Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Methods and Models for Signaling in Phagocytes
3:45 pm - 3:55 pm
"Sterile Injury Micro-Physiological System for Demonstrating Neutrophil Reverse Migration via Macrophage Derived Extracellular Vesicles Interaction in vitro "
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Comparative Transcriptomic Profiling of Primary Hamster Macrophages Reveals Candidate Genes Driving Susceptibility to Leishmania Donovani Infection"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Fragmentation and Clearance of Apoptotic Cells is Dependent on Interactions Within the Tissue Environment"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Phagocytes Role in Inflammation and Disease
7:30 pm - 7:40 pm
"STAT-3-Dependent Suppression of Phagolysosomal Activity by IL-27 in Neonatal Macrophages Does Not Represent a Therapeutic Target for E.coli -Induced Neonatal Sepsis"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Antibiotic-Induced Disruption of the Gut Microbiota Impairs Phagocyte-Dependent Fungal Immunity"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Investigating Acute e-Cigarette Exposure Mediated Alterations in Neutropoiesis"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"SLAMF1 Promotes Protective Immunity Against M. tuberculosis Through Macrophage-T Cell Interaction"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"A Genome-Wide CRISPR Screen Identifies Cancer Cell Factors Affecting Trogocytosis Lethality"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"NLRP11 is Required for Canonical NLRP3 and Non-Canonical Inflammasome Activation During Human Macrophage Infection with Mycobacteria"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Phagocyte Dysfunction in Severe Aplastic Anemia is Alleviated by Resolvin E1"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"A Novel Bacterial Serine Protease Inhibitor (Serpin) Impairs Neutrophil Antimicrobial Activity"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Mechanistic Insights into Phagocyte Cell Function
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:15 am
"ACSS2-Driven Metabolic and Epigenetic Regulation of Macrophage Activation in Colitis"
9:15 am - 9:20 am
Discussion
9:20 am - 9:30 am
"Integrin aMß2 as a Key Regulator of the Anti-Inflammatory Cholinergic Response in Macrophages and Neutrophils"
9:30 am - 9:35 am
Discussion
9:35 am - 9:45 am
"Messy Eaters: Mechanisms of Trogocytic Membrane Exchange in Macrophages"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"The Legacy of Neutrophils-LANDVs (Large Aging Neutrophil Derived Vesicles)"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"The Lysosomal Solute Carrier SLC29A3 Modulates Phagosomal Dynamics and Promotes Autophagy in Murine Dendritic Cells"
10:15 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Interferons and Neutrophils: Unraveling Their Dialogue in Antifungal Immunity"
10:30 am - 10:35 am
Discussion
10:35 am - 10:45 am
"Receptor Activator of NF-?B Ligand Signaling Dampens Macrophage Innate Immune Responses"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Exploring Career Options in Immunology, Cell Biology, and Infectious Disease
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:20 pm
Panel Discussion
Exploring Career Options in Immunology, Cell Biology and Infectious Disease
2:20 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes