SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | New Signaling Paradigms in Redox Biology |
| Discussion Leader: Victor Darley-Usmar |
7:40 pm - 8:10 pm | Bruce Freeman (University of Pittsburgh)
"Redox-derived anti-inflammatory signaling mediators" |
8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:00 pm | Michael Marletta (University of California, Berkeley)
"Building Receptors for Selective Responses to NO and O2: Nature's Way" |
9:00 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
9:30 pm - 11:30 pm | Reception |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Oxygen Radicals in Cardiovascular Disease |
| Discussion Leaders: Francisco Schopfer and Mark Gladwin |
9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
9:05 am - 9:25 am | John Keaney (University of Massachusetts Medical School)
"Redox control of vascular homeostasis" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | David Gutterman (Medical College Wisconsin)
"Role of Reactive Oxygen Species in Physiological Regulation of the Human Coronary Microcirculation" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Richard Cohen (Boston University)
"Oxidative post-translational protein modifications in cardiovascular pathophysiology" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Discussion |
11:05 am - 11:25 am | Stan Hazen (Cleveland Clinic)
"ApoA1 Oxidation and formation of dysfunctional HDL: Structural, functional and clinical studies" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Tom McIntyre (Cleveland Clinic)
"Oxidatively Truncated Phospholipids Connect TNFa to Apoptosis" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:20 pm | Emilia Kansanan (University of Eastern Finland) |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Probes for Detection of ROS |
| Discussion Leaders: Ginger Milne and Richard Cohen |
7:30 pm - 7:50 pm | Christopher Chang (Howard Hughes Medical Institute, Berkeley)
"Molecular imaging approaches to studying peroxide biology in living cells and animals" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Balaraman Kalyanaraman (Medical College Wisconsin)
"Real-time monitoring of ROS/RNS in cells: a dream or reality?" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Tobias Dick (German Cancer Research Center, Heidelberg)
"Novel pathways of regulatory protein thiol oxidation" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Maolin Guo (University of Massachusetts) |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
9:30 pm - 11:30 pm | Reception |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mass Spectrometry Applications in Oxygen Radical Research |
| Discussion Leaders: Tom McIntyre and Stan Hazen |
9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
9:05 am - 9:25 am | Ginger Milne (Vanderbilt University)
"Quantification of Urinary Eicosanoid Metabolites: Technical Considerations and Clinical Utility" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Robert Murphy (University of Colorado, Denver)
"Diversity and Implication of Oxidized Cholesterol Ester Molecular Species in Human Atherosclerotic Plaques" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Francisco Schopfer (University of Pittsburgh)
"Formation and signaling of omega-3 fatty acid-derived electrophiles in inflammation" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:25 am | Harry Ischiropoulos (University of Pennsylvania)
"Structural and functional diversity of protein S-nitrosocysteine residues" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Ian Blair (University of Pennsylvania)
"Mitochondrial oxidative stress" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:20 pm | Molly Sheehan (University of Pennsylvania School of Medicine) |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mitochondria: A redox organelle |
| Discussion Leaders: Rakesh Patel and Ana Denicola |
7:30 pm - 7:50 pm | Irfan Rahman (University of Rochester)
"Oxidative stress and epigenetic events in inflammation and pulmonary diseases" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Navdeep Chandel (Northwestern University)
"Mitochondrial ROS regulate signaling"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Anne Diers (Medical College of Wisconsin) |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:10 pm | Jianhua Zhang (University of Alabama) |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
9:30 pm - 11:30 pm | Reception |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Heme Proteins and Reactive Nitrogen Species |
| Discussion Leaders: Tony Kettle and Eddie Weitzberg |
9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
9:05 am - 9:25 am | Eddie Weitzberg (Karolinska Institute, Sweden)
"Dietary nitrate: Nutritional, therapeutic and physiological implications" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Rakesh Patel (University of Alabama at Birmingham)
"Modulation of vascular inflammation by the red blood cell" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:15 am | Willem Koppenol (Swiss Federal Institute of Technology) |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:15 am | Mark Gladwin (University of Pittsburgh)
"Functional properties of neuroglobin as a allosteric-redox regulated nitrite reductase" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Olivier Boutaud (Vanderbilt University)
"Acetaminophen and hemoprotein redox cycling: new tricks for an old drug" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:05 pm | Michael Davis (Heart Research Institute, Sydney) |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Chang Chen (Chinese Academy of Science, Beijing) |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Cancer |
| Discussion Leaders: Ian Blair and Navdeep Chandel |
7:30 pm - 7:50 pm | Greg Thatcher (University of Illinois)
"Targeting quinone-derived ROS to the nucleus: conflicting roles in estrogen carcinogenesis and in cancer therapy" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Daret St. Clair (University of Kentucky)
"Oxidative Stress Mediated Retrograde Signaling" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | J. Andres Melendez (Universtiy of Albany)
"Redox-signaling and control of cellular senescence" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Albert Girotti (Medical College of Wisconsin) |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | General Discussion |
9:30 pm - 11:30 pm | Reception |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Oxidative Stress and Disease |
| Discussion Leaders: Bruce Freeman and Andres Melendez |
9:00 am - 9:05 am | Announcements and Chair's Introductory Remarks |
9:05 am - 9:25 am | Ana Denicola (University of the Republic, Montevideo)
"On the reactivity of peroxiredoxin with peroxides" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Yvonne Jannsen-Heininger (University of Vermont)
"Glutaredoxin controlled cysteine oxidation of the death receptor Fas: Role in tissue fibrosis" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:15 | Ohara Augusto (University of Sao Paulo) |
10:15 am - 10:25 am | Discussion |
10:25 am - 10:55 am | Coffee Break |
10:55 am - 11:15 am | Tony Kettle (University of Otago, New Zealand)
"The Superiority of Superoxide as a Reactive Oxygen Species" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Erin Heckler (University of Medicine and Dentistry of New Jersey) |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:00 pm | William Willmore (Carleton University |
12:00 pm - 12:05 pm | Discussion |
12:05 pm - 12:20 pm | Hang Zhao (NHLBI ) |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session II |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session |
| Discussion Leaders: Valerie O'Donnell and Neil Hogg |
7:30 pm - 8:00 pm | Closing Remarks and Keynote Speaker Introduction |
8:00 pm - 8:45 pm | Keynote Lecture: Victor Darley-Usmar (University of Alabama at Birmingham)
"Putting the Bio into Energetics; The Emerging Role of Mitochondria in Health and Disease" |
8:45 pm - 9:15 pm | Discussion |
9:30 pm - 11:30 pm | Reception |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |