Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: The Tumor Myeloid Microenvironment
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:10 pm
Introduction by Discussion Leader
8:10 pm - 9:10 pm
"Monocytes, Dendritic Cells, and Macrophages – A Migratory Journey"
9:10 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Innate Immunity from a Cancer Perspective
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Tumor-Associated Myeloid Cells: The Good, the Bad, and the Ugly"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Primary Tumor Associated Macrophages Activate Programs of Invasion and Dormancy in Disseminating Tumor Cells"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Post-infectious Microglia: Harnessing Phagocytosis to Protect the Brain"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
" Neutrophils and PMN-MDSC: Two-Faced Janus of Innate Immunity"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Regulation of Neutrophil Recruitment to the Tumor Niche in Breast Cancer"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address challenges women face in science and issues of diversity and inclusion. The program supports the professional growth of all members of our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Outside Influences on Phagocyte Function
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Listeriolysin O Induces Phagosome Stress Response"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"A New Challenge at the Oral Mucosa: Neutrophils Coping with Emerging Oral Pathogens"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Some Wine with Your Meal? PIKfyve Drives Macropinosome/Phagosome Fusion to Aid Digestion"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Elucidating Key Interactions Between Coccidioides and Macrophages"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
The Cytoskeleton and Membrane Trafficking
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Actin and Myosin Cross-Talk During Phagocytosis"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Enhancing Macrophage Phagocytosis of Cancer Cells Targeted with Therapeutic Antibodies"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"How to Build an Efficient Phagosome: Lessons from Pathogens"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"4D Imaging Reveals New Insight into Macropinosome Formation and Closure"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Phagocytes Prevent Invasive Growth of Aspergillus Hyphae in Zebrafish Larvae"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Emerging Phagocyte Influencers
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Neutrophils Cooperate in the Biosynthesis of Lipid Mediators Driving Swarming"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Fate and Functions of Macrophages in the Heart"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Resolvin E4 is activated in Physiologic Hypoxia: Biosynthesis and Actions of the Newest Resolvin"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Role for TL1A in Innate Intestinal Inflammation and Colitis Associated Cancer"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Multisystem Profiling Reveals Phagocyte Responses in Divergent Outcomes to Viral Infection"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Macrophage Reprogramming in Tuberculosis"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Neutrophil Signaling in Autoimmune and Inflammatory Disease Models"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Metabolic Reprogramming of Neutrophils by Francisella tularensis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"How Phagocytes Acquired the Capability of Hunting and Removing Pathogens from a Human Body: Lessons Learned from Chemotaxis and Phagocytosis of Dictyostelium discoideum"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Phagocyte-Pathogen Cross-Talk
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Use of Zebrafish to Study Shigella-Phagocyte Interactions"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Playing with Fire: Neutrophils in the Pathogenesis of Neisseria Gonorrhoeae Infection"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"The Expression of Integrin aDß2 (CD11d/CD18) on Neutrophils Promotes Macrophage Migration and Prevents the Development of Endotoxemia and Sepsis"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Training Innate Immunity in Zebrafish Using Shigella"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Inflammasomes and Autophagy
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"IVIg Targets IL-1ß-Expressing Neutrophils in Kawasaki Disease and MIS-C"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Phagosome Resolution Maintains the Degradative Capacity in Phagocytes"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"The Underappreciated Role of Neutrophils as a Source of IL-1a and IL-1ß in Microbial Infections"
11:15 am - 11:25 am
Discussion
11:25 am - 11:50 am
"The Neutrophil in Autoinflammation"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Neurorepellent SLIT2 Promotes Host Innate Immune Responses during Bacterial Infection"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Transporters and Environmental Effects on Phagocyte Responses
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Solute Carrier Transporters Modulate Inflammasome Activity by Regulating Autophagy in Dendritic Cells"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Solute Fluxes and the Surveillance of Fluid by Resident Macrophages"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Characterization of Lipid ROS-Mediated Biological Events Coupled with NADPH Oxidases during Ferroptosis in Macrophages"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Nexinhib20 Inhibits Neutrophil Adhesion and ß2 Integrin Activation by Antagonizing Rac-1-GTP Interaction"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure