The Photonuclear GRC is a forum for presentation and discussion of the most recent results on frontier studies of the fundamental structure of matter, both visible and dark, using photon, electron and neutrino probes. The topics of the 2012 meeting will include recent advances in studies of the quark/gluon structure and excitation spectrum of nucleons, the spectroscopy of exotic hadrons, the structure of few-body and hyper nuclei, hadrons in the nuclear medium, nuclear structure at short distances and its quark-gluon dynamics, and astrophysical implications of photonuclear studies. Considerable time will be given for discussion of ideas, new trends and future opportunities of research in photonuclear reactions and related processes. Since 1959, the Photonuclear GRC has been an arena for new ideas and provided ample and unique opportunities for young scientists and leading researchers to interact in the most scientifically stimulating environment.