| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | CHEMISTRY OF REDOX SIGNALING |
| Chair: Garry Buettner (University of Iowa) |
| 7:30 pm - 8:05 pm | Jon Fukuto (UCLA)
Reactive nitrogen species in signal transduction |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:50 pm | Aron B. Fisher (University of Pennsylvania)
Peroxiredoxin VI,a dual function enzyme with glutathione peroxidase and phospholipase A2 activities |
| 9:50 pm - 9:00 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | IRON HOMEOSTASIS AND NITRIC OXIDE METABOLISM & EMERGING TECHNOLOGIES AND BIOMARKERS IN FREE RADICAL BIOLOGY |
| Chair: Balaraman Kalyanaraman (Medical College of Wisconsin) |
| 9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
| 9:05 am - 9:35 am | Jean Claude Drapier (Centre National de la Recherche Scientifique, Gif-sur-Yvette, France)
Nitric oxide and peroxynitrite in the modulation of iron regulatory proteins |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:00 am | David M. Krzywanski (University of Alabama at Birmingham)
Nitrogen dioxide induced protein nitration does not correlate with acute cell injury |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:30 am | Coffee Break |
| 10:30 am - 11:05 am | Ronald Mason (National Institutes of Health, USA)
Capturing Protein and DNA radicals in Time and Space by Immuno-spin trapping |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am | Group Photo |
| 11:30 am - 12:00 pm | Ohara Augusto (Instituto de Química-Universidade de São Paulo, Brazil)
Carbonate radical: detection, biomarkers and bioactivities |
| 12:00 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Silvina Bartesaghi (Universidad de la República, Montevideo, Uruguay)
Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe N-t-BOC L-tyrosine tert butyl ester (BTBE) |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | NADPH OXIDASES IN SIGNALING |
| Chair: John Eaton (University of Louisville) |
| 7:30 pm - 8:05 pm | David Lambeth (Emory University)
The NOX family of proteins |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:50 pm | Tom Leto (National Institutes of Health, USA)
Regulation and composition of non-phagocyte oxidases |
| 8:50 pm - 9:00 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | OXIDANTS-ANTIOXIDANTS IN INFECTION AND INFLAMMATION |
| Chair: Etsuo Niki (Human Stress Signal Research Center, Midorigaoka, Ikeda, Japan) |
| 9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
| 9:04 am - 9:40 am | Madia Trujillo (Universidad de la República, Montevideo, Uruguay)
Trypanothione and peroxiredoxins during mammalian cell infection by trypanosomatids |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Horacio Botti (Universidad de la República, Montevideo, Uruguay)
Studies on the Formation of Redox Variants of Human Serum Albumin: Focusing on Sulfur Oxidation and Sulfinate Formation at C34 by Electrophiles and Free Radicals |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:35 am | Coffee Break |
| 10:35 am - 11:10 am | Mary Sorci Thomas (Wake Forrest)
Role of HDL ApoA-I in inflammation and cholesterol homeostasis |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:55 am | Stefan Ryter (University of Pittsburgh)
Carbon monoxide suppresses inflammation |
| 11:55 am - 12:05 pm | Discussion |
| 12:05 pm - 12:25 pm | Alireza Mani (University College London)
The metabolism of chlorotyrosine, and identification |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | LIPID DERIVED RADICALS AND NITRIC OXIDE |
| Chair: Bruce Freeman (University of Pittsburgh) |
| 7:30 pm - 8:05 pm | Homero Rubbo (Universidad de la República, Montevideo, Uruguay)
Biological activity of nitrolipids and nitric oxide derivatives of vitamin E |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:50 pm | Paul Baker (UAB)
Mass spectrometric detection and characterization of nitrolipids |
| 8:50 pm - 9:00 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THIOL OXIDATION IN SIGNALING |
| Chair: Robert Floyd (Oklahoma Medical Research Foundation) |
| 9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
| 9:05 am - 9:40 am | Matilde Maiorino (University of Padova, Italy)
Non-antioxidant functions of glutathione peroxidases |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Alessandra Rinna (University of California, Merced)
Stimulation of the alveolar macrophage respiratory burst by ADP causes selective glutathionylation of protein tyrosine phosphatase 1B |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:35 am | Coffee Break |
| 10:35 am - 11:10 am | Tak Yee Aw (Louisiana State University)
The redox state regulates signaling |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:55 am | P. Boon Chock (National Institutes of Health, USA)
The physiological function of glutathionylated actin |
| 11:55 am - 12:05 pm | Discussion |
| 12:05 pm - 12:25 pm | Fernando Antunes (Instituto de Investigação Científica Bento da Rocha Cabral, Lisboa, Portugal)
Regulation of plasma membrane permeability to H2O2 during adaptation to H2O2 |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:00 pm | SOURCES OF REACTIVE SPECIES |
| Chair: Kelvin Davies (University of Southern California) |
| 7:30 pm - 8:05 pm | Edgar Pick (Sackler School of Medicine, Tel Aviv University, Israel)
Regulation of the phagocyte NADPH oxidase by cytosolic components - From membrane recruitment to "meeting Mr. Right" |
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:50 pm | Paul Brookes (University of Rochester)
Mitochondria, S-nitrosothiols and cardiac ischemia |
| 8:50 pm - 9:00 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:40 am | REDOX AND ELECTROPHILIC SIGNALING |
| Chair: Lester Packer (University of Southern California) |
| 9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
| 9:05 am - 9:40 am | Akira Kobayashi (University of Tsukuba, Japan)
Nrf2-Keap pathways |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Douglas Thomas (National Institutes of Health, USA)
Superoxide fluxes control NO-induced post-translational regulation of sGC, p53, and HIF-1a |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am - 10:35 am | Coffee Break |
| 10:35 am - 11:10 am | Michel Toledano (Service de Biologie Moléculaire Systémique, Gif-sur-Yvette, France)
Signaling for regulation of transcription factors |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:50 am | Aimee Landar (UAB)
The electrophile responsive proteome: characterization and functional significance |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:30 pm | Panel Discussion |
| What Have We Learned In Twenty Five Years Of Oxygen Radical Gordon Conferences And What Do We Still Need To Learn? |
| Discussion Leader: Henry Jay Forman |
| Panel Members: Kelvin Davies, Bruce Freeman, Balaraman Kalyanaraman, John Eaton, Etsuo Niki, Robert Floyd, Garry Buettner, Norman Krinsky, Lester Packer |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Conference Banquet |
| 8:00 pm - 9:00 pm | CONFERENCE KEYNOTE LECTURE |
| Chair: Norman Krinsky |
| 8:00 pm - 8:50 pm | Christine Winterbourn (New Zealand)
Understanding oxidative stress: From the chemistry of superoxide to the lungs of babies |
| 8:50 pm - 9:00 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
