Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Cell Signaling in Phagocytes
3:45 pm - 3:55 pm
"Optogenetic Control Over Phagocytosis Reveals Molecular Memory of Prior Fc Receptor Activation"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"STAT1 is Essential for the Expansion of Hepatic Monocyte & Macrophage Populations in Macrophage Activation Syndrome"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Extended Lifespan and Atypical Death of Helicobacter pylori -Infected Human Neutrophils"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Host-Pathogen Interactions in Disease
7:30 pm - 7:40 pm
"Determining the Cellular and Molecular Mechanisms by which Biobran (MGN-3) Mediates Innate Immunity in a Hyperglycaemic Model of a Diabetic Foot Ulcer Infection."
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Deletion of Nrf2 During Influenza-Staphylococcus aureus Super-Infection Leads to Increased Bacterial Burden"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Characterization of B. pertussis Autophagic Response in a Model of Alveolar Macrophages"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Recombinant Virulence-Associated Protein A Restores Replication of Avirulent Rhodococcus equi in Macrophages Independently of Surface Receptors TLR2, CR3, and Fc?RIII"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"LC3-Associated Phagocytosis in Airway Epithelial Cells Protects Against Influenza A Virus-Induced Lethal Infection"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Increased Neutrophil Oxidative Stress, TNFR and RAGE Contribute to the Hyperinflammatory Immunopathology of Diabetes-Tuberculosis: Data from a Cellular Model and Human Cohort"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Yersinia pestis Actively Influences Extracellular Vesicle Production by Human Neutrophils"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Uncovering the Dynamics of Pulmonary Siglec-1+ Macrophages in Tuberculosis"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Mechanisms of Phagocytosis, Micropinocytosis and Cell Migration
9:00 am - 9:10 am
"Mechano-Redox Control of Mac-1 De-Adhesion from ICAM-1 by Protein Disulfide Isomerase Promotes Directional Movement of Neutrophils Under Flow"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Natural Antibodies as “Eat-Me” Signals for Phagocytosis of Necrotic Cell Debris at Sites of Tissue Injury"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Eosinophils and Neutrophils Exhibit Similar Chemotaxis Characteristics Despite a Clear Difference in Nuclear Morphology"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Examination of the Macrophage Responses to Reduced Efferocytosis: Does How You Eat Matter?"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Deciding What to Eat; When Neutrophils Have a Taster but not a Second Course"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Keratinocyte- and Keratin 17-Dependent Neutrophil Recruitment in Skin Inflammation"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Excess Plasma Membrane Mechanically Regulates Functional Decision-Making in Myeloid CellS"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Investigating Phagocytic Mechanosensing Using Engineered Hydrogel Particles"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentorship Panel: Toolkit for a Successful Career in Academia
1:30 pm - 2:10 pm
Panel Discussion
Toolkit for a Successful Career in Academia
2:10 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes