| SUNDAY |
| 2:00 pm - 6:00 pm | Arrival, Gordon Conference Registration, Hotel check-in |
| 6:00 pm - 7:00 pm | Dinner |
| 7:30 - 9:30 pm | Novel Antioxidant Actions |
| Chair: Roland Stocker, Heart Research Institute, Sydney, Australia |
| 7:00 pm - 7:40 pm | Dorothy Morre, Ph.D.,Purdue University, West Lafayette, IN
Cell Surface NADH Oxidases and Their Interactions with Dietary Antioxidants |
| 7:40 pm - 8:10 pm | Anil K. Jaiswal, Ph.D., Baylor College of Medicine, Houston, TX
Antioxidant Regulation of Genes Encoding Enzymes that Detoxify Xenobiotics and Carcinogens |
| 8:10 pm - 8:50 pm | Susan Doctrow, Ph.D., Eukarion, Inc., Bedford, MA
Synthetic Superoxide Dismutase/Catalase Mimetics with Protective Activity in Models for Neurodegeneration and Aging |
| 8:50 pm - 9:30 pm | Noriko Noguchi, Ph.D.,University of Tokyo, Tokyo, Japan
Regulation of gene expression of proteasome subunits by antiatherogenic antioxidants |
| MONDAY |
| 9:00 am - 12:30 pm | Mitochondrial Function in Health and Disease |
| Chair: Matthew Grisham, Ph.D., LSU Health Sciences Center, Shreveport, LA |
| 7:30 pm - 8:15 pm | Michael P Murphy, Ph.D., Dunn Nutrition Unit, Cambridge, UK
Mitochondrially Targeted Antioxidants |
| 8:15 pm - 9:00 pm | Doug Green, Ph.D.,La Jolla Institute for Allergy, San Diego, CA
Cytochrome c Release and Apoptosis |
| 10:30 am - 10:45 am | Coffee Break |
| 10:45 am - 12:15 am | Reactive Oxidants and Cancer |
| Chair: Ann E. Aust, Ph.D., Utah State University, Logan, UT |
| 10:45 am - 11:30 am | Curtis C. Harris, M.D., NIH, Bethesda, MD
Increased p53 Mutation Load in Nontumorous Human Liver of Wilson Disease and Hemochromatosis |
| 11:30 am - 12:15 am | Tom Hei, Ph.D., Columbia University, NY
Oxidative Damage and Environmental Carcinogens |
| 12:15 pm - 12:30 pm | Conference Photograph |
| 12:30 pm - 1:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm - 7:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Oxidative DNA Damage and Repair |
| Chair: Sigmund Weitzman, M.D., Northwestern University Medical School, Chicago, IL |
| 9:00 am - 9:45 am | Cynthia Burrows, Ph.D., University of Utah, Salt Lake City, UT
The One Electron Chemistry of 8-oxo-Guanine |
| 9:45 am - 10:30 am | David M. Wilson III, Ph.D., Lawrence Livermore National Laboratory, Livermore, CA
Repair of Oxidative DNA damage: from genetic variation, through biochemistry, to predicting disease susceptibility |
| 9:00 am - 9:45 am | Prabhat Goswami, Ph.D., University of Iowa, Iowa City, IA
Redox signaling early in the cell cycle activates G1-regulatory proteins |
| TUESDAY |
| 9:00 am - 12:30 pm | Antioxidant and Signaling Functions of Thiol Enzymes |
| Chair: Henry Jay Forman, Ph.D., University of Alabama at Birmingham, Birmingham, AL |
| 9:00 am - 9:45 am | Al Claiborne, Ph.D.,Wake Forest University Medical Center, Winston-Salem, NC
Cysteine Oxidation, Sulfenic Acids and Thiol Regulation |
| 9:45 am - 10:30 am | Sang Won Kang, Ph.D.,NHLBI, NIH, Bethesda, MD
Intracellular Messenger Function of Hydrogen Peroxide |
| 10:30 am - 10:45 am | Coffee Break |
| 10:45 am - 11:30 am | Arne Holmgren, Ph.D., Karolinska Institute, Stockholm, Sweden
Physiological Functions of Thioredoxin and Thioredoxin Reductase |
| 11:30 am - 12:15 pm | Aron Fisher, M.D., University of Pennsylvania Medical Center, Philadelphia, PA
1-Cys Peroxiredoxin, a Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities |
| 11:30 am - 12:15 pm | Bita Sahaf, Ph.D., Stanford University, Stanford, CA
Differences in Surface Thiols and intracellular Thioredoxin among lymphocyte subtypes predict the importance of redox regulation for their function |
| 12:30 pm - 1:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm - 7:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Thiol Regulation of Protein Function |
| Chair: Christine Winterbourn, Ph.D., University of Otago, New Zealand |
| 7:30 pm - 8:15 pm | Garth Powis, Ph.D.,University of Arizona, Tucson, AZ
The Role of Thioredoxin in Cell Growth and Cancer |
| 8:15 pm - 9:00 pm | Carl White, M.D.,University of Colorado Health Sciences Center, Denver, CO
Hypoxic preconditioning protects lung cells against oxidative stress: roles of phosphatidyl inositol 3-kinase and hexokinase |
| 7:30 pm - 8:15 pm | Hajimi Nakamura, Kyoto University, Kyoto, Japan
Extracellular thioredoxin in infection and inflammation |
| WEDNESDAY |
| 9:00 am - 12:30 pm | Protein Oxidation and Disease |
| Chair: Anthony J. Kettle, Ph.D., University of Otago, New Zealand |
| 9:00 am - 9:45 am | Christian Schoneich, Ph.D.,University of Kansas, Lawrence, KS
Oxidative Inactivation of CaATPase and Characterization of Sulfur Oxidation Sites in Proteins |
| 9:45 am - 10:30 am | Michael Davies, Ph.D.,Heart Research Institute, Sydney Australia
Protein Peroxides and Their Pathophysiological Significance |
| 10:30 am - 10:45 am | Coffee Break |
| 10:45 am - 11:30 am | Stan Hazen, M.D., Ph.D.,Cleveland Clinic Foundation, Cleveland, OH
Peroxidases and the Pathogenesis of Inflammatory Diseases |
| 11:30 am - 12:15 pm | Albert van der Vliet, University of California, Davis, CA
Oxidants, Nitrosants, and the Lung |
| 11:30 am - 12:15 pm | John F. Keaney, Jr., M.D., Boston University School of Medicine, Boston, MA
Oxidative stress-induced p53 phosphorylation in endothelial cells involves PDGF receptor-mediated ATM kinase activation |
| 12:30 pm - 1:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm - 7:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Reactive Nitrogen Species |
| Chair: Victor Darley-Usmar, Ph.D.,University of Alabama at Birmingham, Birmingham, AL |
| 7:30 pm - 8:15 pm | Cecilia Giulivi, Ph.D.,University of Minnesota, Duluth MN
Mitochondria and Nitric Oxide Synthases |
| 8:15 pm - 9:00 pm | Joseph Beckman, Ph.D., Linus Pauling Institute, Oregon State University, Corvalis, OR
Role of nitrative stress in neurodegeneration |
| 8:15 pm - 9:00 pm | Diana Wertz, Ph.D., University of California, Berkeley, CA
Investigating the biological role of plasma membrane bound copper amine oxidase |
| THURSDAY |
| 9:00 am - 12:30 pm | Microbial Killing and Survival |
| Chair: Harry Ischiropoulos, Ph.D., Children's Hospital of Philadelphia, Philadelphia, PA |
| 9:00 am - 9:45 a.m | James Imlay, Ph.D., University of Illinois, Urbana, IL
Iron and Bacterial Responses to Oxidative Stress |
| 9:45 am - 10:30 am | Rafael Radi, Ph.D., Universidad de la Republica, Montevideo, Uruguay
Nitric oxide and peroxynitrite in Trypanosoma cruzi survival and death |
| 10:30 am - 10:45 am | Coffee Break |
| 10:45 am - 11:30 am | Carl Nathan, M.D.,Weill Medical College of Cornell University, New York, NY
New aspects of antioxidant defense in mycobacterium tuberculosis |
| 11:30 am - 12:15 am | Ferric Fang, Ph.D., University of Colorado Health Sciences Center, Denver, CO
Antimicrobial activities of NADPH Oxidase and Inducible Nitric Oxide Synthase |
| 11:30 am - 12:15 am | Stephen Christen, Ph.D., University of Berne, Berne, Switzerland
The role of reactive oxygen species in bacterial meningitis: possible mechanisms of brain damage |
| 12:30 pm - 1:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm - 7:00 pm | Conference Banquet |
| Keynote Lecture |
| Chairs: Ann E. Aust, Ph.D., Utah State University, Logan, UT
Christine Winterbourn, Ph.D., University of Otago, New Zealand |
| 7:30 pm - | Larry Marnett, Ph.D., Vanderbilt University, Nashville, TN
Sex, Drugs, and Cyclooxygenase |
| FRIDAY |
| Depart |
