24 am - 9:42 am | Anthony M Franchini (Albany Medical College, USA)
"FcR-targeting of Francisella tularensis antioxidant mutants enhance innate and adaptive immune responses against bacterial infection" |
| 9:42 am - 9:48 am | Discussion |
| 9:48 am - 10:06 am | Christos Gabrielides (Newcastle University, UK)
"Superoxide dismutase 2 downregulation and mitochondrial respiration in osteoarthritis" |
| 10:06 am - 10:12 am | Discussion |
| 10:12 am - 10:30 am | Marcela Maldonado (University of Minnesota, USA)
"Abberent regulation of NFKB pathway in immunoproteasome-deficient retinal pigment epithelial cells" |
| 10:30 am - 10:36 am | Discussion |
| 10:36 am - 10:54 am | Laura L Stone (University of Minnesota, USA)
"Identification of serum metabolite biomarkers in rats present at early stages of ischemic stroke using 1H-NMR Spectroscopy" |
| 10:54 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Career Orientation Session |
|
Catherine Kunst (Innovation park, Tallahasse, Florida, USA), Asma Zaidi (Kansas City University of Medicine and Biosciences, USA), and Bita Nakhai (Office of Scientific Review, NIH, USA) will cover the following topics:
- Opportunities and challenges in academic versus industrial research
- Successful research fundraising
- Principles in lab mentorship
- Successful networking
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
